Role of protease-activated receptor-2 in inflammation, and its possible implications as a putative mediator of periodontitis

Proteinase-activated receptor-2 (PAR2) belongs to a novel subfamily of G-protein-coupled receptors with seven-transmembrane domains. This receptor is widely distributed throughout the body and seems to be importantly involved in inflammatory processes. PAR2 can be activated by serine proteases such as trypsin, mast cell tryptase, and bacterial proteases, such as gingipain produced by Porphyromonas gingivalis. This review describes the current stage of knowledge of the possible mechanisms that link PAR2 activation with periodontal disease, and proposes future therapeutic strategies to modulate the host response in the treatment of periodontitis.

Apoptosis as a mediator of hyperplastic recovery in human prostate lesions: cytochemical and immunocytochemical evaluation

The present study was carried out to investigate the occurrence of apoptosis in human prostatic lesions with emphasis on nodular hyperplasia and adenocarcinomas, using cytochemistry and immunocytochemistry. The results showed that apoptosis is a common event on nodular hyperplasia but not in adenocarcinomas. This led to the hypothesis that apoptosis may represent an important factor on the localized recovery response of the hyperplastic acini.

Vizinhança global ou proximidade imposta? Impactos da comunicação intercultural mediada por computador sobre o papel da cultura no ensino de língua inglesa

Muitas práticas educacionais no ensino e aprendizagem de línguas parecem ainda dominadas por uma visão de cultura essencialista, na qual os alunos, suas habilidades e atitudes de aprendizagem são caracterizadas por estereótipos problemáticos e/ou imaginários de suas culturas religiosas, étnicas e nacionais. As novas ferramentas e aplicativos para comunicação trazidos pela internet têm contribuído para o aumento de práticas comunicativas entre indivíduos de diferentes culturas e o uso da língua inglesa entre falantes não nativos, o que também tende a trazer impactos sobre a maneira como entendemos e ensinamos cultura na aprendizagem de tal língua. Este artigo pretende explicitar a visão de cultura presente nos conceitos de competência comunicativa e competência intercultural, e discutir a necessidade de reformulação do componente cultural no ensino e aprendizagem de línguas, para que ele objetive a exploração da complexidade advinda do pragmatismo dos encontros interculturais na contemporaneidade.

A articulação língua-cultura na coconstrução da competência intercultural em uma parceria de Teletandem (Português/Espanhol)

Pós-graduação em Estudos Linguísticos - IBILCE

Recombinant disintegrin targets alpha(v) beta(3) integrin and leads to mediator production

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Citral and eugenol modulate DNA damage and pro-inflammatory mediator genes in murine peritoneal macrophages

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Relações públicas e a mediação do diálogo intercultural na comunicação organizacional

The large flow of businesses going abroad generates an ever more diverse internal multicultural organizational scenario. Different national cultures inside an organization can directly influence the management of people. Human values, languages, customs, work modes/routines and different habits can create conflicts among parties. This study deals with the role of Public Relations as a tool/strategy to deal with conflicting intercultural communication inside business organizations. The analysis is grounded on theoretical principles concerning the roles of communication professionals as the individuals responsible for the relationship between an institution and the internal public. The study introduces intercultural communication as a growing area to be explored by the Public Relations professional and highlights the possibility of emerging innovative solutions for organizational problems. It also brings reports by professionals that have intercultural experience concerning Brazil and Germany in an attempt to illustrate conflicts that might have been prevented by actions taken by a specialist in Communication in order to promote mutual understanding

O professor e a prática telecolaborativa no teletandem

The new technologies have increasingly provided access to foreign languages and cultures and also to authentic communication. If we consider that the foreign languages teaching/learning process and teachers’ education can be enriched by telecollaboration, I believe it is necessary to observe the roles played by language teachers. Based on an ethnographic qualitative study carried out with Brazilian and foreign university students, this paper focuses on teletandem practice, a distance tandem modality carried out by audio and video conferences with resources such as Windows Live Messenger, Skype or ooVoo, to investigate roles played by language teachers in telecollaborative practice. The data were collected from (a) e-mails exchanged between the partners and between partners and the mediator-teacher; (b) DVDs of interaction sessions recordings; (c) written teletandem sessions recordings; (d) recordings of interviews between the partners and the researcher at ooVoo; (e) fi eld notes taken at Teletandem Laboratory at UNESP- Assis; and (f) participants’ written reports. The data analysis, from the hermeneutic interpretative perspective, revealed that the teacher is not ignored but is given new roles to maximize the process towards meaningful and intercultural learning.

O desestranhamento em relação ao alemão na aprendizagem do idioma: um processo de aproximação ao outro sob a perspectiva da competência intercultural

This article aims to approach, under a critical perspective, images about German language and their speakers, presented by Brazilian university students interested in or engaged in learning this language in the first stage of studies. The purpose is to deal with evidences of the occurrence of stereotypical images and to discuss their implications in/for the teaching-learning process, aiming with this study to show the importance of considering and establishing as a relevant goal in the teaching of German, the necessity of a destrangement route or period, through a methodological approach aimed at helping the students in the process of developing intercultural competence. Such discussions are founded in theoretical conceptions related to the notions of other and self, intercultural competence, intercultural approach, as well as in results obtained through an investigation conducted within the field of foreign language (German) learning.

A universidade no contexto internacional: o relações públicas como mediador intercultural no projeto Brasil de Todo Mundo

The following dissertation aims to propose an institutional and intercultural projecy of reception and integration of foreign students from academic mobility programs for the campus unit of Bauru. Such action is necessary because of the absence of a reception program of these students, the reception and integration into the social and cultural reality of the place in which they live is a fundamental part of international experience. As an example for this institutional proposal, we discuss the extension of project experience Brasil de Todo Mundo, which aims to deepen the reflections on the Brazilian cultural universe for foreign students who are in Brazil over a period, while taking academic mobility in the Universidade Estadual Paulista, Bauru campus. Student leadership project, Brasil de Todo Mundo emerged from the international experience in mobility programs offered by UNESP, from students of campus Bauru, when in the back of their experiences, they realized that they could continue being tourists your own country with the reception of foreign students. In addition, the identification of expectations in social and intercultural skills, in addition to reasons connected with the increase academic and language skills are a form of very strong approach, which helps in creating intercultural dialogue spaces between the students, the main objective of the project

Grafismos no projeto Botuáfrica: um diálogo intercultural

This article aims to present the Botuafrica Project and graphism generated by the stencil printing process. We will address the issue of valuing African-Brazilian aesthetics by producing symbols created by the participants of the project and fashion as a vehicle for social inclusion in the context of Botucatu Municipality of state of São Paulo. The study proposes a reflection on the work of professionals that contributed on practices of technical and concept development in order to promote the creation of local fashion and production. This research will verify the implications of act of drawing, printing and wearing the textiles designed by the participants of the project. Botucatu Institute collected and archived photos and drawings during the project between years 2010 and 2012 and provided this material for this research.

Pollination of Anemopaegma album (Bignoniaceae) with focus on floral nectar as the mediator of interactions with mutualistic and antagonistic bees

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)