4 resultados para Common goal

em Repositório Institucional UNESP - Universidade Estadual Paulista "Julio de Mesquita Filho"


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Stemming from in vitro and in vivo pre-clinical and human models, tissue-engineering-based strategies continue to demonstrate great potential for the regeneration of the pulp-dentin complex, particularly in necrotic, immature permanent teeth. Nanofibrous scaffolds, which closely resemble the native extracellular matrix, have been successfully synthesized by various techniques, including but not limited to electrospinning. A common goal in scaffold synthesis has been the notion of promoting cell guidance through the careful design and use of a collection of biochemical and physical cues capable of governing and stimulating specific events at the cellular and tissue levels. The latest advances in processing technologies allow for the fabrication of scaffolds where selected bioactive molecules can be delivered locally, thus increasing the possibilities for clinical success. Though electrospun scaffolds have not yet been tested in vivo in either human or animal pulpless models in immature permanent teeth, recent studies have highlighted their regenerative potential both from an in vitro and in vivo (i.e., subcutaneous model) standpoint. Possible applications for these bioactive scaffolds continue to evolve, with significant prospects related to the regeneration of both dentin and pulp tissue and, more recently, to root canal disinfection. Nonetheless, no single implantable scaffold can consistently guide the coordinated growth and development of the multiple tissue types involved in the functional regeneration of the pulp-dentin complex. The purpose of this review is to provide a comprehensive perspective on the latest discoveries related to the use of scaffolds and/or stem cells in regenerative endodontics. The authors focused this review on bioactive nanofibrous scaffolds, injectable scaffolds and stem cells, and pre-clinical findings using stem-cell-based strategies. These topics are discussed in detail in an attempt to provide future direction and to shed light on their potential translation to clinical settings.

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This work aims to reflect on organizational communication and integrated communication, focusing on the performance of professional Public Relations and Marketing. As a case of study, we evaluated the communication in the BOM DIA journal, especially with regard to the implementation of the Project 50k, dedicated to reviving the journal, with shares of advertising, editorial and structural as well as marketing and sales. The goal is to evaluate the reality of a company, which represents an integrated communication, in which all professionals in various areas and departments within the organization are able to develop a more concise and to seek a common goal, working and developing its workforce which reflects his image and therefore in your external audience

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)