Role of protease-activated receptor-2 in inflammation, and its possible implications as a putative mediator of periodontitis

Proteinase-activated receptor-2 (PAR2) belongs to a novel subfamily of G-protein-coupled receptors with seven-transmembrane domains. This receptor is widely distributed throughout the body and seems to be importantly involved in inflammatory processes. PAR2 can be activated by serine proteases such as trypsin, mast cell tryptase, and bacterial proteases, such as gingipain produced by Porphyromonas gingivalis. This review describes the current stage of knowledge of the possible mechanisms that link PAR2 activation with periodontal disease, and proposes future therapeutic strategies to modulate the host response in the treatment of periodontitis.

Apoptosis as a mediator of hyperplastic recovery in human prostate lesions: cytochemical and immunocytochemical evaluation

The present study was carried out to investigate the occurrence of apoptosis in human prostatic lesions with emphasis on nodular hyperplasia and adenocarcinomas, using cytochemistry and immunocytochemistry. The results showed that apoptosis is a common event on nodular hyperplasia but not in adenocarcinomas. This led to the hypothesis that apoptosis may represent an important factor on the localized recovery response of the hyperplastic acini.

De artista a designer: Alexandre Wollner e o pensamento concreto na construção do design visual no Brasil

Pós-graduação em Artes - IA

Aprendizado baseado em problemas, um novo conceito para a formação do designer e a sustentabilidade

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

O designer e a prática profissional na indústria automobilística no Brasil

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Recombinant disintegrin targets alpha(v) beta(3) integrin and leads to mediator production

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Citral and eugenol modulate DNA damage and pro-inflammatory mediator genes in murine peritoneal macrophages

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Identidade visual e sua relação com a linguagem não verbal

The visual identity is based on a semantic relationship of several signs that make up a coherent system. A bimédia language formed by text and image complement to create an understandable message. This study aims the use of non-verbal communication in the corporate visual identity design project, contextualizing the role of the designer as mediator for informational corporate message to their audiences.

O papel do designer contemporâneo a partir das contribuições europeias na formação do profissional

This article presents a reflection on the profession of designer from the historical period for the pre-industrial revolution approaching the figure of the industrial designer in France and emphasizes the special attention given to it in England as the focus of the Industrial Revolution. Deals with some of the changes that the designer profession suffered along the way, that these changes occur in parallel to social, economic, technological. This study also reflects on the role of the professional in contemporary society and the challenges facing the profession.

Pollination of Anemopaegma album (Bignoniaceae) with focus on floral nectar as the mediator of interactions with mutualistic and antagonistic bees

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)