Detection of cytokines and nitric oxide synthase in skin lesions of Jorge Lobo's disease patients

Studies investigating the immunopathological aspects of Jorge Lobo's disease have shown that the inflammatory infiltrate consists mainly of histiocytes and multinucleated giant cells involving numerous yeast-like cells of Lacazia loboi, with the T lymphocytes more common than B lymphocytes and plasma cells. The quantification of cytokines in peripheral blood mononuclear cells culture supernatant has revealed alterations in the cytokines profile, characterized by predominance of a Th2 profile. In view of these findings and of the role of cytokines in cell interactions, the objective of the present study was to investigate the presence of the cytokines IL-10, TGF-ss 1 and TNF-alpha, as well as iNOS enzyme in granulomas induced by L. loboi. Histological sections obtained from skin lesions of 16 patients were analyzed by immunohistochemistry for the presence of these cytokines and iNOS. The results showed that TGF-ss 1 was the cytokine most frequently expressed by cells present in the inflammatory infiltrate, followed by IL-10. There was a minimum to discrete positivity of cells expressing TNF-alpha and iNOS. The results suggest that the presence of immunosuppressive cytokines in skin lesions of patients with the mycosis might be responsible for the lack of containment of the pathogen as demonstrated by the presence of numerous fungi in the granuloma.

Búsqueda de nuevas rutas comerciales. Solón Wilches y las redes de poder en García Rovira, segunda mitad del siglo xix

This article presents a project formulated by the president of the Sovereign State of Santander, Solon Witches, to open new trade routes in order to create and maintain a network of power in the department of Garcia Rovira. First, the text highlights the political activity of General Witches to help his region; second, the commercial activities which surrounded his network of friends and family. Finally, the text answers the question of how associations worked around a main character in order to complete commercial transactions in a specific region.

Permanent Genetic Resources added to Molecular Ecology Resources Database 1 December 2012-31 January 2013

This article documents the addition of 268 microsatellite marker loci to the Molecular Ecology Resources Database. Loci were developed for the following species: Alburnoides bipunctatus, Chamaerops humilis, Chlidonias hybrida, Cyperus papyrus, Fusarium graminearum, Loxigilla barbadensis, Macrobrachium rosenbergii, Odontesthes bonariensis, Pelteobagrus vachelli, Posidonia oceanica, Potamotrygon motoro, Rhamdia quelen, Sarotherodon melanotheron heudelotii, Sibiraea angustata, Takifugu rubripes, Tarentola mauritanica, Trimmatostroma sp. and Wallago attu. These loci were cross-tested on the following species: Alburnoides fasciatus, Alburnoides kubanicus, Alburnoides maculatus, Alburnoides ohridanus, Alburnoides prespensis, Alburnoides rossicus, Alburnoides strymonicus, Alburnoides thessalicus, Alburnoides tzanevi, Carassius carassius, Fusarium asiaticum, Leucaspius delineatus, Loxigilla noctis dominica, Pelecus cultratus, Phoenix canariensis, Potamotrygon falkneri, Trachycarpus fortune and Vimba vimba. © 2013 Blackwell Publishing Ltd.

Doença de Jorge Lobo e sua relação com os antígenos do sistema HLA

Pós-graduação em Doenças Tropicais - FMB

O simbolismo na poesia de Jorge de Lima

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

A formação do tecido discursivo em A Árvore das palavras, de Teolinda Gersão, e em A Manta do soldado, de Lídia Jorge

Pós-graduação em Estudos Literários - FCLAR

Traços romanescos e épicos em Jubiabá de Jorge Amado

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Os jesuítas e a escravidão africana no Brasil colonial: um estudo sobre os escritos de Antonio Vieira, André João Antonil e Jorge Benci: sécs. XVII e séc. XVIII

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Jorge Amado e a consciência discursível em A morte e a morte de Quincas Berro D'água

Pós-graduação em Letras - FCLAS

O leitor nas trilhas do texto: um diálogo entre a teoria de Umberto Eco e a poética da leitura de Jorge Luis Borges

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

A metamorfose seniana: poesia e crítica na obra de Jorge de Sena

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Afinidades eletivas entre as obras de García Márquez e Escher

Este trabalho pretende mostrar as ligações entre um texto verbal, o conto “A terceira renúncia”, de Gabriel Garcia Márquez e os textos visuais: “Unicórnios”, “Pássaros”, “A fita de Moebius II” e “Um outro mundo II”, de Maurits Cornelis-Escher. Palavras-chave: Fratura; figuralidade; estesia; figuratividade.

De autor a personagem: Jorge Luis Borges na mira de romancistas latino-americanos

Pós-graduação em Letras - FCLAS

Construção da memória a partir dos lugares, instituições e documentos: um estudo do Centro de Documentação e Memória Pe. Antão Jorge do Santuário Nacional de Aparecida

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)