Efeitos da estimulação elétrica neuromuscular nas circuitarias medulares inibitórias de sujeitos crônicos após acidente vascular cerebral

Pós-graduação em Fisioterapia - FCT

Comparação da perfusão vascular folicular, luteal, uterina e perfil hormonal plasmático entre éguas jovens e idosas suplementadas ou não com L-Arginina

Pós-graduação em Biotecnologia Animal - FMVZ

Controle autonômico do coração e fração de ejeção na fase crônica do acidente vascular encefálico

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Negligência unilateral pós-acidente vascular encefálico: atuação da Terapia Ocupacional

Unilateral Neglect Syndrome is one of the consequences of cerebral vascular accident (CVA) generally following right parietal lobe lesion, leading to the impairment of perceptive visual, spatial and attention functions. The patient affected does not realize the environmental stimuli on the contralesional hemibody. Occupational therapy plays an important role in caring for this patient, seeking the recovery of perception, attention and social engagement. This study aimed to describe and evaluate the results of occupational therapy intervention and treatment in a single Unilateral Neglect Syndrome post CVA patient. Data were obtained from a survey of the patient’s medical records and interviews of his therapist and caretaker. The analysis of the patient’s medical records and his therapist’s report showed that the patient responded satisfactorily to treatment, presenting a decrease of the left unilateral neglect at the end of the study period. The favorable outcome of the patient outlined the relevance of evaluating the effects of Occupational Therapy interventions for clinical unilateral neglect syndrome.

Efeitos da Fisioterapia Respiratória na Mecânica Respiratória de Pacientes com Acidente Vascular Encefálico Ventilados Mecanicamente

Patients who went through a Stroke may require mechanical ventilation (MV) in the acute phase of the disease and, on MV, they may show alterations in the respiratory mechanic. Physiotherapy techniques are applied in patients on MV to improve their respiratory mechanic. Thus, the purpose of this study was to evaluate the effects of the Respiratory Physiotherapy into the dynamic compliance (Cdyn), static compliance (Cst) and airway resistance (Rwa) in Stroke patients on MV. In order to do that, patients with Stroke diagnostic on MV were evaluated, before and after the use of Physiotherapy techniques (manual rib-cage compression, thoracic decompression, zero end expiratory pressure and suctioning). Cdyn, Cst and Rwa were the researched variables. Statistical Analysis was made using Paired T-Test with statistical significance with p-values no greater than 5%. Eleven patients were part of the study, with an average of 64,6±12,5 years old. Cdyn increased after physiotherapy from 29,3±16,1 ml/cmH2O to 33,8±16,7 ml/cmH2O (p=0,03). Cst also increased from 44,4±20,7 ml/cmH2O to 54,0±26,6 ml/cmH2O (p=0,024). No significant difference was detected for Rwa between the before and after moments (Before – 8,0±3,2 cmH2O/l/s, After – 7,3±2,25 cmH2O/l/s; p=0,45). It was possible to conclude that both dynamic and static compliance increased after physiotherapy, but the airway resistance did not increase in patients with stroke on mechanical ventilation.

Physical exercise and vascular endothelial growth factor (VEGF) in elderly: A systematic review

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Cardiovascular alterations at different stages of hypertension development during ethanol consumption: Time-course of vascular and autonomic changes

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Gestational protein restriction delays prostate morphogenesis in male rats

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

MORPHOGENESIS AND PRODUCTION OF TANZANIA, MOMBACA AND MULATO GRASSES UNDER NITROGEN FERTILIZATION

A field trial was conducted designed in a completely randomized block in a 4 x 3 factorial arrangement to evaluate the application of nitrogen doses (N) (0, 40, 80 and 160 kg/ha) on the morphogenical characteristics and dry matter partition of three forage grasses (Panicum maximum cvs. Mombasa and Tanzania and Brachiaria sp. Hybrid Mulato). The leaf appearance (LAR, leaf/day) and stretching (LER; mm/day) rates, the number of green leaves per tiller (NLT) and the average weight of tillers (MTW; g) presented s positive linear response to the N dose while the phyllochron (Phil; day/leaves) showed a negative linear response. The highest LER, IAL and final leaf length (FLL; cm) occurred in the Mombaca and Tanzania grasses, while the highest LAR occurred in the Mulato grass. There was a negative quadratic effect of the N dose on the stem elongation rate (SER; mm/day) and LF. The Mombaca and Tanzania grasses presented the highest SER; however, in just two forages. The production of total dry matter (TDM; kg/ha), leaves (LDM; kg/ha) and stems (SDM; kg/ha) increased linearly and quadratically with the N dose, respectively, for the Mombaca and Tanzania grasses. There was a high positive correlation among DM, LDM and SDM and the Mombaca grass MTW. The dry matter production and morphogenic characteristics were influenced by the nitrogen fertilization as a result of the substantial increase in the flow of tissues stimulated by fertilization, proving the importance of N for forage biomass accumulation.

Efeitos da exposição à sílica sobre a responsividade vascular e de vias aéreas de ratos

Silicosis, a common type of pneumoconiosis, is an occupational lung disease caused by inhalation of silica dust often with mining activity and thus reaches the miners. The fine and ultrafine silica particles deposited in the alveolar epithelium may lead to the development of progressive massive fibrosis. An increased reactive oxygen species (ROS) production has been proposed to explain the mechanism for induction of pulmonary fibrosis in silicosis. In this situation, alveolar macrophages are activated to phagocytes silica particles deposited in the alveoli. The activated macrophages secrete large amounts of ROS that in turn induce synthesis of fibrotic factors. In addition, the activity of antioxidant enzymes is impaired, which results in increased lipid peroxidation, as well as generating a local inflammatory process. Diffuse pulmonary fibrosis progresses with interstitial collagen deposition. Interstitial collagen overlies small pulmonary arteries and arterioles and thus it is associated with pulmonary hypertension in pulmonary fibrotic diseases. In addition, cytokines and silica particles passing through the respiratory membrane can reach the bloodstream. In this context, the increase in the generation of ROS in the circulation may lead to a reduction in the bioavailability of nitric oxide, an important endothelium-derived relaxing factor. A deficiency in the nitric oxide bioavailability can result in vascular endothelial dysfunction. Moreover, pro-inflammatory cytokines could contribute to the impairment of endothelial function. In the airways, pro-inflammatory cytokines can reduce the smooth muscle responsiveness to β- adrenergic agonists as isoproterenol. Thus, the aim of this study was to evaluate the effect of silica dust instillation in the function of the pulmonary artery, aorta and trachea of rats with acute silicosis. For this purpose, male Wistar rats were anesthetized... (Complete abstract click electronic access below)