Prevalence of dementia in Latin America: a collaborative study of population-based cohorts

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

PGCP - Plataforma para Gerenciamento Colaborativo de Projetos

Collaborative Systems are designed to support individuals in order to solve a problem together, or cooperatively (or collaboratively). Such systems have the advantage of not requiring the presence in the same location of the participants. The basis of any Collaborative System is communication, where users interact with each other in order to exchange information. Communication among individuals is accomplished through collaborative tools such as chat, email, document repository, etc.. Using these tools, companies can reduce operational costs, saving on travel and accommodation of its employees to attend meetings. The project members only need a computer with internet access to use collaborative tools. Project management is essential to the quality of the nal product. To perform a proper management, methodologies must be applied using methods, tools and procedures. There are some phases that are considered generic for all software process models, they are: de nition, development, maintenance and activity to support the software process. In this paper is described a platform for project management using the concepts and features of Collaborative Systems. The goal of this platform is to unify various collaborative tools (such as chat and document repository) in a project management system. Using the system, it becomes possible to manage projects, and the ability to maintain an active constant communication between members of each project

Pediatric Antiphospholipid Syndrome: Clinical and Immunologic Features of 121 Patients in an International Registry

OBJECTIVES. The purpose of this study was to obtain data on the association of antiphospholipid antibodies with clinical manifestations in childhood and to enable future studies to determine the impact of treatment and long-term outcome of pediatric antiphospholipid syndrome.PATIENTS and METHODS. A European registry extended internationally of pediatric patients with antiphospholipid syndrome was established as a collaborative project of the European Antiphospholipid Antibodies Forum and Lupus Working Group of the Pediatric Rheumatology European Society. To be eligible for enrollment the patient must meet the preliminary criteria for the classification of pediatric antiphospholipid syndrome and the onset of antiphospholipid syndrome must have occurred before the patient's 18th birthday.RESULTS. As of December 1, 2007, there were 121 confirmed antiphospholipid syndrome cases registered from 14 countries. Fifty-six patients were male, and 65 were female, with a mean age at the onset of antiphospholipid syndrome of 10.7 years. Sixty (49.5%) patients had underlying autoimmune disease. Venous thrombosis occurred in 72 (60%), arterial thrombosis in 39 (32%), small-vessel thrombosis in 7 (6%), and mixed arterial and venous thrombosis in 3 (2%). Associated nonthrombotic clinical manifestations included hematologic manifestations (38%), skin disorders (18%), and nonthrombotic neurologic manifestations (16%). Laboratory investigations revealed positive anticardiolipin antibodies in 81% of the patients, anti-beta(2)-glycoprotein I antibodies in 67%, and lupus anticoagulant in 72%. Comparisons between different subgroups revealed that patients with primary antiphospholipid syndrome were younger and had a higher frequency of arterial thrombotic events, whereas patients with antiphospholipid syndrome associated with underlying autoimmune disease were older and had a higher frequency of venous thrombotic events associated with hematologic and skin manifestations.CONCLUSIONS. Clinical and laboratory characterization of patients with pediatric antiphospholipid syndrome implies some important differences between antiphospholipid syndrome in pediatric and adult populations. Comparisons between children with primary antiphospholipid syndrome and antiphospholipid syndrome associated with autoimmune disease have revealed certain differences that suggest 2 distinct subgroups. Pediatrics 2008; 122: e1100-e1107

Incidência de malformações congênitas em crianças concebidas através de injeção intracitoplasmática de espermatozóides

Purpose: to evaluate the incidence and types of major congenital malformations (MCM) in liveborn children conceived by intracytoplasmic sperm injection (ICSI). Methods: a total of 680 liveborn children resulted from 511 couples submitted to ICSI from January, 1999 to December, 2002. Data collection of the children was performed through standardized questionnaire and clinical examination. Of the 511 couples, 366 had been contacted for a sampling of 371 gestations. Of the 680 liveborn, 520 had been evaluated, 250 of them (48.1%) through questionnaire and 270 (51.9%) through questionnaire and physical examination. Two hundred and fifty children were from singleton pregnancies and 270 from multiple pregnancies. Malformations were classified according to the 10th revision of the International Statistical Classification of Diseases and Related Health. Only MCM were analyzed in this study. The incidence of MCM was compared with that of the general population obtained by the Latin American Collaborative Study of Congenital Malformations. The statistical analysis was performed by the χ 2 test (level of significance p<0.05). Results: of the 520 children, 15 presented MCM, resulting in an incidence of 2.9%. There was no difference in relation to the control group (p>0.05), which showed 2.6% incidence of MCM. The most frequent malformations were of cardiac origin (four isolated and two associated), corresponding to 40% of the total. The other types of MCM were: renal (three), neural tube (two), skull (one), cleft lip (one), genital (one), Down syndrome (associated with cardiac malformations) (two), and musculoskeletal (one). Six MCM occurred in children from singleton pregnancies and nine in children from multiple pregnancies. Conclusion: the liveborn children conceived by ICSI presented incidence of major congenital malformations (2.9%) near to the expected for the general population (2.6%). However, to establish the risks of MCM with precision it is necessary to continue the evaluation of the children conceived by ICSI.

