158 resultados para neurofunctional reorganization


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Presents a developing laboratory within History of Culture, subject taught in the Library and Archive Studies at UNESP (Marilia). The project is based upon the foundations of research line Information and Technology: students from the second under graduation year participate in the improving of 27 entries in Portuguese language Wikipedia. The aim is to capacitate for scientific reading and writing in digital media, habilitate for the information identification and recuperation and for the interpretation and understanding of formal and contents aspects and its reorganization. It includes activities of search, selection, remix and republishing of texts, images, audio and videos in the convergence of diverse hypertext information sources, supported by tutors with strategic abilities in digital environments. In this sense it was adhered to the international Wikipedia Foundation University Campus Ambassadors project. It’s also aimed to induce sharing and collaboration behaviors with the purpose of creating necessary habits for the informational empowerment in Brazil. As methodology is to optimize the work of individuals already trained in wiki culture and to create in within the subject information sharing programs with a more specialized bias, giving greater credibility to the digital environment. The environment syntaxes helps in the learning of the complementary skills of reading and writing and offers itself as an open repository from which information can be reused. It is, thus, an empowerment strategy in the search of autonomy and self reliance considering intersemiotic knowledge in the edition, visualization and understanding of information in the social web. A second step of a verifying research on the environment’s credibility after the consolidation and dissemination of the entries improvement work is proposed.

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Coming as a result from a comprehensive research based on Lima’s studies (2008), this article is intended for investigating the process of reorganization of the Pedagogy course offered by a state public university since 2006, when the new National Curricular Guides were instituted. The subject matter brings up as one of its purposes to identify the main difficulties and the possible answers given in order to cause the changes to happen, taking in consideration both the external and internal interests of the institution. To further these aims, actual instruments were applied to the research: documents related to the Pedagogy course that were kept in the Council of the university and interviews with the members who took part in the process of readjustment. Because it is a public university, at first there was a mistaken presumption of the primacy of an administration founded upon democratic principles, in which the divergent opinions do not turn out to be taken as mere pretexts, but as an opportunity of dialogue and to establish collective projects. However, the results of the analysis shook that basic assumption and proved the opposite: the process was led to a rational/bureaucratic pattern of administration, the goals of which intended to adjust the institution to the external precepts and to establish the consensus — understood here as an absolute lack of conflicts. Nevertheless, it was chosen to conciliate the Pedagogy course to the national guides, without causing any harm to the departmental interests. These are reasons that justify satisfactorily the fact of this article being supposed to raise and quicken new and revitalized debate whenever there is an engagement of those who are most concerned for the duty of student teachers’ instruction, but mainly that of being expected to participate in the effective discussion/decision — making process of creating ends which to strive and work for.

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The German philosopher G.W.F. Hegel (1770-1831) had as one of his thesis in the doctorate the affirmation that philosophy can only be properly taken as a system. He intends with that to point out the identity between thinking and being. This is, for Hegel, the task of philosophy, i. e., to bring together all that was set apart. This position can be recognized in all his works and it is tried here to exemplify it in The Philosophy of Right and in special in the section dedicated to the abstract right. This one is the first moment of the text in question that begins with the statement of the dignity of the person confirmed in the property. The following moments make evident that the formal ones are also results. It becomes clear in this way that the all the moments create together an ongoing organization, disorganization and reorganization. This process reveals the relation as a constitutive element of thinking and being exemplified in the abstract right. Each moment overcomes the preceding one and comes out as a much more complex one. In the case of the abstract right what appears is the realization of a free subject in all that he does as the making of himself.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Oocyte maturation is a complex process involving nuclear and cytoplasmic maturation. The nuclear maturation is a chromosomal segregation and the cytoplasmic maturation involves the reorganization of the cytoplasmic organelles, mRNA transcription and storage of proteins to be used during fertilization and early embryo development. The mechanism of oocyte maturation in vivo and in vitro still are not totally understood. However it is generally accepted that the second messenger cyclic adenosine monophosphate (cAMP) plays a critical role in the maintenance of meiotic blockage of mammalian oocytes. A relative increase in the level of cAMP within the oocyte is essential for maintaining meiosis block, while a decrease in cAMP oocyte concentration allows the resumption of meiosis. The oocyte cAMP concentration is regulated by a balance of two types of enzymes: adenylate cyclase (AC) and phosphodiesterases (PDEs), which are responsible for the synthesis and degradation of cAMP, respectively. After being synthesized by AC in cumulus cells, cAMP are transferred to the oocyte through gap junctions. Thus, specific subtypes PDEs are able to inhibit or attenuate the spontaneous meiotic maturation of oocytes with PDE4 primarily involved in the metabolism of cAMP in granulosa cells and PDE3 in the oocyte. Although the immature oocytes can resume meiosis in vitro, after being removed from antral follicles, cytoplasmic maturation seems to occur asynchronously with nuclear maturation. Therefore, knowledge of the oocyte maturation process is fundamental for the development of methodologies to increase the success of in vitro embryo production and to develop treatments for various forms of infertility. This review will present current knowledge about the maintenance of the oocyte in prophase arrest, and the resumption of meiosis during oocyte maturation, focusing mainly on the changes that take place in the oocyte.

