Orientações nacionais para a reforma do ensino médio: dogma e liturgia

O estudo analisa criticamente os fundamentos das atuais diretrizes nacionais para o ensino médio brasileiro, dando especial enfoque à sua coerência com tendências mundiais e seus nexos com recomendações de agências internacionais para reformas educativas nos países emergentes. Discute, outrossim, as vicissitudes e peculiaridades do processo de formulação das referidas diretrizes e sugere o aprofundamento da discussão, indicando aspectos polêmicos que merecem maior reflexão.

It only takes one to do many jobs: Amphotericin B as antifungal and immunomodulatory drug

Amphotericin B acts through pore formation at the cell membrane after binding to ergosterol is an accepted dogma about the action mechanism of this antifungal, and this sentence is widely found in the literature. But after 60 years of investigation, the action mechanism of Amphotericin B is not fully elucidated. Amphotericin B is a polyene substance that is one of the most effective drugs for the treatment of fungal and parasite infections. As stated above, the first mechanism of action described was pore formation after binding to the ergosterol present in the membrane. But it has also been demonstrated that AmB induces oxidative damage in the cells. Moreover, amphotericin B modulates the immune system, and this activity has been related to the protective effect of the molecule, but also to its toxicity in the host. This review tries to provide a general overview of the main aspects of this molecule, and highlight the multiple effects that this molecule has on both the fungal and host cells. © 2012 Mesa-Arango, Scorzoni and Zaragoza.

Política e democracia em Steban Echeverría (1830-1851)

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

A dramaturgia de Dea Lohe na peça Inocência: o hibridismo teatral na cena contemporânea

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Avaliação mitocondrial em células mononucleares periféricas caninas infectadas com o vírus da cinomose

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Dramaturgia de Dea Loher na peça Inocência: o hibridismo teatral na cena contemporânea

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

A autoafirmação de um Bispo: Gregório de Nissa e sua visão condenatória aos Eunomianos (360-394 d.C.)

Pós-graduação em História - FCHS

A crença religiosa sob a perspectiva semiótica de Peirce

Current paper presents the relationships between beliefs, specifically religious ones, and the Peirce’s theory of interpretants. It is assumed that religious belief emphasizes the emotional aspect of faithful, preventing criticism and change of habit. According to the author, the nature of cognition is contrary to the determination of this kind of belief since it is based on the method and fallibility of hypotheses. It is not enough for the method to deduce its consequences but seeks the inductive verification of their results in the long run and through the community of beings who thinks through signs. The problem of religious belief is the acceptance of a transcendent world and intuition which guides behavior. The vague idea of God is not submitted to scientific hypotheses but, engendered by religious systems, it creates signs whose emotional appeal is evident, redirecting it to its own target principles. Therefore, is repeats the success achieved in the past by dogmas, which were effective to appease the anguish of the believer and reproduce order. Knowledge should not have any boundaries because it is grounded on the method and cognition of reality.