Cortisol in saliva and plasma of cattle after ACTH administration and milking

Interest in the measurement of salivary cortisol has increased recently because saliva can be easily collected before and after an imposed stress. This study evaluated the relationship between plasma and salivary concentrations of cortisol following ACTH administration in calves ( experiment 1) and machine milking of adult cows ( experiment 2). A catheter was inserted into the jugular vein of all animals 72 h before the beginning of experiments. Blood and saliva samples were collected before and after ACTH administration (0.6 IU/kg BW) in calves or before and after machine milking of cows. Using a cotton swab, each saliva sample was taken immediately following the blood sample. In general, cortisol profiles were similar in plasma and saliva and correlated in both experiments; however, plasma concentrations were significantly higher than salivary concentrations. In addition, the differences between cortisol concentrations measured in saliva and plasma within each experiment varied substantially between animals and samples. Furthermore, in experiment 2, nearly 10% of salivary samples were below limits of detection. The sharp peaks in cortisol after ACTH administration in both the plasma and saliva were reflected adrenal stimulation. In addition, increases in cortisol in response to milking in both the plasma and saliva suggest that salivary sampling is a reliable option when studying cortisol responses to normal physiological events.

Plasma concentrations and behavioral, antinociceptive, and physiologic effects of methadone after intravenous and oral transmucosal administration in cats

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

O Banco Mundial e modelos de gestão educativa para a América Latina

Este artigo empreende a análise do discurso dos capítulos cinco e sete do documento do Banco Mundial: Para além do consenso de Washington: a importância das instituições, identificando e questionando a proposição de modelos teóricos para as reformas da administração pública e educacional na América Latina, com fundamento em autores preocupados em examinar o conceito de modelo teórico. A intenção é discutir as categorias envolvidas, suas ambigüidades e seu caráter inovador/conservador e definir se as propostas contidas no texto referido são nacional e regionalmente adequadas, se detêm o poder de transformar a realidade ou constituem apenas algo mais sobre a mesma coisa ou, pior, traduzem o resgate/elogio de modelos remodelados, inspirados na teoria empresarial, que alimentam a crítica dos acadêmicos regionais há décadas.

Acute and sustained effects of early administration of inhaled nitric oxide to children with acute respiratory distress syndrome

OBJECTIVE: To determine the acute and sustained effects of early inhaled nitric oxide on some oxygenation indexes and ventilator settings and to compare inhaled nitric oxide administration and conventional therapy on mortality rate, length of stay in intensive care, and duration of mechanical ventilation in children with acute respiratory distress syndrome. DESIGN: Observational study. SETTING: Pediatric intensive care unit at a university-affiliated hospital. PATIENTS: Children with acute respiratory distress syndrome, aged between 1 month and 12 yrs. INTERVENTIONS: Two groups were studied: an inhaled nitric oxide group (iNOG, n = 18) composed of patients prospectively enrolled from November 2000 to November 2002, and a conventional therapy group (CTG, n = 21) consisting of historical control patients admitted from August 1998 to August 2000. MEASUREMENTS AND MAIN RESULTS: Therapy with inhaled nitric oxide was introduced as early as 1.5 hrs after acute respiratory distress syndrome diagnosis with acute improvements in Pao(2)/Fio(2) ratio (83.7%) and oxygenation index (46.7%). Study groups were of similar ages, gender, primary diagnoses, pediatric risk of mortality score, and mean airway pressure. Pao(2)/Fio(2) ratio was lower (CTG, 116.9 +/- 34.5; iNOG, 62.5 +/- 12.8, p <.0001) and oxygenation index higher (CTG, 15.2 [range, 7.2-32.2]; iNOG, 24.3 [range, 16.3-70.4], p <.0001) in the iNOG. Prolonged treatment was associated with improved oxygenation, so that Fio(2) and peak inspiratory pressure could be quickly and significantly reduced. Mortality rate for inhaled nitric oxide-patients was lower (CTG, ten of 21, 47.6%; iNOG, three of 18, 16.6%, p <.001). There was no difference in intensive care stay (CTG, 10 days [range, 2-49]; iNOG, 12 [range, 6-26], p >.05) or duration of mechanical ventilation (TCG, 9 days [range, 2-47]; iNOG, 10 [range, 4-25], p >.05). CONCLUSIONS: Early treatment with inhaled nitric oxide causes acute and sustained improvement in oxygenation, with earlier reduction of ventilator settings, which might contribute to reduce the mortality rate in children with acute respiratory distress syndrome. Length of stay in intensive care and duration of mechanical ventilation are not changed. Prospective trials of inhaled nitric oxide early in the setting of acute lung injury in children are needed.

