Generalized linear mixed models for the genetic evaluation of binary reproductive traits: a simulation study

The objective of this study was to evaluate the use of probit and logit link functions for the genetic evaluation of early pregnancy using simulated data. The following simulation/analysis structures were constructed: logit/logit, logit/probit, probit/logit, and probit/probit. The percentages of precocious females were 5, 10, 15, 20, 25 and 30% and were adjusted based on a change in the mean of the latent variable. The parametric heritability (h²) was 0.40. Simulation and genetic evaluation were implemented in the R software. Heritability estimates (ĥ²) were compared with h² using the mean squared error. Pearson correlations between predicted and true breeding values and the percentage of coincidence between true and predicted ranking, considering the 10% of bulls with the highest breeding values (TOP10) were calculated. The mean ĥ² values were under- and overestimated for all percentages of precocious females when logit/probit and probit/logit models used. In addition, the mean squared errors of these models were high when compared with those obtained with the probit/probit and logit/logit models. Considering ĥ², probit/probit and logit/logit were also superior to logit/probit and probit/logit, providing values close to the parametric heritability. Logit/probit and probit/logit presented low Pearson correlations, whereas the correlations obtained with probit/probit and logit/logit ranged from moderate to high. With respect to the TOP10 bulls, logit/probit and probit/logit presented much lower percentages than probit/probit and logit/logit. The genetic parameter estimates and predictions of breeding values of the animals obtained with the logit/logit and probit/probit models were similar. In contrast, the results obtained with probit/logit and logit/probit were not satisfactory. There is need to compare the estimation and prediction ability of logit and probit link functions.

Multiobjective linear model for pre-feasibility design of cogeneration systems

This article deals with some methodologies for economic and technical evaluations of cogeneration projects proposed by several authors. A discussion on design philosophy applied to thermal power plants leads to the decision problem of a conflicting, multiobjective formulation that includes the most important parameters. This model is formulated to help decision makers and designers in choosing compromise values for included parameters. (C) 1997 Elsevier B.V. Ltd.

BRST-BFV formalism for the generalized Schwinger model

We derive the Wess-Zumino scalar term of the generalized Schwinger model both in the singular and nonsingular cases by using BRST-BFV framework. The photon propagators are also computed in the extended Lorentz gauge.

Hamiltonian quantization of the non-anomalous generalized Schwinger model

We quantize a generalized version of the Schwinger model, where the two chiral sectors couples with different strengths to the U(1) gauge field. Starting from a theory which includes a generalized Wess-Zumino term, we obtain the equal time commutation relation for physical fields, both the singular and non-singular cases are considered. The photon propagators are also computed in their gauge dependent and invariant versions. © 1995 Springer-Verlag.

Linear and Poisson models for genetic evaluation of tick resistance in cross-bred Hereford x Nellore cattle

Cattle resistance to ticks is measured by the number of ticks infesting the animal. The model used for the genetic analysis of cattle resistance to ticks frequently requires logarithmic transformation of the observations. The objective of this study was to evaluate the predictive ability and goodness of fit of different models for the analysis of this trait in cross-bred Hereford x Nellore cattle. Three models were tested: a linear model using logarithmic transformation of the observations (MLOG); a linear model without transformation of the observations (MLIN); and a generalized linear Poisson model with residual term (MPOI). All models included the classificatory effects of contemporary group and genetic group and the covariates age of animal at the time of recording and individual heterozygosis, as well as additive genetic effects as random effects. Heritability estimates were 0.08 ± 0.02, 0.10 ± 0.02 and 0.14 ± 0.04 for MLIN, MLOG and MPOI models, respectively. The model fit quality, verified by deviance information criterion (DIC) and residual mean square, indicated fit superiority of MPOI model. The predictive ability of the models was compared by validation test in independent sample. The MPOI model was slightly superior in terms of goodness of fit and predictive ability, whereas the correlations between observed and predicted tick counts were practically the same for all models. A higher rank correlation between breeding values was observed between models MLOG and MPOI. Poisson model can be used for the selection of tick-resistant animals. © 2013 Blackwell Verlag GmbH.

A Multi-Stage Stochastic Non-Linear Model for Reactive Power Planning Under Contingencies

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Non-destructive linear model for leaf area estimation in Vernonia ferruginea Less

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Análise das relações da curva de crescimento e eficiência produtiva de vacas da raça Holandesa

O objetivo neste trabalho foi analisar as relações entre parâmetros da curva de crescimento (peso à maturidade e taxa de maturação) e medidas da eficiência produtiva de 333 vacas da raça Holandesa nascidas de 1992 a 2002. Dados de idade ao primeiro parto, produção de leite e duração da primeira lactação, primeiro intervalo de partos e produção de leite por dia de intervalo de partos foram analisados por meio de um modelo linear generalizado com o efeito fixo de grupo contemporâneo (ano-estação de nascimento), os efeitos aleatórios de pai da vaca e erro e os efeitos lineares e quadráticos do peso à maturidade e da taxa de maturação. Nas análises de longevidade e de duração da vida útil, incluiu-se o efeito fixo de motivo de descarte da vaca. Houve efeitos linear e quadrático da taxa de maturação sobre a maioria das características, exceto o primeiro intervalo de partos e a produção de leite por dia de intervalo de partos. As estimativas das taxas de maturação ótimas variaram de 0,0896 a 0,1187 kg/kg de peso vivo/mês. O peso à maturidade influenciou a longevidade de forma linear e quadrática. A combinação ótima foi de 701 kg de peso à maturidade e 0,0934 kg/kg de peso vivo/mês de taxa de maturação. O peso à maturidade correlacionou-se de forma desfavorável com a duração da primeira lactação (-0,11). Coeficientes de correlação significativos foram obtidos entre taxa de maturação e idade ao primeiro parto (-0,22), produção de leite na primeira lactação (0,18), duração da primeira lactação (0,18) e longevidade (0,14), o que confirma a hipótese de que vacas com taxas de maturação mais rápidas apresentam maior eficiência produtiva.

