Solving the conundrum of Job: a probable biblical description of chronic renal failure with neurological symptoms

A doença descrita no livro bíblico de Jó é controversa, e tem interessado a teólogos, psiquiatras e dermatologistas, há tempos. Neste trabalho os autores apontam para evidências do diagnóstico de insuficiência renal crônica com alterações neurológicas.

Análise intertextual do conto “A volta do marido pródigo”, de Guimarães Rosa, com a parábola O filho pródigo

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Adélia Prado e o diálogo com mulheres bíblicas

Pós-graduação em Letras - FCLAS

Digressões, transgressões, agressões: a Bíblia nos contos de Machado de Assis

Pós-graduação em Letras - IBILCE

Resistência da linha de cola em superfícies lixadas da madeira de eucalipto

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

A ironia na recriação paródica em novelas de Moacyr Scliar

Pós-graduação em Letras - FCLAS

As faces de Deus na obra de um ateu - José Saramago

Pós-graduação em Letras - FCLAS

Os animais não humanos no material didático do programa São Paulo Faz Escola

The relationship between humans and non-human animals dates back to the Prehistoric Era, when groups of humans migrated from the nomadic and extractive stage to sedentariness, starting to develop agriculture and animal husbandry. Ancient Greek philosophy, notably the Aristotelian school of philosophy, posited that nature has not done anything for nothing, and all things have a purpose: plants were created for the sake of animals, and these for the good of men, while the Bible preaches the view that the world was created for the good of men and other species were subordinated to their wants and needs. During the Renaissance, centuries XIV to XVI, anthropocentrism was established as the main philosophical concept. However, in relation to the treatment of animals, Renaissance did not differ substantially from medieval scholasticism, considering animals like machines, devoid of pain and immortal soul. In this context, scientific knowledge about plants, non-human animals and nature in general, is built on anthropocentric values, thus influencing the construction of school education in the disciplines of Science and Biology. Nowadays, at São Paulo state schools, specifically in the Ensino Fundamental II (6th to 9th grade), the program of the discipline Ciências da Natureza e suas Tecnologias is set by the Currículo Oficial do Estado de São Paulo, via the São Paulo Faz Escola Program, implemented by the Secretaria Estadual de Educação in 2010. This documentary research used the methodology of Content Analysis and aimed to analyze the presentation of non-human animals in Caderno do Professor and Caderno do Aluno, from 6th to 9th grades of the discipline Ciências da Natureza e suas Tecnologias. The analysis of the courseware revealed that its contents were influenced by the anthropocentric view, in both implicitly and explicitly ways, conveying anthropomorphic, utilitarian, stereotyped and derogatory statements towards...

The influence of the region between residues 220 and 344 and beyond in Phrixotrix railroad worm luciferases green and red bioluminescence

To find the regions having a major influence on the bioluminescence spectra of railroad worm luciferases, we constructed new chimeric luciferases switching the fragments from residues 1-219 and from 220-545 between Phrixotrix viviani (PxvGR; λmax = 548 nm) green light-emitting luciferase and Phrixothrix hirtus (PxhRE; λmax = 623 nm) red light-emitting luciferases. The emission spectrum (λmax = 571 nm) and KM for luciferin in the chimera PxRE220GR (1-219, PxhRE; 220-545, PxvGR) suggested that the region above residue 220 of PxvGR had a major effect on the active site. However, switching the sequence between the residues 226-344 from PxvGR luciferase into PxhRE (PxREGRRE) luciferase resulted in red light emission (λmax = 603 nm), indicating that the region 220-344 by itself does not determine the emission spectrum. Furthermore, the sequence before residue 220 of the green-emitting luciferase is incompatible for light emission with the sequence above residue 220 of PxhRE. These results suggest that the fragments before and after residue 220, which correspond to distinct subdomains, may fold differently in the green- and red-emitting luciferases, affecting the active site conformation.