Avaliação da medida de independência funcional - escala MIF - e qualidade de serviço - escala SERVQUAL - em cirurgia cardíaca

Pós-graduação em Bases Gerais da Cirurgia - FMB

Implementação de um sistema para geração e avaliação de movimentos em pacientes hemiplégicos

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Neurotoxicidade perinatal por cádmio em ratos wistar e interação com clorpirifós

Pós-graduação em Medicina Veterinária - FMVZ

Desenvolvimento de um protótipo para medida da pressão plantar durante a marcha, com e sem o uso de um dispositivo de auxílio

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Análise das variáveis eletromiográficas e da pressão plantar na marcha em aclive, declive e plano

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Colapso induzido pelo exercício em um Labrador Retriever

The exercise-induced collapse (EIC) is a hereditary disease characterized by muscle weakness, impaired locomotion and collapse after intense exercise. This autossomic recessive disorder affects mainly Labrador Retriever presenting the mutation c.767G>T in the dynamin 1 (DNM1) gene. The objective of this study is to report the first case of exercise-induced collapse in Labrador Retriever in Brazil. The molecular test detected the specific genetic mutation and confirmed the clinical diagnosis in a Labrador Retriever with clinical history of weakness and collapse after exercise. It is important to include this disease as part of the differential diagnosis of neuromuscular diseases in Labrador Retriever and use the molecular test to guide matings.

Revisão sistemática do efeito do envelhecimento no andar livre e adaptativo

Aging seems to impair the walking. However, it is not clear the effects of aging on walking. The aim of this study was to determine changes in kinematic, kinetic and electromyographic parameters of the free and adaptive gait, in preferred velocity, caused by aging. The initial search strategy was performed to identify all articles that examined the free and adaptive gait. The electronic databases analyzed were: MEDLINE, PubMed, EMBASE, CINAHL, Sports Discus, DARE, PsychInfo, ERIC, AusportMed, AMI, Cochrane and PEDro. Twenty-three articles were reviewed in full. Elderly are slower, with shorter step length and longer double support duration than young adults during free and adaptive gait. Even, they showed higher muscular demands, with redistribution of joint power and torque and decreased force in the propulsion and absorption phases. It was concluded that elderly present altered kinematic, kinetic and electromyographic parameters of free and adaptive gait compared to young adults.

Desenvolvimento de uma plataforma aberta de robô móvel para propósitos gerais

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Effect of watergym in knee osteoarthritis

Objective: Evaluate the effectiveness of watergym to alleviate knee osteoarthritis (OA) symptoms and improve locomotor function. Methods: Forty-two volunteers, 38 women and four men with OA, practicing watergym, divided into the following groups: beginners, intermediate, advanced, and advanced level with other physical activities in addition to watergym were included in the study. Individuals were assessed at times zero, 8 and 12 weeks, with classes lasting 45 minutes, twice a week. Function was assessed by the Aggregate Locomotor Function (ALF) score, and pain and other symptoms by the visual analogical scale (VAS) and by the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) questionnaire. Statistical analysis was carried out by the variance analysis for repeated measurements, followed by Tukey's method for comparison of time point means whenever required. Results: None of the tests showed a significant improvement of pain or locomotion. Conclusion: Watergym was not effective in improving symptoms and did not affect the locomotor capacity of individuals with knee OA.

Swimming performance in semiaquatic and terrestrial Oryzomyine rodents

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

One step forward: contrasting the effects of Toe clipping and PIT tagging on frog survival and recapture probability

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Permethrin chronic exposure alters motor coordination in rats: Effect of calcium supplementation and amlodipine

Recently was observed that pyrethroids decrease motor coordination and that calcium channels can be important targets for this effect. To contribute with this observation, this work studied the motor coordination and exploration (using hole-board apparatus), and locomotion (using open-field apparatus) of rats exposed to following treatments: permethrin (PM), PM plus calcium gluconate (CG) and PM plus amlodipine (AML). The results obtained show that CG or AML alone not changed the motor coordination while PM decreases it. CG kept the effect of permethrin; AML, however, decreased the values of permethrin to the control. Locomotor activity and exploration, which could confound results of motor coordination, were not modified by treatments. The concentration of PM in brain tissue was increased by the CG and AML. The neurosomatic index (weight brain/body weight) was increased by the PM and PM + CG. In conclusion, the combined results here obtained indicates that the calcium ion and the channels in which it is involved can be important targets for the toxic effect of pyrethroid insecticide permethrin on motor nerve activity of rats. (c) 2014 Elsevier B.V. All rights reserved.

Reproductive toxicology and clastogenic evaluation in mice of a phytotherapeutic formulation obtained from Cinchona calisaya Weddel (Rubiaceae) used in Brazilian folk medicine as female fertility stimulant

Ethnopharmacological relevance: In Brazil, a phytotherapeutic preparation produced from a standardized tincture of Cinchona calisaya Weddel such that each mL of product contains 400 mu g of quinine, known in Portuguese as Agua Inglesa (R) (English water), is indicated by the manufacturer as a tonic, appetite stimulant, and digestive. However, this preparation has long been used in folk medicine as a female fertility stimulant. Despite its widespread use in folk medicine to stimulate female fertility, no study has been undertaken to assess the potential teratogenic and genotoxic effects of this phytotherapeutic preparation. The aim of the present study was to investigate possible toxic reproductive effects in mice caused by exposure to Agua Inglesa (R), either before mating or during the pre- and post-embryo implantation periods. The genotoxic potential was evaluated using the micronucleus assay.Material, Methods, and Results: Virgin female mice, with at least one estrous cycle evidenced by vaginal cytology, were divided into five groups of 15 individuals each (Group I - control, Group II - treated with ethanol solution at 16%, Groups III, IV and V treated with phytotherapeutic preparation at 1.5 mL/kg/day, 3.0 mL/kg/day and 4.5 mL/kg/day, respectively). After the first 28 days of treatment, females were caged individually with adult fertile males. Pregnant females continued to receive treatment for seven days (preimplantation period). Body weight was recorded weekly during treatment. Signs of toxicity (weight loss, food intake, piloerection, apathy, prostration, diarrhea, seizures, behavioral changes, and locomotion) were also observed. The females were sacrificed on the 15th day of pregnancy, uterine horns were evaluated for implantation, and the placental index was recorded. In the micronucleus test, 2000 polychromatic erythrocytes (PCE) per animal, obtained from bone marrow, were scored. Results The results showed that exposure of the females during the pre- and post-implantation periods did not significantly alter the reproductive capacity (p < 0.05); however, in higher dose (three times human dose)reduction of fetal weight was observed. There was no difference between the control and phytotherapeutic preparation (p > 0.05) in terms of the average number of micronucleated polychromatic erythrocytes.Conclusions: Although folk medicine suggests that the Agua Inglesa (R) preparation is useful as a female fertility stimulant, no such effect was confirmed in mice. (C) 2014 Elsevier Ireland Ltd. All rights reserved.

Alterations in the profile of blood neutrophil membrane receptors caused by in vivo adrenocorticotrophic hormone actions

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Parasitoid-host interaction: sensory structures involved in the parasitism behavior of Bracon vulgaris (Hymenoptera: Braconidae)

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)