Minimplante e botão lingual como ancoragem para retração inicial de caninos superiores: estudo prospectivo

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Políticas públicas e desenvolvimento rural na região de Presidente Prudente: Programa Nacional de Fortalecimento da Agricultura Familiar e Programa Estadual de Microbacias Hidrográficas

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Colágeno acelular e mucosa oral na substituição parcial da uretra: estudo comparativo em coelhos

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Distribuição ecológica e dinâmica populacional do camarão barriga branca Nematopalaemon schmitti (Holthuis, 1950) (Caridea, Palaemonidae) na região de Macaé-RJ, Brasil

Pós-graduação em Ciências Biológicas (Zoologia) - IBB

Textured macro- and mesoporous alumina samples designed in the presence of different surfactant types

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Abordagens da biomecânica ortodôntica utilizando mini-implantes

As an innovative transitory anchorage device, the mini-implants deserve to be described with details regarding its use and action during orthodontic treatment. Therefore, this paper intents to present some biomechanic criteria adopted to for a better use of mini-implants as anchorage in anterior retraction (space closure), molar distalization, mesial movement of the molars, intrusion of molars and as support to provisional implant.

A contribuição de modelos utilizando uma abordagem modelo - código

In a world that is increasingly working with software, the need arises for effective approaches that encourage software reuse. The reuse practice must be aligned to a set of practices, procedures and methodologies that create a stable and high quality product. These questions produce new styles and approaches in the software engineering. In this way, this thesis aims to address concepts related to development and model-driven architecture. The model-driven approach provides significant aspects of the automated development, which helps it with produced models built in the specification phase. The definition of terms such as model, architecture and platform makes the focus becomes clearer, because for MDA and MDD is important to split between technical and business issues. Important processes are covered, so you can highlight the artifacts that are built into each stage of model-driven development. The stages of development: CSM, PIM, PSM and ISM, detailing the purpose of each phase in oriented models, making the end of each stage are gradually produced artifacts that may be specialized. The models are handled by different prospects for modeling, abstracting the concepts and building a set of details that portrays a specific scenario. This retraction can be a graphical or textual representation, however, in most cases is chosen a language modeling, for example, UML. In order to provide a practical view, this dissertation shows some tools that improve the construction of models and the code generate that assists in the development, keeping the documentation systemic. Finally, the paper presents a case study that refers to the theoretical aspects discussed throughout the dissertation, therefore it is expected that the architecture and the model-driven development may be able to explain important features to consider in software engineering

Parâmetros oftálmicos em espécimes de Cuniculus paca criadas em cativeiro

Pós-graduação em Cirurgia Veterinária - FCAV

Loss of nuclear poly(A)-binding protein 1 (PABPN1) causes defects in myogenesis and mRNA biogenesis

The nuclear poly(A)-binding protein 1 (PABPN1) is a ubiquitously expressed protein that plays a critical role in polyadenylation. Short expansions of the polyalanine tract in the N-terminus of PABPN1 lead to oculopharyngeal muscular dystrophy (OPMD), which is an adult onset disease characterized by eyelid drooping, difficulty in swallowing and weakness in the proximal limb muscles. Although significant data from in vitro biochemical assays define the function of PABPN1 in control of poly(A) tail length, little is known about the role of PABPN1 in mammalian cells. To assess the function of PABPN1 in mammalian cells and specifically in cells affected in OPMD, we examined the effects of PABPN1 depletion using siRNA in primary mouse myoblasts from extraocular, pharyngeal and limb muscles. PABPN1 knockdown significantly decreased cell proliferation and myoblast differentiation during myogenesis in vitro. At the molecular level, PABPN1 depletion in myoblasts led to a shortening of mRNA poly(A) tails, demonstrating the cellular function of PABPN1 in polyadenylation control in a mammalian cell. In addition, PABPN1 depletion caused nuclear accumulation of poly(A) RNA, revealing that PABPN1 is required for proper poly(A) RNA export from the nucleus. Together, these experiments demonstrate that PABPN1 plays an essential role in myoblast proliferation and differentiation, suggesting that it is required for muscle regeneration and maintenance in vivo.

