Avaliação da densidade vascular pelo CD-34 no carcimona ductal in situ da mama comparando os tipos comedo e não comedo

Pós-graduação em Ginecologia, Obstetrícia e Mastologia - FMB

Histopathologic Changes Induced by Intense Pulsed Light in the Treatment of Poikiloderma of Civatte

Background The clinical efficacy of intense pulsed light (IPL) in the treatment of poikiloderma of Civatte (PC) is well documented, but little is known about microscopic changes. Objective To analyze histopathologic findings on the necks of individuals with PC after IPL therapy. Materials and Methods Fourteen patients with PC on the neck underwent three monthly sessions of IPL. Biopsies and clinical photographs were taken before and 60 similar to days after treatment. A dermatopathologist analyzed histopathologic slides stained with hematoxylin and eosin, Masson's trichrome, Verhoeff-van Gieson and Fontana-Masson or processed for CD-34 immunohistochemistry. The slides also underwent digital image analysis. Clinical results were based on the analysis of the pictures by three dermatologists and on patient satisfaction. Results Intense pulsed light treatment resulted in more-homogeneous melanin distribution; a greater number of fibroblasts and nonfragmented elastic fibers; and greater density (p similar to=similar to.01), color intensity (p similar to=similar to.02), number and thickness of the collagen bundles. No significant changes in vessels number or diameters were observed. Clinical results were positive in 92.9% of the cases. Conclusion IPL treatment of PC induced a more-homogeneous distribution of melanin and increased nonfragmented elastic fibers, collagen density, and intensity. These changes were related to clinical improvement.

Orbital solitary fibrous tumor: Report of two cases and literature review

Background: Solitary fibrous tumor (SFT) is a rare, benign, and very uncommon lesion in the orbit. Because of its complex and variable clinical and histological appearance the SIFT is often misdiagnosed.Cases: Two new cases of orbital SIFT are reported, one in a man and the other in a woman, both unilateral and in the superomedial orbit.Observations: Clinical and tomographical evaluations were conducted and the lesions were excised. The histological evaluation showed the tumors were composed of spindle-shaped cells within colla.-en bundles and vascular channels. Immunohistochemical staining was positive for CD 34 and negative for S-100 protein.Conclusion: Immunohistochemical study is an important adjuvant in determining the SIFT diagnosis. Long-term follow-up is necessary because of the possibility of SFT recurrence after excision. (C) 2003 Japanese Ophthalmological Society.

Structural and ultrastructural evidence for telocytes in prostate stroma

The prostate comprises a glandular epithelium embedded within a fibromuscular stroma. The stroma is a complex arrangement of cells and extracellular matrix (ECM) components in addition to growth factors, regulatory molecules, remodelling enzymes, blood vessels, nerves and immune cells. The principal sources of ECM components are fibroblasts and smooth muscle cells (SMC), which synthesize the structural and regulatory components of the ECM. Telocytes (TCs) were recently described as a novel stromal cell type that exhibited characteristic features. The aim of this study was to confirm the presence of TCs in prostate stromal tissue of gerbils, as the stromal compartment of this gland is a dynamic microenvironment. We used transmission electron microscopy (TEM), light microscopy and immunohistochemistry methods to provide morphological evidence for the presence of TCs. Cells that resembled TCs were observed in gerbil prostatic stroma. These cells had small cellular bodies with very thin and extremely long cellular processes. They were found primarily in the subepithelial area and also at the periphery of SMC layers. TCs also exhibited moniliform processes, caveolae and nuclei surrounded by small amounts of cytoplasm. Close contacts between TC podomers were evident, particularly in the adjacent epithelial compartment. This morphological evidence supported the presence of TCs in the gerbil prostatic stroma, which we report for the first time. © 2013 The Authors. Published by Foundation for Cellular and Molecular Medicine/Blackwell Publishing Ltd. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

Avaliação da viabilidade do selante de fibrina derivado de veneno de serpente como arcabouço biológico para células-tronco mesenquimais de medula óssea de ratos

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Isolamento, cultivo, caracterização e criopreservação de células tronco mesenquimais derivadas de membrana amniótica, geléia de Wharton e sangue do cordão umbilical de fetos bovinos

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Avaliação do uso de Selante de Fibrina derivado do veneno de serpente como arcabouço biológico de células tronco mesenquimais na regeneração óssea do fêmur de ratos

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Avaliação da limpeza de CDtrodo construídos a partir de CD de ouro gravável/fita adesiva de galvanoplastia

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Determinação simultânea de 'CD' e 'PB' e de 'CR' e 'NI' em plantas medicinais empregando a espectrometria de absorção atômica com amostragem direta de suspensões

Pós-graduação em Química - IQ

Estudo da labilidade de Cu(II), Cd(II), Mn(II) e Ni(II) em substâncias húmicas aquáticas utilizando-se membranas celulósicas organomodificadas

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Direct determination of Cu, Cd, Ni and Pb in aquatic humic substances by graphite furnace atomic absorption spectrometry

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Enzymatic and structural characterization of new PLA2 isoform isolated from white venom of Crotalus durissus ruruima

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Biochemical dissection of diageotropica and Never ripe tomato mutants to Cd-stressful conditions

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Períodos de interferência das plantas daninhas na cultura da soja nos sistemas de semeadura direta e convencional

A presente pesquisa objetivou estudar os efeitos dos períodos de controle e de convivência de uma comunidade infestante sobre as características produtivas da soja nos sistemas de semeadura direta (SSD), com o cultivar CD 201, e convencional (SSC), com a MSOY-6101. No SSD, a comunidade infestante foi composta principalmente por Alternanthera tenella, Cenchrus echinatus e Bidens pilosa, com densidade máxima de 377 plantas m-2, acumulando 365,7 g m-2 de matéria seca, e, no SSC, por A. tenella, Senna obtusifolia e Panicum maximum, com densidade máxima de 161 plantas m-2, acumulando 406,7 g m-2. Tolerando cinco por cento de perda na produtividade da cultura, constatou-se que os períodos críticos de prevenção da interferência foram dos 33 aos 66 DAE para o cultivar CD 201 no SSD e dos 34 aos 76 DAE para o cultivar M-SOY-6101 no SSC. A interferência das plantas daninhas durante todo o ciclo da cultura reduziu, em média, 46% (SSD) e 32% (SSC) a produtividade de grãos da soja. Não houve efeito das plantas daninhas na estatura das plantas, na altura de inserção da primeira vagem e no número de vagens por planta.

Fractionation of Zn, Cd and Pb in a Tropical Soil After Nine-Year Sewage Sludge Applications

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)