The in vitro antiviral activity of an aliphatic nitro compound from Heteropteris aphrodisiaca

We investigated the antiviral activity of an aliphatic nitro compound (NC) isolated from Heteropteris aphrodisiaca O. Mach. (Malpighiaceae), a Brazilian medicinal ptant. The NC was tested for its antiviral activity against poliovirus type 1 (PV-1) and bovine herpes virus type 1 (BHV-1) by plaque reduction assay in cell culture. The NC showed a moderate antiviral activity against PV-1 and BHV-1 in HEp-2 celts, and the 50% inhibitory concentration (IC50) were 22.01 mu g/ml (selectivity index (SI) = 2.83) and 21.10 mu g/mi (SI = 2.95), respectivety. At the highest concentration of the drug (40 mu g/ml) a reduction of approximately 80% in plaque assay was observed for both viruses. The treatment of cells or virus prior to infection did not inhibit the replication of virus strains. (C) 2006 Elsevier GmbH. All rights reserved.

Excalibur: uma perspectiva pagã sobre a lenda de Excalibur

This work tries to show to the reader a more mystical side of Excalibur and its importance to the Arthurian myth. As its origin is pagan indigenous to the legends of the Celtic people, they will be briefly introduced to the reader so that they can realize the time in which the Celts lived, who they were and a little about how they acted in accordance with their culture . It will also be exposed a brief overview about the character of King Arthur and all the changes that it has passed through according to what suited to the culture of each time. Two legends about Excalibur will be analyzed, so that both points of view Pagan and Christian can be disclosed according to the myths and theoretical texts used as a basis for this work. Finally, several analyzis about the sword will be brought to the reader so they can understand the complexity of myths and symbols that the Celts have left as a legacy