Synthetic and natural polycations for gene therapy: State of the art and new perspectives

Currently, the major drawback of gene therapy is the gene transfection rate. The two main types of vectors that. are used in gene therapy are based on viral or non-viral gene delivery systems. There are several non-viral systems that can be used to transfer foreign genetic material into the human body. In order to do so, the DNA to be transferred must escape the processes that affect the disposition of macromolecules. These processes include the interaction with blood components, vascular endothelial cells and uptake by the reticuloendothelial system. Furthermore, the degradation of therapeutic DNA by serum nucleases is also a potential obstacle for functional delivery to the target cell. Cationic polymers have a great potential for DNA complexation and may be useful as non-viral vectors for gene therapy applications. The objective of this review was to address the state of the art in gene therapy using synthetic and natural polycations and the latest strategies to improve the efficiency of gene transfer into the cell.

Titanium in Dentistry: Historical development, state of the art and future perspectives

Titanium is a metallic element known by several attractive characteristics, such as biocompatibility, excellent corrosion resistance and high mechanical resistance. It is widely used in Dentistry, with high success rates, providing a favorable biological response when in contact with live tissues. Therefore, the objective of this study was to describe the different uses of titanium in Dentistry, reviewing its historical development and discoursing about its state of art and future perspective of its utilization. A search in the MEDLINE/PubMed database was performed using the terms 'titanium', 'dentistry' and 'implants'. The title and abstract of articles were read, and after this first screening 20 articles were selected and their full-texts were downloaded. Additional text books and manual search of reference lists within selected articles were included. Correlated literature showed that titanium is the most used metal in Implantology for manufacturing osseointegrated implants and their systems, with a totally consolidated utilization. Moreover, titanium can be also employed in prosthodontics to obtain frameworks. However, problems related to its machining, casting, welding and ceramic application for dental prosthesis are still limiting its use. In Endodontics, titanium has been used in association to nickel for manufacturing rotatory instruments, providing a higher resistance to deformation. However, although the different possibilities of using titanium in modern Dentistry, its use for prostheses frameworks still needs technological improvements in order to surpass its limitations. © 2012 Indian Prosthodontic Society.

Some deviations of form: a little essay on psychoanalysis, art and aesthetics

This work intends to investigate the use of psychoanalytical theory within the aesthetic and critical contemporary art field. To this purpose, it focuses on two philosophers who have become significant in our time: the art critic Hal Foster and the art historian Georges Didi-Huberman. This study aims to show how far the concepts generated in psychoanalytic praxis allowed interpretations that disrupt the traditional aesthetics field. This type of analysis is possible once we abandon the paradigm of “applied psychoanalysis”, which is still current in non-clinical setting. Finally, the proposal wants to argue that the category of the amorphous may clarify certain aesthetic experiences that range from the modernity of art through postmodernity.

Arte naïf: da Santa Ceia aos Orixás

Pós-graduação em Artes - IA

Art in the inclusion of children with special needs in dentistry

A proposta deste estudo é relatar a utilização da arte e seus segmentos, como recurso para inclusão da criança portadora de necessidades especiais ao ambiente odontológico. Foi utilizado como método a aplicação da arte em atividades de socioterapia e oficinas, divididas em módulos: sessão de socialização, oficinas de arte e atividades complementares, visando à elaboração de uma anamnese cultural por meio de questionários e a obtenção das preferências artísticas dos 313 participantes, previamente às suas assistências odontológicas no CAOE (Centro de Assistência Odontológica a Portadores de Necessidades Especiais) FOA/Unesp. de acordo com os questionários respondidos, a música e a pintura, segundo a preferência dos participantes, são os segmentos artísticos que mais auxiliam nas atividades de inclusão e adaptação. Concluímos que a utilização da arte na adaptação e inclusão ambiental do paciente, previamente à assistência odontológica, é favorável e eficaz.

Experimental Basis and New Insights for Cell Therapy in Chronic Obstructive Pulmonary Disease

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Mapeamento Mobile Art: propostas poéticas em telefones celulares : de 2001 a 2010

Pós-graduação em Artes - IA

Arte e ética em The Bell de Iris Murdoch

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Uma análise do espiritismo em Fortaleza-CE, com ênfase na expansão territorial do grupo espírita Paulo e Estevão (GEPE), na perspectiva de visibilidade do espaço religioso

Pós-graduação em Geografia - IGCE

Estado da arte sobre sexualidade e educação sexual: estudo analítico-descritivo de teses e dissertações produzidas na Universidade Estadual Paulista

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

A dança como mediadora na formação da criança

This paper analyzes the dance, considered the oldest of the Arts, inserted in Art and Education. When you talk about dance as art, sought to articulate dance, body movement and music, because all these aspects are crucial when it comes to education in dance. Thus, this paper, by analyzing the meaning of dance over time, also made a parallel with the evolution of the concept of body that, throughout history, became the focus of sin, to currently be seen in optical freedom and autonomy, looking up from childhood, the formation of body awareness and embodiment, as a basis for identity and the formation of a positive self-image. In describing the evolution of dance, between different societies, it was shown that the tool is the dancer's own body and that for its use, it is necessary to look at its interior, human vitality, musicality and sensitivity. Proved that dance since the beginning, has been seen as a medium body, as well as desires and deepest sorrows of humanity, linked to religion, ritual or ceremonial, reaching today the freest expression of body, in modern dance. Given these considerations, based on theoretical frameworks, emphasized the importance of dance in middle school, focusing on their educational role and liberating, showing that it must be used as a tool for teaching and learning, and the development of children , given its interdisciplinary character, this Crosscutting Themes in elementary school and early childhood education curriculum benchmark. The paper concludes that, despite legislation and official documents require training for dance in the school curriculum, very little is done in this direction, which shows that there is still a choice of schools, the immobility of the pupils

Mestre Didi: um estudo sobre arte e cultura afro-brasileira

The following study aimed understanding the self-esthetic of the artist-priest Master Didi, doing so a symbolic interpretation of his sculptures, considering his relations with the ritual performance of candomblé, his creative process and his artistic, sociocultural and religious influences. The interpretation of sculptures and comprehension of the process of creation from the artist with focus on the representation of orixás allowed us to evidence the relationship established between the procedures used by the artist to produce his sculptures, the materials used in his work, the relationship of works and religion, with culture and afro-Brazilian art.