Uso de medicações por via subaracnóidea no tratamento da dor crônica

JUSTIFICATIVA E OBJETIVOS: A dor crônica é um desafio para a Medicina atual. Novos métodos e medicamentos têm sido propostos com o intuito de controlar os sintomas álgicos. A via de administração subaracnóidea tem se mostrado como uma alternativa viável e segura, embora necessite continuamente ser objeto de estudo de muitos pesquisadores. O objetivo deste trabalho é fazer uma revisão dos medicamentos disponíveis no arsenal terapêutico já consagrados pelo uso e os que se mostram promissores na atualidade para a prática clínica diária. CONTEÚDO: Nesta revisão são avaliados vários fármacos que apresentam ação analgésica quando utilizada via neuroeixo. Opióides, anestésicos locais, agonistas alfa2-adrenérgicos, antagonistas dos aminoácidos excitatórios e inibitórios, acetilcolina, inibidores da acetilcolinesterase, bloqueadores dos canais de cálcio, adenosina, serotonina, antidepressivos tricíclicos e inibidores da síntese de prostaglandinas são analisados no que concerne aos seus efeitos farmacológicos, incluindo os indesejáveis. CONCLUSÕES: Muitos avanços foram registrados no controle dos sintomas álgicos após a utilização das substâncias citadas por via raquidiana, onde certamente algumas serão aproveitadas e enriquecerão o arsenal terapêutico e outras relegadas temporária ou definitivamente. Entretanto, ainda serão necessários muitos estudos clínicos e experimentais para que estes conhecimentos possam ser incorporados e utilizados com segurança pelos profissionais que lidam com o tratamento da dor crônica.

El gobierno de las megalópolis, el caso de Brasil, São Paulo: gestión metropolitana, descentralización y participación como desafíos simultáneos

The government of a megalopolis, such as São Paulo, shows singular challenges that do not exist in less complex urban contexts. Being a city of a country with a recent industrialized economy, with an income (functional and geographical) highly concentrated, that has resumed the democracy for only one quarter of a century, this megacity lives with its own political and organizational assignments, due to the contradictory character of the political behavior of its habitants/ voters and of the traditionalist nature of populism and patronage in the relationship between the rulers and the ruled and between the Executive and Legislative powers at the local level. In such context, the difficulties to prosecute the assignments of the metropolitan organization, the decentralization and the institutionalization of citizen participatory channels in the governance and administrative activities are huge. The centrifuge forces (of the decentralization of the local government, through subprefectures), the centripetal forces ( of the metropolitan organization process) and the diffuse forces (of the claiming popular participation) act simultaneously over the deciding processes, in São Paulo, receiving, still, state and national political influences, since the city is a very significant historically producer of political and electoral capital. The analysis of the recent experience of the creation of the subprefectures and the representative counsels (fixed in the Municipality Organic Law of 1990) and the attempt to implement the participatory budgeting, in two occasions (1989-1992 and 2001-2004), reveal some of the social and political reasons that make difficult the establishment of a solidly democratic governance and of a more efficient public administration in the metropolitan area of São Paulo.

Estrutura de conteúdos educativos para TV Digital: um modelo de referência

This paper proposes a model of educative content structuring for interactive digital television programs. Its intent was to provide references for collaborative production processes and content organization in learning networks associated with university and educative television broadcasting services. The model defines terms, actors, events, environments, as well as content categories, classes and attributes, indicating criteria for their synchronic or asynchronic association in a dynamic television schedule. The model is presented in both descriptive and visual formats, with the use of conceptual maps. The results indicate that interactive use of digital television in education requires systematic content models covering communitarian participation in both media production and distribution processes, in order to enhance learning instruments beyond vertical, hierarchical and centralized communication sustained by traditional broadcast channels.

Face paulista da TV digital: reflexão sobre a multiprogramação na TV cultura

The implantation procedure of the multiprogramming for TV Cultura, a station under the responsibility of the Fundação Padre Anchieta,from the regulation of digital television in Brazil, through the Sistema Brasileiro de Televisão Digital Terrestre (SBTVD-T), involves the creation and implantation of multiprogramming channels of the station, the Univesp TV and the Multicultura channels, which are functioning through means of a special authorization in scientific and experimental character. Analyzed from the Communication Politics Economy point of view, this research contributes to the reflexion about the multiprogramming which may create alternatives to new options in this country programming and content.

Mapeamento da comunicação nas organizações bauruenses: verificando o empoderamento da comunicação no interior paulista

The quantitative research conducted on communication in organizations from bauruenses has served as inspiration for: the development of applied research regarding Brazilian organizational reality, to the communication courses and on the improvements in the communication aspect of the organizations in the region. The goal is to provide information related t the role of organizational communication and the public relations role in this process, measuring the empowerment of this community. The mapping methodology is based on structured questionnaires in order to capture ordinary factors, active and retroactive, from the communication processes such as: relationship types, channels and media, degree of interaction and interdependence between the parties; types of public involved in the process and the expectations of the organization in relation to goals, objectives, actions, events and activities programmed in communication. For the delineation of a reflective proposal from the data, we chose to work on analyzing three dimensions: the strategic communication, linked to the business model and information technologies; the internal communication, linked to culture, to the organizational structure and management that implies the new paradigms of relationship; and lastly, the intention to materialize the collected data on indicators and scales from attributes caused or inhibited from the excellent communication, including evaluation of the practice of Public Relations. This article presents the main results related to micro companies in Bauru, São Paulo.

Geoprocessamento de variáveis morfométricas para caracterização da microbacia do Córrego do Petiço

This study aims to perform the morphometric characterization of the watershed stream Petiço, Botucatu-SP, through techniques of GIS by GIS IDRISI Selva and Charter planialtimetric Botucatu (SF-22-ZB-VI-3) , edited by IBGE (1969), scale 1: 50000 for ranking the drainage network and the morphometric analysis. The variables analyzed were the dimensions, the relief pattern, pattern of the drainage network and the shape variables. The results show that related to how the watershed has an oblong shape with environmental interpretation with low tendency to flooding and erosion. The sinuosity index of 1.22 shows that the channels of the micro tend to be somewhat sinuous, which allows to infer that is permeable soil with good water infiltration. Based on the results of the morphometric variables was found that the watershed is in good condition of conservation, however, presents certain risks of susceptibility to erosion, and environmental degradation in some points, being fundamental to the maintenance of vegetation cover, in view of the roughness coefficient (Rn). Thus, the evaluation of morphometric characteristics in the study watershed constitutes an important tool in conjunction with the use of GIS and Geographic Information Systems makes possible the planning and management of natural resources aimed at their conservation.

Variation of soil and water volumes in riparian jungle soils of Brazil

The objective of this work is to study the relation between humidity, density, porosity and shrinkage of the floodplain soil and riparian vegetation and their ability to store water. For this purpose, two locations for every type of soils were evaluated. Both were placed at the Agronomy University (Faculdade de Ciências Agronômicas) in São Manuel, State of São Paulo, Brazil. The floodplain soil was vegetated with Southern Cattail (Typha domingensis). In both places, soil samples were collected from several depths: 0, 30, 60 and 100 cm. Results show that lower soil density values (0.15 g/cm3) with organic texture and high porosities values (up to 86.2%) were found in samples with the highest organic material content in the floodplain soil. For this field experiment, flood plains soils (characterised as basin gley soils) presented high volumetric instability with a retratibility of 67.49% and higher water storage capacities compared to riparian stands soils (characterised as fluvic neosoils).