Salivary and serum proteomics in head and neck carcinomas before and after surgery and radiotherapy

Several body fluids have been evaluated as new sources for cancer biomarker discovery. In this context, salivary and serum proteomics seem promising diagnostic and predictive tools for head and neck diseases. In the present study, we performed a proteomic analysis of saliva and serum from patients presenting head and neck squamous cell carcinoma (HNSCC) and compared the results before and after therapy. In saliva of cancer patients, we observed an altered protein profile, including over-expression of PLUNC and zinc-alpha-2-glycoprotein. Both proteins may contribute to control tumor growth and, therefore, represent targets for new analysis. We also detected serotransferrin and a modified transthyretin form with altered levels in serum from patients. Comparing preoperative and postreatment samples, the results showed that the protein profile after treatment reverted to a pattern closer to those observed for controls. These results add information on the role of secreted proteins in the cancer process and emphasize the potential of saliva and serum analysis for diagnosis and monitoring of HNSCC.

Criação de um banco de itens para avaliar o conhecimento do câncer de cabeça e pescoço

Pós-graduação em Odontologia Preventiva e Social - FOA

Design e gênero: diretrizes metodológicas para validação do uso da linguagem visual na roupa infantil

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Sperm characteristics of Steindachneridion parahybae (Steindachner, 1877) throughout 112h of storage at four temperatures

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

The influence of handrim design on the contact forces on hands'surface: a preliminary study

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

An esthetics rehabilitation with computer-aided design/ computer-aided manufacturing technology

This paper describes a case of a rehabilitation involving Computer Aided Design/Computer Aided Manufacturing (CAD-CAM) system in implant supported and dental supported prostheses using zirconia as framework. The CAD-CAM technology has developed considerably over last few years, becoming a reality in dental practice. Among the widely used systems are the systems based on zirconia which demonstrate important physical and mechanical properties of high strength, adequate fracture toughness, biocompatibility and esthetics, and are indicated for unitary prosthetic restorations and posterior and anterior framework. All the modeling was performed by using CAD-CAM system and prostheses were cemented using resin cement best suited for each situation. The rehabilitation of the maxillary arch using zirconia framework demonstrated satisfactory esthetic and functional results after a 12-month control and revealed no biological and technical complications. This article shows the important of use technology CAD/CAM in the manufacture of dental prosthesis and implant-supported.

Análise de parâmetros neuromusculares e cinemáticos dos chutes Bandal Chagui e Dolhô Chagui do Taekwondo

Pós-graduação em Desenvolvimento Humano e Tecnologias - IBRC

Procedimentos metodológicos em design gráfico voltados a jornais diários impressos: estudos e relatos de experiência

This paper summarizes a research that has been developed from the concern about a company’s strategic planning, once regarding the product development process and its methodological guidelines. Our goal was to check if there is an ideal methodology, peculiar to the graphic design, which could be applied to a printed newspaper condition. And then, we could deduce, according to the design practices in newspapers, its relevance. We did not intend to create a specific graphic design methodology for daily newspapers, nor the analysis of methods, but we wanted to emphasize that the familiarization with acknowledged methods in the field of visual communication, during the process of professional formation, might ease good choices in the work practice on design. The understanding of the gradual introduction of graphic design on printed daily newspapers brings about, thus, not only their visual improvement, but also allows that this kind of journalism (which depends on a graphic interface in order to make their product come true) reconsider the newspaper as a whole.

Processo de avaliação de uma disciplina de Design de Interiores

This study aims to present the strategies and assumptions used to evaluate a class entitled Design Furniture seeking their improvement and adapting the expectations of the profession of Interior Design Technologist. Initially the study focused on the contexts of Design Teaching and Higher Education in Brazil, with the purpose of adequacy of theory with practice. The method of continuous evaluation was used over two semesters with two classes. This study presents and discusses the data of one of the groups. This evaluation method helped in adequacy of teaching regarding the methodology, content and expectations of students and teacher. As a result, furniture were produced based on the type of evaluation chosen by the student, showing academic progress.

Produção de repolho em função da idade das mudas

The seedling transplanting ages is a factor of great importance because it can affect the quality and yield of plants if the volume of the cell is not compatible with the phenology of seedlings at time of transplantation. The experiment was conducted at São Manuel Experimental farm, Faculdade de Ciências Agronômicas da UNESP, from March to August, 2009. The objective of this study was to evaluate the effect of seedling age on cabbage production, hybrid Kenzan. The seedlings were grown in polystyrene trays containing 128 cells. Seedings were done every four days and contained the following treatments: 37, 41, 45, 49 and 53 days after sowing (DAS). The experimental design was randomized blocks, with five replications. On transplantation’s day (11/05/2009), the number of leaves, fresh and dry weight and height, were evaluated to the characterization of seedlings. It was observed that the seedling age had no influence on traits at harvest: number of leaves inside and outside of “head”, fresh weight of shoot and “head”, dry mass of shoot and “head” and length of “heart”.

Inovação em design: planejamento e estratégias para um parque tecnológico na região de Bauru - SP

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

A relação entre a álgebra acadêmica e a álgebra escolar em um curso de licenciatura em matemática: concepções de alunos e professores

Pós-graduação em Educação - FCT