979 resultados para ExLibris
em Repositório Institucional UNESP - Universidade Estadual Paulista "Julio de Mesquita Filho"
Resumo:
Together with the increase of environmental degradation in the past few decades, the environmental education (EE) has emerged and grown all around the world. It is worrying the frequent assigning of stereotypes to the animals and the cases of disrespect to them. For these matters it was studied the presence and importance attributed to animals in the annals of six editions of an event of great significance in the field of Environmental Education, the meetings Pesquisa em Educação Ambiental (EPEAs). The animals were chosen for deserving more attention in the preservationist context, besides allowing the use of a great extent of activities in EE, regarding scholar and non-scholar organizations. The articles that presented descriptors related to animals in the title, keywords or abstract were analyzed in depth and characteristics such as segmentation of the studied population, locations where jobs tend to be performed, prevailing aspects and didactic material production, among others, were investigated and compared. It was also verified which current trends on Environmental Education currents are more frequently presented in the EPEAs articles, in order to map the Environmental Education in Brazil in the past few years, using as a basis an important theoretical framework in the area. Through the use of descriptors it was possible to define the articles that would be analyzed in depth, which is less than 6% of the total work published and represents that, until the sixth edition, the EPEAs have a minor amount of works concerning animal matters. In many of these articles animals were superficially worked, which demonstrates the necessity of approaches not only involving more the animals, but also addressing the complex environmental matter. Several trends were identified in various EE currents, coexisting and also conflicting in the field of Brazilian Environmental Education. It was observed, in several cases, two or more trend currents in the ...
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O presente trabalho visa analisar os reais impactos políticos, econômicos e sociais ocorridos na África do Sul decorrentes do fato de ter sediado a Copa do Mundo FIFA de 2010 além de procurar analisar os eventuais impactos que o Brasil eventualmente sofrerá como sede da Copa do Mundo FIFA de 2014. Por meio da leitura de artigos, trabalhos científicos, livros e websites procurei demonstrar as conseqüências para a África do Sul bem como as expectativas para o Brasil em relação ao evento. Além da análise dos resultados socioeconômicos obtidos na África do Sul em 2010 e procurar mensurar os impactos que o Brasil há de sofrer em 2014 por sediar a Copa, esta monografia ainda apresenta a característica que este megaevento esportivo tem de alterar a economia dos países-sede e movimentar quantias consideráveis de dinheiro. Como resultado da pesquisa, podemos dizer que a primeira Copa sediada no continente africano foi bem sucedida em termos político-sociais, pois, apesar das dificuldades, conseguiram passar uma boa imagem do país para o mundo mostrando ser um povo hospitaleiro, alegre e simpático. Para o caso do Brasil, sabe-se que incentivará o problema da corrupção, da violência urbana e da diferencia entre as classes sociais, porém é uma grande oportunidade para o desenvolvimento econômico do país e de conquistar lugares no cenário político mundial jamais antes conseguidos
Resumo:
This study aims to conduct a comparative analysis of the cover stories of magazines Atrevida, published by Escala, Capricho, published by Abril, and Todateen, published by AltoAstral, published between 2008 and 2012, which give prominence to the phenomena with more recurring presence on the covers. The objective of the research is to analyze the criteria for newsworthiness adopted by publications targeting a teenage audience, relating them to cover highlights involving idols of that audience. As object, we study the press coverage given to four magazines phenomena of cultural industry: the actors in the Twilight saga, the actors of the Disney Channel series, singer Justin Bieber and actors of Brazilian soap opera Rebelde. The work begins with a history of magazine journalism, from its origin to the journalism geared toward teenage readers, through the history of women's magazines and variety. Then, we present the theoretical concepts from the Theory News (Traquina) in confrontation with the notions of consumption (Canclini) and behavior (Featherstone). Finally, analysis of the corpus, which was defined by a cutout thematic within this period, divided into two major groups of news reports: those in which the idol is the news, and those in which he serves as a guide for the reader
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Aortic regurgitation (AR) is still common in developing countries as secondary of rheumatic fever, and its incidence have increased in senile degenerative form. The AR develops severe myocardial hypertrophy. A common comorbidity associated with cardiovascular disease is depression. Among the most prescribed antidepressants in the world are the serotonin selective reuptake inhibitors (SSRIs). Central serotonergic pathways are involved with the inhibition of sodium intake and can be modify the excretion of this íon. Therefore, we investigated whether treatment with an antidepressants SSRI, the paroxetine, for four weeks can modfy the behavior of water and NaCl 0,3M intake, excretion of sodium and morphofunctional parameters of rats with AR induce. Wistar rats (280 - 300g) underwent surgery for AR (n=15) or control surgery (n=14). The AR was induced by retrograde puncture of valve leaflets. The animals were divided into 4 groups: AR + paroxetine (n=8), AR + control (n=7), control + paroxetine (n=7), control + control (n=7). From the 4th to the 8th week after inductuin of AR was administered paroxetine (10mg/kg pc) daily and subcutaneously. In the 4th and 8th week after induction of AR echocardiograms were performed to collect data morphofunctional. During the 4 weeks of treatment were analyzed intake of water and saline daily and once a week urine samples were collected for analysis by flame photometer of excretion of sodium and potassium. In the 10th week the animals were submitted to a challenge protocol hidromineral by combining furosemide (10 mg / kg bw) associated with the low dose of Captopril (5 mg / kg bw). During the challenged urine samples were collected for analysis by flame photometer of excretion of sodium and potassium at the time zero and after 2 hours of treatment. As a result we found that treatment with paroxetine in rats with AR determined an improvement in fractional shortening (shortening fraction: 52.7 ± 2.2% vs. RA ...
