Clinical evaluation of enalapril maleate and furosemide usage in dogs with degenerative myxomatous mitral valve, CHF functional class Ib

A doença degenerativa mixomatosa da válvula mitral (DDMVM) é uma cardiopatia de alta incidência na clínica médica de pequenos animais, acometendo mormente cães idosos e raças de pequeno porte. Desta forma, foi realizada uma investigação científica objetivando avaliar clinicamente a utilização dos fármacos maleato de enalapril e furosemida em cães com a referida enfermidade na classe funcional Ib da ICC, antes e após a terapêutica implantada. Para isso, utilizaram-se 16 cães portadores da valvulopatia supracitada, distribuídos em dois grupos; com o primeiro recebendo furosemida (n=8) e o segundo maleato de enalapril (n=8), durante 56 dias. Os cães foram avaliados em quatro momentos (T0, T14, T28 e T56 dias) quanto aos sinais clínicos e parâmetros hematológicos e bioquímico-séricos, que incluíram concentrações séricas da enzima conversora da angiotensina (ECA) e aldosterona, como também avaliações radiográficas, eletrocardiográficas, ecodopplercardiográficas e da pressão arterial. Os resultados quanto aos parâmetros clínicos, avaliações hematológicas e bioquímicas séricas não revelaram alterações significativas em ambos os grupos, mas reduções significativas nos valores de ECA e aldosterona no grupo que recebeu o maleato de enalapril foram identificadas. Ao exame radiográfico observou-se reduções nos valores de VHS e na variável onda Pms do eletrocardiograma em ambos os grupos, mas sem alterações nos valores da pressão arterial. Por sua vez, o ecodopplercardiograma evidenciou diminuição significativa das variáveis DIVEd/s nos grupos estudados e na FEC% nos cães que receberam somente enalapril. Portanto, a análise dos resultados encontrados indicou que a monoterapia fundamentada no maleato de enalapril apresentou melhor eficiência no controle do quadro clínico em pacientes da classe funcional Ib da ICC.

Physical attributes of kaolinitic and oxidic oxisols resulting from different usage systems

A mineralogia da fração argila e os sistemas de uso exercem fundamental importância na estrutura do solo. Assim, objetivou-se avaliar atributos físicos de um Latossolo Vermelho Distrófico, caulinítico (LVd), e, de um Latossolo Vermelho Eutroférrico, oxídico (LVef), sob diferentes sistemas de uso, localizados no município de Jaboticabal (SP), Brasil. Os sistemas de uso foram: cana-de-açúcar; algodão e mata. Foram avaliadas a densidade do solo, porosidade total, macro e microporosidade, nas profundidades de 0,0-0,1, 0,1-0,2, 0,2-0,3, 0,3-0,4 m. O Latossolo caulinítico (LVd) apresentou maior densidade do solo e menor porosidade total, macro e microporosidade. O uso aumentou a densidade do solo na profundidade de 0,0-0,3 m, com efeitos maiores no Latossolo caulinítico, principalmente na profundidade de 0,1-0,2 m na área cultivada com cana-de-açúcar.

Comparison between intermittent mandatory ventilation and synchronized intermittent mandatory ventilation with pressure support in children

Objective: To compare intermittent mandatory ventilation (IMV) with synchronized intermittent mandatory ventilation plus pressure support (SIMV+PS) in terms of time on mechanical ventilation, duration of weaning and length of stay in a pediatric intensive care unit (PICU).Methods: This was a randomized clinical trial that enrolled children aged 28 days to 4 years who were admitted to a PICU between October of 2005 and June of 2007 and put on mechanical ventilation (MV) for more than 48 hours. These patients were allocated to one of two groups by drawing lots: IMV group (IMVG; n = 35) and SIMV+PS group (SIMVG; n = 35). Children were excluded if they had undergone tracheotomy or had chronic respiratory diseases. Data on oxygenation and ventilation were recorded at admission and at the start of weaning.Results: There were no statistical differences between the groups in terms of age, sex, indication for MV, PRISM score, Comfort scale, use of sedatives or ventilation and oxygenation parameters. The median time on MV was 5 days for both groups (p = 0.120). There were also no statistical differences between the two groups for duration of weaning [IMVG: 1 day (1-6) vs. SIMVG: 1 day (1-6); p = 0.262] or length of hospital stay [IMVG: 8 days (2-22) vs. SIMVG: 6 days (3-20); p = 0.113].Conclusion: Among the children studied here, there was no statistically significant difference between IMV and SIMV+ PS in terms of time on MV, duration of weaning or time spent in the PICU.ClinicalTrials.govID: NCT00549809.

The Fulling-Davies-Unruh effect is mandatory: the proton's testimony

We discuss the decay of accelerated protons and illustrate how the Fulling-Davies-Unruh effect is indeed mandatory to maintain the consistency of standard Quantum Field Theory. The confidence level of the Fulling-Davies-Unruh effect must be the same as that of Quantum Field Theory itself.

SEASONAL SPACE USAGE BY THE INTRODUCED PHARAOHS ANT, MONOMORIUM-PHARAONIS (L) (HYM, FORMICIDAE), IN INSTITUTIONAL SETTINGS IN BRAZIL AND ITS RELATION TO OTHER STRUCTURAL ANT SPECIES

In an institutional setting in Brazil, the pharaoh's ant, Monomorium pharaonis was found to be the dominant and most abundant ant present throughout the year. The only other regularly collected ant was the exotic Tapinoma melanocephalum. However, M. pharaonis dominated bait station visitations, although locally concentrated, with other species restricted to regions in which M. pharaonis was not found.

Usage of enterprise modeling processes and information systems design to forecast demand

Managing the great complexity of enterprise system, due to entities numbers, decision and process varieties involved to be controlled results in a very hard task because deals with the integration of its operations and its information systems. Moreover, the enterprises find themselves in a constant changing process, reacting in a dynamic and competitive environment where their business processes are constantly altered. The transformation of business processes into models allows to analyze and redefine them. Through computing tools usage it is possible to minimize the cost and risks of an enterprise integration design. This article claims for the necessity of modeling the processes in order to define more precisely the enterprise business requirements and the adequate usage of the modeling methodologies. Following these patterns, the paper concerns the process modeling relative to the domain of demand forecasting as a practical example. The domain of demand forecasting was built based on a theoretical review. The resulting models considered as reference model are transformed into information systems and have the aim to introduce a generic solution and be start point of better practical forecasting. The proposal is to promote the adequacy of the information system to the real needs of an enterprise in order to enable it to obtain and accompany better results, minimizing design errors, time, money and effort. The enterprise processes modeling are obtained with the usage of CIMOSA language and to the support information system it was used the UML language.

Monitoring of hydrogen sulfide via substrate-integrated hollow waveguide mid-infrared sensors in real-time

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Subjective assessment of adhesives usage by complete denture wearers in a brazilian population

The information about the knowledge and usage of denture adhesives is still limited, particularly in Brazilian populations. Objective: The purpose of this study was to investigate the aspects related to the use or nonuse of denture adhesives by complete denture wearers. Material and method: Questionnaires were applied to 100 bimaxillary complete denture wearers concerning their usage of denture adhesives. The survey was carried out according to three categories: those who had never tried adhesive, those who had tried adhesive at least once but no longer used it, and those who currently used it. Result: Of the 100 participants, 80% had never tried adhesives, 16% had tried at least once but no longer used it and 4% had used on a regular basis. Conclusion: Within the limitations of this study, the results of this subjective assessment suggest that within the participants that had never tried adhesives, 77.5% inform that the adhesive is not needed, and all participants who regularly use it inform its efficiency.