Late administration of a specific COX-2 inhibitor does not treat and/or prevent progression of gastric tumors in rats submitted to duodenogastric reflux procedure

PURPOSE:To assess whether late introduction of a specific COX-2 inhibitor (Meloxicam) can treat and/or prevent the progression of tumors in the stomach of rats submitted to duodenogastric reflux. METHODS: Seventy five male Wistar rats, weighing 150 grams, were submitted to the induction of duodenogastric reflux through the pylorus. At 36 weeks of follow-up were established three experimental groups: DGR36 sacrificed immediately, DGR54 and DGR54MLX both sacrificed at 54th week of follow-up . The animals of the latter group were fed with a rat chow premixed with Meloxicam (2.0 mg/ kg feed; 0.3 mg / kg bw / day) and the other two with standard rat chow. The lesions found in the pyloric mucosa and gastrojejunal anastomosis were analyzed macroscopically and histologically. For statistical analysis was adjusted a generalized linear model assuming a binomial distribution with LOGIT link function. RESULTS: No significant differences were found when comparing the incidences of benign tumor lesions (Adenomatous Hyperplasia), p=0.4915, or malignant (Mucinous Adenocarcinoma), p=0.2731, among groups. CONCLUSION: Late introduction of specific COX-2 inhibitor (Meloxicam) did not treat and was not able to prevent the progression of tumoral lesions induced by duodenogastric reflux in the rat stomachs.

Effects of sex and locality on the abundance of lice on the wild rodent Oligoryzomys nigripes

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Interação entre grau de perda auditiva e o incômodo com zumbidos em trabalhadores com história de exposição ao ruído

Hearing loss and tinnitus impact the lives of workers in every instance of their lives. Aim: this paper aims to investigate the existence of a dose-response relationship between hearing loss and tinnitus by determining whether higher levels of hearing loss can be associated with increased tinnitus-related discomfort. Materials and method: this cross-sectional case study assessed 284 workers exposed to occupational noise through pure tone audiometry. Test results were categorized as defined by Merluzzi. Individuals complaining of tinnitus answered the adapted and validated Brazilian Portuguese version of the Tinnitus Handicap Inventory. A generalized linear model was adjusted for binomial data to test the interaction between these factors. Results: over 60% of the ears analyzed had hearing loss, while more than 46% of them had tinnitus. Tinnitus prevalence and risk rates increased as pure tone audiometry results got worse. The association between both, considering all hearing loss degrees, was statistically significant. Conclusion: the results point to a statistical association between hearing loss and tinnitus; the greater the hearing loss, the greater the discomfort introduced by tinnitus. 2009 © Revista Brasileira de Otorrinolaringologia.

Detection of cavitated approximal surfaces using cone beam CT and intraoral receptors

Objectives: The aim of this study was to compare cone beam CT (CBCT) in a small field of view (FOV) with a solid-state sensor and a photostimulable phosphor plate system for detection of cavitated approximal surfaces. Methods: 257 non-filled approximal surfaces from human permanent premolars and molars were recorded by two intraoral digital receptors, a storage phosphor plate (Digora Optime, Soredex) and a solid-state CMOS sensor (Digora Toto, Soredex), and scanned in a cone beam CT unit (3D Accuitomo FPD80, Morita) with a FOV of 4 cm and a voxel size of 0.08 mm. Image sections were carried out in the axial and mesiodistal tooth planes. Six observers recorded surface cavitation in all images. Validation of the true absence or presence of surface cavitation was performed by inspecting the surfaces under strong light with the naked eye. Differences in sensitivity, specificity and agreement were estimated by analysing the binary data in a generalized linear model using an identity link function. Results: A significantly higher sensitivity was obtained by all observers with CBCT (p,0.001), which was not compromised by a lower specificity. Therefore, a significantly higher overall agreement was obtained with CBCT (p,0.001). There were no significant differences between the Digora Optime phosphor plate system and the Digora Toto CMOS sensor for any parameter. Conclusions: CBCT was much more accurate in the detection of surface cavitation in approximal surfaces than intraoral receptors. The differences are interpreted as clinically significant. A CBCT examination performed for other reasons should also be assessed for approximal surface cavities in teeth without restorations. © 2013 The British Institute of Radiology.

Dinâmica populacional, anautogenia e dependência da ansiedade em moscas-varejeiras: experimentação e teoria populacional

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Modelagem estatística do frete da madeira no Uruguai

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Efeito da participação e do desligamento de programa de mudança no estilo de vida sobre o nível de atividade e aptidão física, percepção de saúde e presença de síndrome metabólica em adultos da comunidade de Botucatu - SP

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)