Microemulsões: Estrutura e aplicações como sistema de liberação de fármacos

Depending on formula composition, microemulsions may be used as a vehicle for drug administration. In this work the main applicable parameters used in the development of pharmaceutical microemulsions (ME) are analyzed. The conceptual description of the system, theoretical parameters related to formation of internal phases and some aspects of ME stability are described. The pseudo ternary phase diagram is used to characterize ME boundaries and to describe different structures in several regions of the diagram. Some applications of ME as drug delivery systems for different administration routes are also analyzed. ME offer advantages as drug delivery systems, because they favor drug absorption, being in most cases faster and more efficient than other methods in delivering the same amount of drug.

Verbos em movimento em inglês: uma proposta de descrição e ensino por meio do modelo de integração conceptual

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

A utilização do Resource Description and Access (RDA) na criação de registros de autoridade para pessoas, famílias e entidades coletivas

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Integração conceptual na descrição de fenômenos gramaticais do português

Functional grammar currently has a great acceptance in linguistics, mainly because it can enlighten grammatical facts' motivation in the structure of a text. From its emergence, the tradition of studying grammar by grammar has come to an end. Demonstrative pronouns, for instance, have begun to be viewed as efficient tools of text cohesion, used to resume terms from previous clauses. This task, however, ends up leaving an endless trail of black boxes. How is it possible to explain the origin of demonstratives' anaphoric functioning if they are originally used to indicate things or people relative to the interlocutors' spatial position? This work aims at showing that Cognitive Linguistics arises just as an option for opening those black boxes. This article focuses on one of its themes - the conceptual blending theory - to support this possibility. Firstly, it was necessary to integrate the cognitive model into the complexity theory, according to Bybee (2010) and Castilho (2009), who understand language as a complex adaptive system. After that, a brief updated description on the conceptual blending theory is made and its application in some grammatical facts of the Brazilian Portuguese language is suggested under the morphological and syntactic levels.