External apical root resorption in retracted incisors

AIM: To evaluate the occurrence of external apical root resorption (EARR) in the incisors after anterior retraction in corrective orthodontic treatment with first premolar extractions and whether it was related with the type of root apex movement and its inclination. METHOD: The maxillary and mandibular incisors of 22 patients (12 to 25 years of age; 9 males and 13 females) were treated with fixed appliances and premolar extraction. EARR was defined as the difference in root length before and after incisal retraction on periapical radiographs. Distortion of radiographic images and changes due to incisal tipping were controlled for. Pre- and post-incisal retraction lateral cephalometric radiographs established the relationship between EARR and the tipping of the incisors, along with the vertical, horizontal, and total movement of the root apex. RESULTS: There was significant EARR (1.51 to 2.37 mm) during incisor retraction, but this was not related to the movement or the tipping of the root apex of almost all teeth. It was observed that after the retraction stage, EARR occurred in all evaluated incisors, but it was more significant (P < .05) in the mandibular right lateral incisor. CONCLUSION: The EARR that did occur was unrelated to movement or tipping of the root apex, except for the vertical root apex movement of the mandibular left central incisor and the inclination of the maxillary right lateral incisor.

Necessidade de ancoragem do grupo A e o controle biomecanico da mola T pré-ativada por curvatura para o fechamento de espacos

Contemporary orthodontics has sought, beyond the esthetic, occlusal and functional goals, treatments even faster and with less visits to the orthodontist — especially in patients that require dental extractions in which the generated space becomes a nuisance. The segmented arch technic (SAT), by the use of a "T" loop spring, has provided such results within these requirements. Therefore, this study aimed to appraise and demonstrate the confection, activation and biomechanical control of "T" loop spring, in the group with high anchorage necessity (group A), for retraction of anterior teeth; as well as to present a case report, with high anterior retraction necessity, treated with "T" loop spring.

A questão da diferença na sociedade contemporânea: reflexões a partir de zygmunt bauman

The objetive of this article is discuss the question of difference and alterity presents in analyzes of contemporary society conducted by the polish sociologist Zygmunt Bauman. The author observed that human relations are guided by a logic of cost-benefit connected with values of present in the discardability of consumer society. At the same time, it has built ways of eliminating difference through the construction of a politics of expulsion of those considered strangers. For the author, the cities are the materialization of the ambivalence of live with the other people in contemporary times, being the locus of experience approach and retraction to the other expressed by fear of the difference. The result of this process is the impoverishment relational, the feeling of loneliness and an ethical-political crisis seen that could be seen from the primacy of the private/intimate rather than the public dimention/action.

Uso de plasma rico em plaquetas em úlceras de córnea em cães

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Hemangiossarcoma corneal em cão

Hemangiosarcoma is a malignant neoplasm and its corneal presentation is uncommon in the dog. The present work reports a case of primary corneal hemangiosarcoma on a mongrel female dog, 20kg, nine years old with a 2 month history of a mass with progressive growth in the right eye. The ophthalmic examination of the right eye showed blepharospasm, moderated conjunctival hyperemia and the presence of a reddish irregular nodule on the dorsal region of the cornea, occupying approximately 60% of the cornea. The ocular ultrasound revealed that the neoplasm affected only the cornea and the cytological examination diagnosed a malignant mesenchymal neoplasm. The patient was submitted to keratectomy followed by a third eyelid flap. The excised material was sent for histopathological analysis that diagnosed hemangiosarcoma. Fifteen days after surgery the third eyelid flap was removed and the ophthalmic examination revealed recurrence of the tumor, with the mass occupying the entire cornea and part of the bulbar conjunctiva. The patient was submitted to enucleation. No alterations were observed on the abdominal ultrasound and thoracic radiography, showing the primary characteristics of the disease. Two years after surgery the patient is clinically healthy, without any signs of recurrence or metastasis. Despite the surgical excision of the tumor with free margins, in cases of hemangiosarcoma with aggressive behavior, the enucleation should be considered as a viable option for a successfull therapeutic protocol and better prognosis of the patient.

Chin augmentation with conchal cartilage

Profile enhancement most frequently involves mentoplasty. For this purpose, the author performs conchal grafts to the chin. A total of 28 women aged 15 to 76 years (mean age, 38.11 ± 15.11 years) requested mentoplasty by itself or combined with rhinoplasty, rhytidoplasty, or submental lipoplasty. The conchal cartilage was harvested subperichondrally through a posterior 3-cm incision. The specimen measured 3 x 1 cm, which was sufficient to project the chin 2 to 3 mm. For 4 to 5 mm of projection, both cartilages were used. The graft was positioned under the periosteum and held with two 5-0 nylon sutures. In these cases, the conchal cartilage graft was a suitable option for chin augmentations up to 5 mm.