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From its foundation until nowadays, the city of São Paulo has undergone major transformation processes, one of the responsibles for these changes is the presence of efficient transportation ; From construction of roads and routes for the animal traction transportation, railroads, expansion and improvements to the introduction of the automobiles, highways, subway system, among others, all these changes are related to greater flow of people and goods. However nowadays has been reflected issues such as quality of life and development of society in a sustainable way, once we have the construction and reconstruction of space in benefit of capital, and therefore the valuation of individual motorized transport. The overuse of individual motor vehicles are generating an urban chaos, making it increasingly difficult to transit in big cities, the use of bicycles is presented as a viable modal alternative, allowing the flow, and enhancing the health of society and quality of the air
Resumo:
Germline mutations in TP53 gene are associated with Li-Fraumeni syndrome (LFS) and its variants Li-Fraumeni-like (LFL). They predispose carriers to a wide variety of early onset tumors. In Brazil, there is a high frequency of a germline mutation in this gene (NC_000017.9: c.1010G>A; p.R337H) in Southern and Southeastern regions, due to a founder effect. It is estimated to be present in 0,3% ofthe local population, but only few families have been detected. Due to this significant divergence, the purpose of this study was to verify the effectiveness of wider criteria for detection of these individuals. Herein, clinical criteria were established, DNA samples were collected, analyzed by Restriction Fragment Length Polymorphism (RFLP) and sequenced. Thus, assessing the prevalence of this mutation in families with multiple cases of cancer. Based on our proposed criteria, one out of 31 patients (3,22%) was found to carry p.R337H mutation. The patient developed ductal invasive breast cancer at age 47, invasive adenocarcinoma of the lung at age 48 and soft-tissue sarcoma at age 49. In addition, an extensive cancer family history was referred, atypical for LFS, including a case of Ewing’s sarcoma. These outcomes indicate that the proposed criteria may detect probable carriers who did not fit previous LFS criteria. Nevertheless, additional studies, which might include a larger number of families and more stringent parameters, will be useful to improve screening sensibility
Resumo:
Objective: To evaluate if the total bacterial count of vaginal samples with bacterial vaginosis assessed by flow cytometry influences the response to treatment with metronidazol. Methods: In this cross-sectional study, 273 low-risk reproductive aged women were enrolled. Vaginal samples were taken to evaluate the pattern of vaginal flora according to Nugent’s criteria, as well as the presence of trichomoniasis and candidosis. Cases identified of bacterial vaginosis were treated with metronidazole and controlled after 45 days. Cervical infection by Chlamydia trachomatis and Neisseria gonorrhoeae were also assessed. Flow cytometry for total bacterial counting was performed in propidium iodide stained cervicovaginal samples, using fluorescent beads at a known concentration. Non-parametric Mann-Whitney test was used to compare total bacterial count between groups of interest, at p<0.05. Results: From the total of 273 women enrolled, 50 were excluded as they presented at least one of the infections investigated. Bacterial vaginosis was detected in 79 women (35.4%), of which 33 (41.8%) returned for re-evaluation after treatment, being 21 cases successfully treated and 12 with persistent abnormal vaginal flora. Flow cytometric data showed that total bacterial counting does not differ between normal flora and bacterial vaginosis samples (p=0.14). Also, no difference was found between the cases of treated and persistent bacterial vaginosis (p=0.48). Conclusion: Total bacterial counting does not influence the response to metronidazole treatment of bacterial vaginosis
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One of the ways of Geography is the study of the relationship between man and space, so that the question of the preservation of the environment and yours attributes is increasingly standing out in society. The State Forest Edmundo Navarro de Andrade is a conservation of sustainable use, so with this category aims to reconcile nature conservation with sustainable use of a portion of its resources, and a place that has many direct and indirect benefits to the interconnected environment . Therefore, the object of study is the State Forest Edmundo Navarro de Andrade, highlighting its Public Use Area. This work has as main objective to measure the importance of the State Forest Edmundo Navarro de Andrade, in the view of visitors, and present some key aspects of the unit in relation to its attractions. Thus, we seek the appreciation of the history of the city of Rio Claro and qualities of the State Forest Edmundo Navarro de Andrade
