Dor: aspectos atuais da sensibilização periférica e central

JUSTIFICATIVA E OBJETIVOS: As pesquisas recentes têm focalizado a plasticidade bioquímica e estrutural do sistema nervoso decorrente da lesão tissular. Os mecanismos envolvidos na transição da dor aguda para crônica são complexos e envolvem a interação de sistemas receptores e o fluxo de íons intracelulares, sistemas de segundo mensageiro e novas conexões sinápticas. O objetivo deste artigo foi discutir os novos mecanismos que envolvem a sensibilização periférica e central. CONTEÚDO: A lesão tissular provoca aumento na resposta dos nociceptores, chamada de sensibilização ou facilitação. Esses fenômenos iniciam-se após a liberação local de mediadores inflamatórios e a ativação de células do sistema imune ou de receptores específicos no sistema nervoso periférico e central. CONCLUSÕES: As lesões do tecido e dos neurônios resultam em sensibilização de nociceptores e facilitação da condução nervosa central e periférica.

Teologia da Libertação e Cultura Política Maia Chiapaneca: o Congresso Indígena de 1974 e as raízes do Exército Zapatista de Libertação Nacional

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Clamores da luta pela terra: Igreja e trabalhadores na busca da transformação social

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Vozes de Morazán: mulheres, resistência e organização popular

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Entre vanguarda e a participação: a democracia no programa político da esquerda brasileira (1930-1935)

This paper examines the conceptions of democracy in the Brazilian left among 1930-1935, in particular those expressed in the manifestos of the National Liberative Alliance (ANL) and the texts written by Luis Carlos Prestes, Virgínio Santa Rosa and Caio Prado Jr. I argue that the Brazilian left started from a common troubled field, according to which land concentration represented the biggest obstacle to genuine political expression of the Brazilian people. Despite the convergence towards land reform, designed as a sine qua non condition to democracy in Brazil, the left has developed two different answers to the practical implementation of the principle of the people's government: the first, which I call altruist vanguard, which is more emphasized on texts of Virgínio Santa Rosa and Luís Carlos Prestes, and the second, the Republican participacionismo, which is explored on the writings of Caio Prado Jr. and ambiguously in the manifests of the National Liberative Alliance.

El Salvador: da guerra civil às reformas institucionais dos anos 1990

Pós-graduação em História - FCHS

Karyotype of the invasive species Pterois volitans (Scorpaeniformes: Scorpaenidae) from Margarita Island, Venezuela

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Acupuncture as therapeutic resource in patient with bruxism

Bruxism is the harmful habit of clenching or grinding the teeth during the day and / or night, with unconscious pattern, with particular intensity and frequency, outside the functional movements of chewing and swallowing. It is accepted that bruxism is a response controlled by the neurotransmitters dopamine system associated with emotional component. The proposed of treatment of bruxism with acupuncture aims to stimulate sensory fibers of the peripheral nervous system leading to electrical transmission by neurons sufficient to produce changes in the central nervous system. As a consequence there is the release of substances (cortisol, endorphins, dopamine, noradrenaline and serotonin) that promote wellness and restoration of harmony, be it psychological, biological and / or behavioral.

Atuação do interferon-tau no reconhecimento materno da gestação

Maternal recognition of pregnancy is a process by which the conceptus signals its presence to the mother in order to prolong the life of the corpus luteum (CL) thus maintaining the pregnancy. This process occurs between days 15 and 19 after fertilization and is the most important biological challenge for obtaining satisfactory reproductive indices in bovine. Interferon-tau (IFN-τ) glycoprotein -secreted in the uterus by the conceptus- has a paracrine action inhibiting the expression of estrogen receptors (ESR1) and oxytocin (OXTR) in the endometrium, thus preventing the release of luteolytic pulses of prostaglandin F2 alpha (PGF2α), hormone responsible for the onset of luteolysis. IFN-τ also increases the expression of several interferon-stimulated genes (ISGs) in the uterus, CL, and blood cells. Direct endocrine action of IFN-τ on extrauterine tissues stimulates ISGs expression, which in the corpus luteum seems to be involved with luteal resistance to luteolytic action of PGF2α. This review discusses recent findings on the luteolysis mechanism in the bovine and endocrine and paracrine mechanisms such as IFN-τ during the maternal recognition of pregnancy.

A periferia de “nosotros”. O debate sobre o documentarismo na América Latina: uma análise do filme La Hora de los hornos (1968)

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

La formación de personalidades éticas: representaciones de sí y moral

The article presents the studies of a current investigation among 75 adolescents from 12 to 15 years old, students of private schools of Campinas city, that have as main objective to notice a possible correspondence among the moral judgements and the representation that individuals have about themselves. From the feeling of admiration the studies bring out the representations of these individuals and answer a questioning if they would have an ethics character or not and if these would correspond to their moral judgements. The results point out to a correspondence among those whose representations of themselves are characterized by more evolved ethics contents and judgements as for sensitivity to the feelings of the characters involved in the situations described. Such studies validate the intention of this article to discuss the correspondences between ethics (how the individual sees himself/herself) and moral (how he/she judges the moral of the situations).

Estudio histológico del processo de reparación alveolar después de la aplicación tópica de la solucioón anestésica prilocaína 3 % con felipressina o,o3 ui/ml

The aim of this study was to evaluate the local anesthetic solution, composed by Prilocaine 3% and felipressin 0,03 UI/ml, influence on the alveolar repair process in rats after dental extraction. This research was previously approved by the Ethic Committee in Research of the Masters Degree Program in Oral and Maxillofacial Surgery of the Marília University (UNIMAR), Marília, São Paulo, Brazil. It was an experimental, randomly controlled study, with bifactorial analysis (group control versus experimental group, in function of the postoperative times (2 X 4)). For the accomplishment of this study 32 rats were used (Rattus norvegicus, albinus, Wistar), males, adults, weighing between 280 and 320 grams. The animals were selected and divided into Group I (control) and Group II (Citocain 3%® - Prilocaine 3% with felipressin 0,03UI/ml) with 16 rats each; being four animals of the Group I and four of the Group II, destined to the euthanasia in the postoperative periods of 3rd, 7th, 15th and 24th days. The histological analysis with base in the developed methodology, allowed us to conclude that the anesthetic solution of Citocain 3%® applied with gauze compress on the surgical dental wound, produced tissue events that committed the basic biological principles, that are responsible for the regeneration of the gingival epithelium and the alveolar process repair in rats. The Group I presented better results in the alveolar repair when compared to the Group II.