A função autor nos materias impressos do PEC - formação universitária e o desafio de escrever para professores

Pós-graduação em Educação - IBRC

PEC formação universitária: análise e discussão dos novos modelos formativos do Estado de São Paulo

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

O professor e sua formação: o impacto do PEC - formação universitária - ao professor da pessoa

Pós-graduação em Educação Escolar - FCLAR

A utilização de tecnologia na formação de professores: o programa de educação continuada PEC-Formação universitária do campus da Unesp em Marília/SP - um estudo de caso

Pós-graduação em Educação - FFC

O programa PEC - formação universitária e a formação de professores do ensino fundamental: uma avaliação

Pós-graduação em Educação - FFC

Ensino a distância: educação ou treinamento no PEC/FOR PROF?

Pós-graduação em Educação - FFC

O programa PEC/formação universitária: paradigma para qualificação docente na idade mídia

Pós-graduação em Educação - FFC

3,5-Dimethyl-1-thiocarbamoylpyrazole and its Pd(II) complexes: Synthesis, spectral studies and antitumor activity

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Detection of turkey astrovirus in young poults affected with poult enteritis complex in Brazil

Reverse transcription polymerase chain reaction (RT-PCR) of turkey astrovirus (TAstV) capsid and polymerase genes was applied to the bursa of Fabricius (BF), thymus (TH), spleen (SP) and cloacal swabs (CS) of young poults with "Poult enteritis complex" (PEC). The histological lesions included atrophy, lymphoid depletion, cellular infiltration and necrosis of the BF, TH and SP, respectively. The RT-PCR reactions were positive for the polymerase gene of TAstV-2 in all 100 CSs, 7 out of 10 of BFs and 10 out of 20 THs and SPs, respectively. Five out of 10 THs and SPs samples, considered to be negative by RT-PCR, were positive when specific primers designed for the TAstV-2 capsid gene were applied. This is the first description of turkey astrovirus infection presenting PEC in Latin America.

Upregulation of muscarinic receptors by long-term nitric oxide inhibition in the rat ileum

1. The aim of the present study was to examine the effects of long-term nitric oxide (NO) blockade on contractions of the rat ileum induced by muscarinic agonists.2. Male Wistar rats received the NO synthesis inhibitor N (G) -nitro-l-arginine methyl ester (l-NAME; 20 mg/rat per day) in drinking water for 7, 15, 30 and 60 days. Concentration-responses curves to methacholine and carbachol were obtained and pEC(50) values were calculated. Saturation binding assays were performed in membranes prepared from rat ileum after 60 days of l-NAME treatment and the dissociation constant (K-D ) and maximal number of binding sites (B-max ) were determined by Scatchard analysis.3. The NO synthase activity of the ileum was markedly reduced in all l-NAME-treated groups. At 60 days after l-NAME treatment, a significant increase in the potency of methacholine (fourfold) and carbachol (threefold) was observed. In binding studies, we found a significant increase in B-max for [(3) H]-quinuclidinyl benzilate of approximately 57% in the l-NAME treated group without any significant change in K-D values. The contractile response to methacholine was not modified by the soluble guanylate cyclase inhibitor 1H-[1,2,4]oxadiazolo-[4,3-a]quinoxalin-1-one (3 mumol/L). No morphological alterations in the rat ileum were observed in l-NAME-treated rats.4. Our findings suggest that treatment with l-NAME for 60 days induces a marked increase in the potency of methacholine and carbachol, as well as an increase in receptor number in the rat ileum.

High-fat diet associated with obesity induces impairment of mouse corpus cavernosum responses

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Influence of acute pancreatitis on the in vitro responsiveness of rat mesenteric and pulmonary arteries

Background: Acute pancreatitis is an inflammatory disease characterized by local tissue injury and systemic inflammatory response leading to massive nitric oxide (NO) production and haemodynamic disturbances. Therefore, the aim of this work was to evaluate the vascular reactivity of pulmonary and mesenteric artery rings from rats submitted to experimental pancreatitis.Male Wistar rats were divided into three groups: saline (SAL); tauracholate (TAU) and phospholipase A(2) (PLA(2)). Pancreatitis was induced by administration of TAU or PLA(2) from Naja mocambique mocambique into the common bile duct of rats, and after 4 h of duct injection the animals were sacrificed. Concentration-response curves to acetylcholine (ACh), sodium nitroprusside (SNP) and phenylephrine (PHE) in isolated mesenteric and pulmonary arteries were obtained. Potency (pEC(50)) and maximal responses (E(MAX)) were determined. Blood samples were collected for biochemical analysis.Results: In mesenteric rings, the potency for ACh was significantly decreased from animals treated with TAU (about 4.2-fold) or PLA(2) (about 6.9-fold) compared to saline group without changes in the maximal responses. Neither pEC(50) nor E(MAX) values for Ach were altered in pulmonary rings in any group. Similarly, the pEC(50) and the E(MAX) values for SNP were not changed in both preparations in any group. The potency for PHE was significantly decreased in rat mesenteric and pulmonary rings from TAU group compared to SAL group (about 2.2- and 2.69-fold, for mesenteric and pulmonary rings, respectively). No changes were seen in the E(MAX) for PHE. The nitrite/nitrate (NO(x)(-)) levels were markedly increased in animals submitted to acute pancreatitis as compared to SAL group, approximately 76 and 68% in TAU and PLA(2) protocol, respectively.Conclusion: Acute pancreatitis provoked deleterious effects in endothelium-dependent relaxing response for ACh in mesenteric rings that were strongly associated with high plasma NO(x)(-) levels as consequence of intense inflammatory responses. Furthermore, the subsensitivity of contractile response to PHE in both mesenteric and pulmonary rings might be due to the complications of this pathological condition in the early stage of pancreatitis.

Feeding associations between Guiana dolphins, Sotalia guianensis (Van Bénèden, 1864) and seabirds in the Lagamar estuary, Brazil

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Guiana dolphins, Sotalia guianensis (Cetacea: Delphinidae), in the Paranaguá Estuarine Complex: insights on the use of area based on the photo-identification technique

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Leituras profissionais docentes e apropriação de saberes acadêmico-educacionais

O artigo focaliza processos relacionados ao movimento atual de universitarizaçãoda docência, procurando caracterizar modos pelos quais professoras das quatro primeiras séries do ensino fundamental leram e se apropriaram de textos acadêmico-educacionais em um contexto de educação continuada. As análises apresentadas foram elaboradas no âmbito de uma investigação etnográfica, realizada em dois pólos do Programa de Educação Continuada - PEC - Formação Universitária (São Paulo). Observou-se que a atuação de diversos dispositivos em tais contextos, assim como nos textos lidos, favoreceu a instauração de um novo padrão de leituraentre as professoras. As posturas e os procedimentos por elas assumidos, por sua vez, sugeriram a existência de uma leitura profissional propriamente docente, caracterizada entre outros aspectos por uma racionalidade prática que possibilitava às professoras subvertera ordem dos discursos presente nos textos. A centralidade dossaberes e interesses práticos das docentes para a configuração de suas leituras de caráter profissional reafirma a importância da cultura pedagógica compartilhada no magistério como fonte de conhecimentos mais pertinentes para o ensino e como eixo da formação docente.