Zombando se dizem as verdades: uma análise da comicidade na narrativa anônima Obras do diabinh

Pós-graduação em Estudos Literários - FCLAR

O amor cortês e os Lais de Maria de França: um olhar historiográfico

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

O professor e o lúdico na educação infantil: um estudo das concepções sobre o brincar em histórias de vida

Pós-graduação em Psicologia - FCLAS

Homo Risibilis: ensaio sobre o processo de construção do humor nas obras infantis de Monteiro Lobato

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Ivabradine: Just another New Pharmacological Option for Heart Rate Control?

Ivabradine (IVB) is a heart rate lowering agent that acts via selective inhibition of the pacemaker funny current in sinoatrial nodal P cells, thus, reducing heart rate at rest and during exercise with minimal effect on myocardial contractility, blood pressure, and intracardiac conduction. IVB exerts no effect on external respiratory function parameters and it may also play a role in patients with concurrent chronic obstructive pulmonary disease. This property constitutes an important advantage over β-blockers. IVB acts by reducing the heart rate in a mechanism different from β-blockers, calcium channel blockers or late sodium channel blockers, three commonly prescribed antianginal drugs. As clinical trials have shown, it is remarkably well-tolerated and offers an alternative for patients who cannot take β-blockers. The combination of IVB and atenolol at commonly used doses in patients with chronic stable angina produced additional efficacy with no untoward effect on safety or tolerability. Additionally, side effects are rare and largely limited to a luminous phenomenon or phosphenes. This sensation is thought to be due to a block of Ih in the retina, a current very similar to cardiac If channels. IVB is contraindicated in patients with sick sinus syndrome or sinus node dysfunction and in patients taking hepatic inhibitors of Cytochrome P450 family 3, subfamily A, polypeptide 4 (abbreviated CYP3A4), with exception of omeprazole or lansoprazole. This review briefly summarizes the main studies regarding this drug.

Arremessadas da turma de caminhão: literatura e experiência traumática entre as trabalhadoras boias-frias na obra de Murilo Carvalho

This article investigates the universe of women seasonal farm workers, more precisely those women laborers who take the so-called truck, in the newspaper chronicle “Th e Seasonal Farm Workers’ Express” (1976) and the short story “Th e funny face of fear”(1978), both by the journalist and creative writer Murilo Carvalho. Th e hypothesis is that these two narratives, in which the theme is the truck accident, can be classifi ed as testimonial literature.