The Ped-APS registry: The antiphospholipid syndrome in childhood

In recent years, antiphospholipid syndrome (APS) has been increasingly recognised in various paediatric autoimmune and nonautoimmune diseases, but the relatively low prevalence and heterogeneity of APS in childhood made it very difficult to study in a systematic way. The project of an international registry of paediatric patients with APS (the Ped-APS Registry) was initiated in 2004 to foster and conduct multicentre, controlled studies with large number of paediatric APS patients. The Ped-APS Registry is organised as a collaborative project of the European Forum on Antiphospholipid Antibodies and Juvenile Systemic Lupus Erythematosus Working Group of the Paediatric Rheumatology European Society. Currently, it documents a standardised clinical, laboratory and therapeutic data of 133 children with antiphospholipid antibodies (aPL)-related thrombosis from 14 countries. The priority projects for future research of the Ped-APS Registry include prospective enrolment of new patients with aPL-related thrombosis, assessment of differences between the paediatric and adult APS, evaluation of proinflammatory genotype as a risk factor for APS manifestations in childhood and evaluation of patients with isolated nonthrombotic aPL-related manifestations. © The Author(s), 2009.

Epístola a Os Fofos: artes cênicas, espiritualidade e ciência na 'Festança' Terra de Santo de Os Fofos Encenam

Pós-graduação em Artes - IA

Telejornalismo e interatividade na TV digital: uma construção colaborativa e participativa no espaço digital

Pós-graduação em Televisão Digital: Informação e Conhecimento - FAAC

Estudo das necessidades, planejamento e prognóstico endodôntico em pacientes com fissuras de lábio e/ou palato submetidos ao tratamento cirúrgico

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Trabalho colaborativo entre universidade e escola: proporcionando a formação continuada através da história da biologia

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Acessibilidade em ambientes informacionais digitais

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Acessibilidade em Ambientes Informacionais Digitais

The current nature of World Wide Web (Web), which highlights the collaborative participation of users in some digital information environments, lead to development of guidelines with a focus on Inclusive Digital Information Architecture for a different audiences in multiples informational ambiences. This research proposes guidelines for a inclusive digital information environment, aiming to identify the elements of accessibility that allow the promotion of inclusion digital information, in order to highlight the references of the Architecture of Digital Information, the international recommendations and the structures representation of information (specially accessibility attributes), with the look of Information Science and New Technologies of Information and Communication. The thesis is as to the need to develop methodologies with guidelines that contemplate the elements of digital accessibility focused on the task of the user. The research problem is that actual methodologies and recommendations used for the development of digital information environments do not cover all the elements of accessibility with a focus on user needs. The proposition is to present, through a methodological approach (exploratory and descriptive), a theoretical-methodological proposal to promote elements of digital accessibility to the development of digital information environments, for users with or without special needs. The overall objective of this study is to contribute to the development of inclusive digital information environments, in perspective of union of theories, recommendations and technologies for the development of digital accessibility guidelines. In a theoretical dimension, the research covers a critical review of the specialized literature in the areas of Information Science and Computer Science and, in the applied part, the analysis and development of a proposal of guidelines for the architecture of a digital information environment with accessibility.

A pesquisa em psicologia: ensaio sobre a Psicologia enquanto ciência, a pesquisa qualitativa e o uso da entrevista como principal instrumento de coleta de dados

For constituting itself a science, Psychology has coursed along way. From the time he was considered a Philosophy’s discipline until to be recognized as a legitimate science, Psychology had to devoteto the definition of its object of study, the development and refinement of theoretical-methodological frameworks and, in particular, to consolidation process of their research strategies and knowledge construction. Therefore, in order to regard the demands of the classical scientific paradigm, which is very influenced by Positivism, Psychology made use, initially, of quantitative methodology and laboratory research. This article presents some of the process of identity construction of Psychology as a science, focusing on its transition path between the quantitativist paradigm of scientific knowledge production to the qualitativist paradigm, until that is more commonly practiced nowadays: the collaborative use of these methodological strategies. For presenting the qualitative researching Psychology, we discussed, beyond its proposal and differentiation elements in relation to quantitative research, the different methods used for this mode and, in particular, the interview - which is considered the main way of data collection in surveys conducted by psychologists and, therefore, it is an important element the process of knowledge building that science, in addition to being the most qualified space for dialogue between there searcher and the research subject.

Pertencer e deslocar virtualmente: Teletandem como espaço antropofágico

Pós-graduação em Estudos Linguísticos - IBILCE