Herdabilidades e correlações entre pesos do nascimento à idade adulta em rebanhos da raça Nelore

Dados de 19.458 animais da raça Nelore, nascidos entre 1975 e 2002 e pertencentes a oito fazendas participantes do Programa de Melhoramento Genético da Raça Nelore (PMGRN), foram utilizados para estimar componentes de covariância, herdabilidade e correlações genéticas dos pesos ao nascimento, à desmama, ao sobreano e aos 2, 3 e 5 anos de idade. Utilizou-se o método da máxima verossimilhança restrita, em análises uni, bi e multicaracterísticas, com modelos que incluíram o efeito genético aditivo direto, como aleatório, além dos efeitos fixos de grupo de contemporâneos e os efeitos linear e quadrático da idade do animal à pesagem (com exceção do modelo para peso ao nascer) e da idade da mãe ao parto. O efeito aleatório de ambiente permanente materno também foi incluído nos modelos de análise do peso ao nascer, peso à desmama e peso ao sobreano e o efeito aleatório genético materno somente no modelo do peso à desmama. As herdabilidades estimadas em análise multicaracterística para os pesos ao nascer, à desmama, ao sobreano, aos 2, 3 e aos 5 anos de idade foram 0,25; 0,33; 0,34; 0,32; 0,33 e 0,35, respectivamente. As correlações genéticas estimadas entre os pesos foram positivas e de moderadas a altas magnitudes e tenderam a diminuir com o aumento da distância entre as pesagens, o que indica que a seleção para peso em qualquer idade deverá promover mudança genética nos pesos nas demais idades, inclusive no peso adulto de fêmeas da raça Nelore. As estimativas de herdabilidade obtidas na análise multicaracterística foram superiores, sobretudo para os pesos aos 3 e aos 5 anos de idade, o que sugere melhor partição das variâncias genética e de ambiente em comparação às análises uni e bicaracterísticas, porém a alta demanda de recursos computacionais em análises de muitas características pode ainda dificultar o uso dessas análises em grandes bancos de dados.

Mesh cancer: long-term mesh infection leading to squamous-cell carcinoma of the abdominal wall

Purpose: It is recognized that chronic inflammation can cause cancer. Even though most of the available synthetic meshes are considered non-carcinogenic, the inflammatory response to an infected mesh plays a constant aggression to the skin. Chronic mesh infection is frequently the result of misuse of mesh, and due to the challenging nature of this condition, patients usually suffer for years until the infected mesh is removed by surgical excision. Methods: We report two cases of squamous-cell carcinoma (SCC) of the abdominal wall, arising in patients with long-term mesh infection. Results: In both patients, the degeneration of mesh infection into SCC was presumably caused by the long-term inflammation secondary to infection. Patients presented with advanced SCC behaving just like the Marjolin's ulcers of burns. Radical surgical excision was the treatment of choice. The involvement of the bowel played an additional challenge in case 1, but it was possible to resect the tumor and the involved bowel and reconstruct the abdominal wall using polypropylene mesh as onlay reinforcement, in a single stage operation. He is now under adjuvant chemotherapy. The big gap in the midline after tumor resection in case 2 required mesh bridging to close the defect. The poor prognosis of case 2 who died months after the operation, and the involvement of the armpit, groin and mesenteric nodes in case 1 shows how aggressive this disease can be. Conclusion: Infected mesh must be treated early, by complete excision of the mesh. Long-standing mesh infection can degenerate into aggressive squamous-cell carcinoma of the skin. © 2013 Springer-Verlag France.

As interrogativas de conteúdo nas variedades do português falado

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Aforização no discurso de autoajuda

In this paper, based on Maingueneau’s (2006, 2010) thoughts on aphorisation and on the differences between aphorising and textual enunciation, we analyze some detached utterances from the self-help discourse, by highlighting some of their meaning effects and their role in such discourse. The analysis shows that the aphorising detachments support the self-help discourse enunciator in the process of guiding the interlocutors. Such aphorizing detachments allow the enunciator to give order as if he or she were enunciating the truth, which attenuates the enunciator’s authoritative character, who is supposed to give order explicitly. Moreover, such utterances activate the play between “to say and not to say,” by simulating that the self-help discourse is based on an undeniable truth, which reinforces its persuasive power.

Tendências de normalização na tradução para o inglês da obra As Mulheres de Tijucopapa

The present essay aims at observing possible tendencies of normalization by the translator Irene Matthews in the translation to English from As mulheres de Tijucopapo, by Marilene Felinto. The methodology employed is that of corpus-based translation studies (proposed by BAKER, 1993, 1995, 1996, 2000; SCOTT’s study concerning normalization, 1998; and CAMARGO’s research studies, 2005, 2007), and that of corpus linguistics (BERBER SARDINHA’s studies, 2003, 2004). The investigation was carried out by means of a combination of semi-manual and computerized analyses using the computer software WordSmith Tools. Based on Scott (1998), we analyzed the translation of five words considered to be preferred by the author, as well as their co-text, in relation to three normalization features. The final results obtained in this study show that the translator Irene Matthews tends to use strategies that may be identified as features of normalization.

Avaliação das áreas de conflito de uso em APP na microbacia Ribeirão do Veado, Piratininga (SP) por meio de geotecnologias

Pós-graduação em Agronomia (Energia na Agricultura) - FCA

Intoxicação pela Metáfora segundo Gilles Deleuze e Félix Guattari: os desenhos do pequeno Richard (1941)

Starting with a critical review that make Deleuze and Guattari about the use of images in the writings and drawings reproduced in Narrative of a Child Analysis, by Melanie Klein, the authors reflect on the place of metaphor in the speech of this analyzed child about desiring life, intoxicated with Oedipian metaphors. They highlight the role of metaphor in the production of the alleged psychoanalytic intoxication.