Proposta de uma abordagem metodológica para analisar como os fatores posicionais influenciam as prioridades competitivas

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Respostas zootécnicas, fisiológicas e comportamentais de ovelhas Santa Inês submetidas a diferentes fatores de estresse do início da lactação até o desmame

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Desafios e possibilidades na formação e no desenvolvimento profissional de administradores da UNIR

Pós-graduação em Educação Escolar - FCLAR

CONTRIBUTIONS OF OPERATIONS MANAGEMENT TO THE COMPETITIVENESS OF THE BRAZILIAN ELECTRONICS SECTOR

The objective of this paper is to identify and analyze various aspects of the internal and external operations management of Brazil's electronics sector and to consider the opportunities for and the threats to increasing the competitiveness of its participation in the global supply chain. To address this shortage in the literature, a survey of Brazilian Electric and Electronic Industry Association (ABINEE) companies was conducted. The collected data were complemented with secondary data to establish an overall view of the electronics sector in Brazil. The results suggest that electronics product assembly companies have the opportunity to invest more in information technology to expand process integration, plan and develop products, integrate customers, and maintain rather than expand their supply chain practices. The alignment between internal and external operations management becomes important in this context. The originality of this paper lies in its clarification of operations management in an economically important sector and the insight it provides to academics, practitioners and policy makers involved in the domestic and international electronics sector.

Concentrations of metronidazole in human plasma and saliva after tablet or gel administration

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Memória organizacional, memória corporativa e memória institucional: discussões conceituais e terminológicas

The proposal of present paper is to present a conceptual and terminological discussion relative to the terms: organizational memory, corporate memory and institutional memory that is a subject still little studied and explored in the academic area. The study is theoretical focus and the research kind is bibliographical. As research sources were utilized: books, digital libraries of theses and dissertations in the scope of the country and CAPES Journals Portal. This study is in course and is part of doctorate research "Organizational memory and the knowledge bases constitution". As the partial results, observes that the question about "memory" is studied by different areas of knowledge: Psychology, Neurosciences, History and others; the concepts about organizational memory and corporate memory are studied by Administration and Information Systems areas; the concept of institutional memory is more studied by Business Communication area focusing the company history. Beyond that, observes the use of another term, social memory, utilized by Information Science and History areas.

Jogos de empresas e gestão financeira: algumas evidências

This article aims to discuss the use of business games for educational purposes taking into account evidence about the difficulty in managing financial resources. The use of business games is justified because the young generation tha are coming to the education system have grown up using business games, allowing a more motivating learning environment and stimulating investment and on how the concept to provide learning. Instead of pushing content well defined and wel-formatted for the student, promotes the use of games promote at the same time, a chalenge whose solution entails learning effort. Thus, the use of games affect educators, students and aducational institutions, requiring them new attitudes and patterns of thought about schooling. The elaboration of this article was based on experiences gained with the development and use of games for educational purposes, specifically the game "Mercado Virtual". Several articles have been published on research with indergraduates and postgraduate courses in business administration and engineering field. They have shown that the evaluation of the player, based on their decisions during the game, to detect specific aspects of learning. This exploratory research is based on data obteained in various experiments with the game Mercado Virtual.

Gestão para eficiência energética: levantamento e análise da produção científica divulgada em alguns periódicos das áreas de engenharia de produção e administração (2001-2011)

This research leads to a meta-analysis of scientific production in energy efficiency in industrial sectors, recorded in ten (10) leading journals in Administration and Engineering Production in Brazil, between 2001 and 2011. To this end, this scholarship was examined based on the following parameters: a) the total contribution and journal articles, b) methods used in studies, and c) the theoretical gaps to exploit. The diagnosis is that one infers: academic work in energy efficiency industries accounted for only twenty-nine (29) published articles, and only eight (8) have energy efficiency as a central theme of the work. Although the results still showed a rising trend in the number of publications since the last five (5) years analyzed showed 65.5% of all published files relating to energy efficiency. It contributes, therefore, the systematization of the academic production in the area of energy efficiency and business subsidies are provided for this field of research in Brazil.

A Complexidade da Administração/Gestão Escolar, Limites e Possibilidades

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)