Efeito do ácido tranexâmico associado à cola de fibrina sobre o reparo ósseo: estudo histológico em ratos

The bone repair process is controlled by complex molecular mechanisms that involve systemic and local factors. Fibrin glue is derived from human plasma and mimics the final pathway of coagulation network. Tranexamic acid inhibits fibrinolysis and prevents or decreases the formation of degradation products of fibrin and fibrinogen. The purpose of this study was to evaluate histologically in rats the effect of tranexamic acid associated with the fibrin glue on bone healing. The experiment used 60 (n = 5) male rats in: GI: Control, GII: fibrin glue, GIII tranexamic acid and GIV /fibrin glue/tranexamic acid. Bone defect (2.5mm diameter) was created in right tibia. The animals were euthanized at 7,14 and 30 days postoperatively, and the pieces were processed with hematoxylin and eosin. The results showed at 7 days post-operative surgical cavity filled with dense connective tissue rich in fibroblasts, permeated by delicate neoformed bone trabeculae in percentage of 70-80% for GI, GII and GIII and GIV to 94.8%. At 14 days post-operative newly formed bone was found between 75-85% for GI, GII and GIII and percentage above 95% for GIV. At 30 days postoperative GI and GIV showed 95-100% of mature bone tissue; GII and GIII in percentage close to 80-90%. Based on the results and methodology is concluded that fibrin / tranexamic acid glue association has positive action on bone repair.

A pesquisa em televisão digital no Brasil: apontamento sobre o levantamento bibliográfico realizado de 1995-2008 sobre o assunto

In Brazil, the discussion about thereplacement of analog television signals to digitaland its impact on society, in media companies andgovernment began in the 90s. Embryonic steps towardsdigitalisation of the television signal ground were thegovernment of Fernando Collor de Mello (1990-1992),with advances during the government of FernandoHenrique Cardoso (1994-2001) and in the governmentof Luiz Inacio Lula da Silva (2002). The academy startsthe discussion in 1996. This article aims to bring to lightthe results obtained from the survey Digital television:a historical perspective , which received the supportof CNPq for funding of two scholarships for scientifi cinitiation between August 2008 and July 2009. Theproject sought to identify what has been published onthe subject in the fi eld of Social Sciences and from threemacrodescritores (information management, publicpolicy and value chain), providing the li ing of a virtualcollection Zotero bibliographic innovative platform.The mapping serves to show the growing interest anddevelopment of research in the country during theperiod - when the number jumped to three works inthe fi rst seven years (1995-2001) to 198 in the last sevenyears (2002-2008). The research sought to identify themajor authors and works related to digital televisionand published in the country. The survey took intoaccount books, articles published in books, journals,Annals of Compós and Intercom, and dissertations andtheses. Data and refl ections on the survey are containedin this communication.

Dimensões da qualidade em serviços: um estudo no setor de B2C brasileiro

With the focus on quality of services, this work uses a methodology based on questionnaires for evaluating companies and consumers, with the objective of studying the dimensions of quality within the segment of Brazilian e-commerce. The research conducted a study to identify the situation of companies regarding the dimensions of quality and, among costumers, a survey was done to determine their requirements with regard to these dimensions and to identify those dimensions considered as winning factors when making the orders. The results demonstrate that customers consider reliability to be the most important order winner, followed by safety and communications. The study of these enterprises demonstrates that their quality of service is good, however there is a need for improvements in the business processes related to the dimensions of service quality.

Supply chain strategies in the context of an ecommerce chain (E-Chain)

This paper purpose to explore the relationships between supply chain strategies and product performance in retail e-commerce. In this case, we concern that in current, in order to bear up under competition, organizations have to manage their supply chains so that they meet the needs of their final customers. With this concept in mind, the research presented in this study focuses on establishing the right strategy for supply chains according to their product segment. Thus, after a Literature Review, the paper explain a methodology based in different authors studies. Finally the article focuses on a pratical case in e-commerce retail that describes its application in this field. The research shows that it is possible to use a methodology for classifying supply chains using chain strategies and product features. The use of the right strategy for supply chains will improve the competitive advantage of businesses. One limitation is that the methodology study focuses on only two e-commerce segment; future studies may go further in refining the proposed framework for other segments. The aim of this research is to offer businesses a model for evaluating supply chains, allowing them to improve the performance of their products and services by using the right strategy for supply chains. The classification proposal of this paper presents an original model for classification of supply chains based on different studies on the theme.

Uma nova forma de narrar a história: a renovação do romance histórico em Luiz Ruffato

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Encefalopatia hepática: relatório da 1º reunião monotemática da Sociedade Brasileira de Hepatologia

Hepatic encephalopathy (HE) is a functional disorder of the central nervous system (CNS) associated with liver failure, either end-stage chronic liver disease or fulminant hepatic failure. Its pathogenesis remains complex and poorly understood. In view of recent advances in the management of HE, the Brazilian Society of Hepatology endorsed a monothematic meeting regarding HE in order to gather experts in the field to discuss related data and to draw evidence-based recommendations concerning: management of HE and intracranial hypertension in FHF, treatment of episodic HE in cirrhosis, controversies in the management of EH including difficult to treat cases and diagnostic and treatment challenges for minimal HE. The purpose of this review is to summarize the lectures and recommendations made by the panel of experts of the Brazilian Society of Hepatology.

Avaliação de acessos de germoplasma do gênero Paspalum na Amazônia Oriental

This study was carried out at Campo Experimental do Cerrado in Embrapa Amapá, Brazil, aiming to select, based on the agronomic characteristics of productivity, dry matter and nutritional quality of the forage, the accesses of species from the genus Paspalum that possess potentiality of use as forage plants. During the years 2000, 2001 and 2002, 21 accesses of grasses were evaluated, including 18 of Paspalum and three control species: Brachiaria decumbens, Andropogon gayanus cv. Baetí and Brachiaria brizantha cv. Marandú. The experimental design was complete randomized block with three replications. The variables studied were: production of dry matter, neutral detergent fiber on the dry matter, in vitro digestibility of dry matter and crude protein content in the dry matter. All the accesses showed marked reduction in productivity and quality of produced forage, when the climatic conditions became unfavorable, showing that Paspalum as the other tropical grasses have high seasonal production. Based on the variables studied, the selected accesses were P. guenoarum (BRA-014851), P. atratum (BRA-9661) and Paspalum sp. (BRA- 009407).

Eletronarcose no abate de frangos de corte: Iderlipes Luiz Carvalho Bossolani. -

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Aniceto dos Reis Gonçalves Viana (1840 - 1914): o linguista em seu tempo

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)