16 resultados para Dret-Castella (regne)-S.XIII-Legislació
em Repositório Institucional UNESP - Universidade Estadual Paulista "Julio de Mesquita Filho"
Resumo:
A partir da consideração do mais importante exemplar da hagiografia medieval, a Legenda aurea do dominicano Jacopo de Varazze, o texto pretende discorrer sobre os diversos níveis de erudição dos clérigos cristãos no século XIII e sua importância para a consideração das fontes documentais do período.
Resumo:
A mutation in the factor XIII gene (FXIII Val34Leu) gene was recently reported to confer protection against myocardial infarction, but its relationship with venous thrombosis is unknown. In addition, a mutation in the 5'-untranslated region of the FXII gene (46 C→T) was identified which is associated with low plasma levels of the protein. Its prevalence in patients with venous thrombosis is also unknown. We investigated the frequency of the FXIII Val34Leu and FXII 46 C→T mutations in 189 patients with deep venous thrombosis and in 187 age-, gender- and race-matched controls. FXIII Val34Leu was detected in 38.6% of the patients and in 41.2% of the controls. Interestingly, homozygosity for the FXIII mutation was found in 1.6% of the patients and in 9.6% of the controls. yielding an odds ratio (OR) for venous thrombosis of 0.16 (95% CI: 0.05-0.5). The OR for heterozygotes was 1.1 (95% CI: 0.7-1.7). The FXII 46 C→T mutation was detected in 46.0% of the patients and in 48.6% of the controls. The OR for heterozygotes was 0.9 (95% CI: 0.6-1.4) and for homozygotes the OR was 0.8 (95% CI: 0.3-1.9). Our data indicate that the FXII 46 C→T mutation is unlikely to be a major risk factor for venous thrombotic disease. In contrast, the homozygous state for FXIII Val34Leu is a strong protective factor against venous thrombosis, which emerges as a novel generic factor involved in the aetiology of thrombophilia.
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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Pós-graduação em História - FCLAS
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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Pós-graduação em História - FCLAS
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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A proposta do presente livro é oferecer ao leitor uma descrição fonológica das qualidades vocálicas vigentes na primeira fase (período trovadoresco) do português arcaico a partir da análise das rimas e da grafia das Cantigas de Santa Maria, de Afonso X, o Sábio, Rei de Leão e Castela, elaboradas na segunda metade do século XIII.
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Pós-graduação em História - FCHS
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This work aims to obtain a phonological description of unstressed word-final vowels of Medieval Portuguese (MP). The corpus of this research is comprised of Alfonso X’s Cantigas de Santa Maria, composed on the second half of the 13th century. This work maps all the graphemes that represent, in the corpus considered, the unstressed word-final vowels. From the analyses of writing and rhymes in Alfonso X’s Cantigas de Santa Maria, it was possible obtain some important information about the realization of the unstressed wordfinal vowels in MP.
Resumo:
Pós-graduação em História - FCHS