Resumo:
Patients that are mechanically ventilated in ICUs are constantly exposed to different pathogens, which present multiantibiotic resistance. Among these microorganisms, is MRSA (Meticillin-Resistant Staphylococcus aureus) considered to be a therapeutic challenge due to its resistance to β-lactam antibiotics. Therefore, this study proposed to identify species of Staphylococcus spp. isolated from mechanically ventilated patients in ICU, the gene mecA detection and the genes of the enterotoxins A (sea), B (seb), C (sec-1) and D (sed) in samples of S. aureus, as well as the phenotypic resistance determination to oxacillin using the disc-diffusion method with discs of oxacillin and cefoxitin. The samples collection occurred during in a period of 19 months, obtaining samples from 232 patients. A percentage of 39% (70) of Gram-positive cocci were found; which 82,8% (58) were identified as Staphylococcus spp,. among these, 75,8% (44) corresponded to S. aureus species and 47,7% were identified as MRSA. It was found resistance to both drugs in 31,8% of the S. aureus samples, 16 (36,3%) had the gene sea and 11 (25%) had the sec-1 gene. Among the coagulase-negative staphylococci obtained, the species most found was S. epidermidis, corresponding to 43% (6). The results revealed that one of the most important etiologic agents of VAP amid the Gram-positive cocci is the species S. aureus, with special attention to MRSA. The presence of enterotoxins genes in S. aureus did not showed determinant role in VAP, but the presence of these superantigens can contribute worsening the patient’s prognosis, since they are associated with intense inflammatory response
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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
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Some of the factors that help to explain the Israeli success case on promoting high-tech start-ups backed by venture capital funds can be found in the risk-taking culture of the country, the vast technological know-how associated with the huge military development, the high offer of human intellectual capital due to the immigration processes, and finally also the FDI inflows, mainly from the United States. Even though, these factors would not have the same effects in the economy unless the right structures were founded by the public-private sectors partnerships for the high-tech industry development and the adaptation of the investment industry surpasses two of the deepest global financial crisis: the dot-com bubble in the 2000’s and the subprime in 2008
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The current study has aimed to analyze changes in strategies at the International Monetary Fund that occurred during the 1980s and 1990s. The analysis is done through the the recovery of the 1980s international economic scene, amid the global recession and debt crisis, and shows how the course of the decade and influenced changes under recommendations provided by the IMF to countries with balance of payments crisis. Furthermore, the paper also describes the changes in the international financial system, in some countries which have adopted them and also to the International Monetary Fund itself
Resumo:
The discovery of neurogenesis in adult brains opened the possibility of cellular therapy strategies for the treatment of neurodegenerative diseases, such as Alzheimer’s disease. Neurogenesis in the adult brain occurs in two areas: subgranular zone of the hippocampus and subventricular zone (SVZ) of the lateral ventricles. Neurons that originate from the SVZ migrate to the olfactory bulb (OB) through the rostral migratory stream (RMS). In Alzheimer’s disease, there is a progressive neuronal dysfunction and degeneration, resulting in brain atrophy and cognitive impairments including olfactory dysfunction. Several studies have demonstrated that pharmacological treatment with lithium exerts positive effects on adult neurogenesis, and one pathway seems to be the modulation of factors that regulate the migration of neuroblasts. The objective of this study was to investigate whether treatment with lithium promotes the increase of migratory neuroblasts using as parameter the RMS. Adult male C57BL/6 mice were divided into control and lithium-treated groups. The animals were treated for 6 weeks and, at four different time points, i.e., 10 days, 7 days, 3 days and 1 day before the end of treatments, they received an injection of BrdU (cell proliferation marker). The animals were sacrificed by perfusion fixation and the brains were immunohistochemically labeled for BrdU for analysis of migrating neuroblasts in the RMS. The results showed that the number of BrdU+ cells in the RMS was not significantly different between the two groups, suggesting that lithium, alone, is not capable of increasing the number of neuroblasts migrating from the SVZ to the OB
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)