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The disorded and unnplaned occupation is not recent in out territory but it concerns to a historical territorial invasion that roots the time of our country discovery. However, they have started to cause issues nowadays, as in the case of urban conurbations. Somehow these unorganized urban, industrial and agricultural occupations did not have any sort of information or indication of the appropriate situation at that time. Because of that there has been researches by several groups to induce the users of the several renewable and non renewable resources to explore them according to their natural potential capacity.The Ceramic Pole of Santa Gertrudes, the national largest producer of ceramic tile, faces this problem of disorder occupation. Among other themes, the reorganization of the physical environment, proposed by several groups of researchers and scholars of this subject, is gaining attention now.The method of Geoenvironmental Zoning results in a way of prevention from this issue. Crossing information of the physical environment and generating maps whose areas and subdivisions have similar characteristics, it is possible to manage studies and handle these areas according to their potentiality.

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The Atlantic Rainforest biome has been going through fragmentation processes caused by agriculture and urbanization in green areas. Structural studies associated with the silvigenetic approach allow the understanding of what the past has caused in the present structure and predict future conditions of disturbed fragments. The objective of this study was to compare the composition and diversity of arboreous natural regeneration of steady-state and reorganization ecounits in two Seasonal Semideciduous Forest fragments. The hypothesis was that specific composition varies in these two different ecounits due to differential adaptation of species in canopy gaps and closed canopy. The survey was made in three areas with different perturbation backgrounds of 0,5 ha each. 60 permanent plots of 4m² each (2m x 2m) were stablished along the studied fragments following the proportion of ecounits presented in a previous mapping. Each plot was divided in 4 sub-plots of 1m² and arboreous individuals between 0,20m and 1,30m height were sampled and posteriorly separated in two height classes: I) individuals between 0,20m and 0,50m height (2m² sampling) and II) individuals between 0,51m and 1,30m height (4m² sampling). It was sampled 338 individuals from 53 families and 23 species. The Shannon index was 3,26 (Area A), 2,27 (Area B) and 2,42 (Area C) whereas Areas B and C values are considered low in our state Semidecidous Forests. Steady-state ecounits presented the highest values for abundance and species richness. Chi-square test pointed out species’ selection for determined ecounits in the studied community. Rarefaction method analysis showed diversity increase in steady-state ecounits and a stablishment in species richness curves for reorganization ecounits

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In this paper, I focus on one type of grammatical change consisting of creating periphrastic junctures from nominal sources used in relative clause contexts. This is a periphrase production mechanism that has been increasing the unstable paradigm of junctures and helping delineate Portuguese language grammar. One construction resulting from this mechanism is (na) hora que, in relation to which I propose to investigate form, meaning and history. The central aim is to show the emergence of (na) hora que, a grammaticalization instance in course, in which it is possible to catch stages of the its gradual constitution process, concerning both the syntagmatic reorganization of items with consequent morphological losses, and the constitution of meanings, with the origin of polysemies, pointing to a directionality grounded on the increase of the cognitive complexity

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Chromatoid body (CB) is a typical cytoplasmic organelle of germ cells, and it seems to be involved in RNA/protein accumulation for later germ-cell differentiation. Despite most of the events in mammals spermatogenesis had been widely described in the past decades and the increase in the studies related to the CB molecular composition and physiology, the origins and functions of this important structure of male germ cells are still unclear. The aims of this study were to describe the nucleolar cycle and also to find some relationship between the nucleolar organization and the CB assembling during the spermatogenesis in mammals. Cytochemical and cytogenetics analysis showed nucleolar fragmentation in post-pachytene spermatocytes and nucleolar reorganization in post-meiotic spermatids. Significant difference in the number and in the size of nucleoli between spermatogonia and round spermatids, as well as differences in the nucleolar position within the nucleus were also observed. Ultrastructural analysis showed the CB assembling in the cytoplasm of primary spermatocytes and the nucleolar fragmentation occurring at the same time. In conclusion our results suggest that the CB may play important roles during the spermatogenesis process in mammals and that its origin may be related to the nucleolar cycle during the meiotic cell cycle.

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Cancer is a multistep process that begins with the transformation of normal epithelial cells and continues with tumor growth, stromal invasion and metastasis. The remodeling of the peritumoral environment is decisive for the onset of tumor invasiveness. This event is dependent on epithelial–stromal interactions, degradation of extracellular matrix components and reorganization of fibrillar components. Our research group has studied in a new proposed rodent model the participation of cellular and molecular components in the prostate microenvironment that contributes to cancer progression. Our group adopted the gerbil Meriones unguiculatus as an alternative experimental model for prostate cancer study. This model has presented significant responses to hormonal treatments and to development of spontaneous and induced neoplasias. The data obtained indicate reorganization of type I collagen fibers and reticular fibers, synthesis of new components such as tenascin and proteoglycans, degradation of basement membrane components and elastic fibers and increased expression of metalloproteinases. Fibroblasts that border the region, apparently participate in the stromal reaction. The roles of each of these events, as well as some signaling molecules, participants of neoplastic progression and factors that promote genetic reprogramming during epithelial–stromal transition are also discussed.

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Pós-graduação em Educação Matemática - IGCE

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This academic report presents results of the research developed between 2012 and 2015, and it had as main goal the development of new mapping possibilities of the central areas of the cities of Marília/SP, São Carlos/SP and São José do Rio Preto/SP. We developed this research using mostly the database from Cadastro Nacional de Endereços Para Fins Estatísticos (CNEFE), and after processing the information, it was added the typology established in the Cadastro Nacional de Atividades Econômicas (CNAE). This database, after the final treatment process, provided us information that made possible the production of thematic maps which are used to study central areas, allowing the analysis of spatial logics of companies, the identification of concentration and dispersion of economic activities, arrangement of specialized axis, expansion of the central area, reorganization of the city, among other process and phenomena