The roles of environmental conditions and spatial factors in controlling stream macroalgal communities

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Differences in the hydroxylation pattern of flavonoids alter their chemoprotective effect against direct- and indirect-acting mutagens

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Ácido protocatecúico e seus ésteres alquílicos: propriedades antioxidantes e seus efeitos no metabolismo oxidativo de leucócitos

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Segurança na América Latina: cenários e perspectivas

In the post Cold War period, in the security field, has increased the mechanisms of cooperation and coordination among the Latin American states, in the context of so called confidence-building measures. These arrangements presented as important and efficient tools of political-strategic articulation and assist in the maintenance of peace in the region. The paper presents some considerations about the current scenario in terms of security and defense in Latin America. Initially, presents concepts of security and defense and perceptions of threats by the states. Then, discusses the mechanisms of cooperation and coordination in security have been established on the American continent in the periods of the Cold War and post Cold War. Finally, presents considerations regarding the scenario and the prospects of security issues in the region.

Effect of Eu substitution on the crystallographic and magnetic properties of the BiMn2O5 oxide obtained by urea combustion

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Mechanisms of phase formation along the synthesis of Mn-Zn ferrites by the polymeric precursor method

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Healing Process of Autogenous Bone Graft in Spontaneously Hypertensive Rats Treated With Losartan: An Immunohistochemical and Histomorphometric Study

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Corrective effects of acerola (Malpighia emarginata DC.) juice intake on biochemical and genotoxical parameters in mice fed on a high-fat diet

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

The role of proestrus on fertility and postovulatory uterine function in the cow

Modern protocols to synchronize ovulations for timed artificial insemination and timed embryo transfer that include manipulations in the proestrus period (i.e., between luteolysis and estrus) affect fertility in cattle. Specifically, stimulating pre-ovulatory follicle growth and exposure to estrogens after CL regression increase the proportion of cows pregnant and decrease late embryo mortality. Such effects may be due to both preovulatory actions of estrogens and post-ovulatory actions of progesterone, as concentrations of the later hormone may be changed in response to manipulations conducted during proestrus. In the first portion of this paper we describe strategies used recently to manipulate the proestrus period in protocols for synchronization of ovulation, and to present evidence of their effects on fertility. Manipulations of timing and prominence of sex steroids during the proestrus and early diestrus that affect fertility may act on targets such as the endometrium. This tissue expresses receptors for both estrogens and progesterone and these hormones change endometrial function to support conceptus growth and pregnancy maintenance. However, specific cellular and molecular mechanisms through which fertility is affected via manipulations of the proestrus are poorly understood. In the second portion of this paper we describe a well-defined animal model to study changes in endometrial function induced by manipulations conducted during the proestrus. Such manipulations induced endometrial changes on sex steroid receptors expression, cell proliferation, oxidative metabolism and eicosanoid synthesis in the uterus, but not on glucose transport to uterine lumen. In summary, evidence is accumulating to support a positive role of increasing duration and estrogen availability during the proestrus on fertility to synchronization protocols. Such positive effects may be through changes in endometrial function to stimulate conceptus growth and survival.

Influência das substâncias húmicas aquáticas na genotoxicidade dos metais em tilápias do Nilo (Oreochromis niloticus)

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Prostate hyperplasia caused by long-term obesity is characterized by high deposition of extracellular matrix and increased content of MMP-9 and VEGF

Recent studies have shown a positive association of cancer and obesity, but the morphological and molecular mechanisms involved in this relationship are still unknown. This study analysed the impact of long-term obesity on rat prostate, focusing on stromal changes. Male adult Wistar rats were treated with high-fat diet to induce obesity, while the control group received a balanced diet. After 30 weeks of feeding, the ventral prostate was analysed by immunohistochemistry for cell proliferation, smooth muscle α-actin, vimentin, chondroitin sulphate and metalloproteinases (MMP-2 and 9). The content of androgen receptor (AR), oestrogen receptors (ERs) and vascular endothelial growth factor (VEGF) was measured by Western blotting, and activity of catalase and Glutathione-S-Transferase (GST) were quantified by enzymatic assay. Long-term obesity decreased testosterone plasma levels by 70% and resulted in stromal prostate hyperplasia, as evidenced by increased collagen fibres. Such stromal hyperplasia was associated with increased number of blood vessels and raised VEGF content, and increased expression of chondroitin sulphate, vimentin, α-actin and MMP-9. In spite of the high cell density in prostate, the proliferative activity was lower in the prostates of obese rats, indicating that hyperplasia was established during the early phases in this obesity model. AR levels increased significantly, whereas the ERα decreased in this group. Moreover, the levels of catalase and GST were changed considerably. These findings indicate that long-term obesity, besides disturbing the antioxidant control, causes intense stromal remodelling and release of factors that create an environment that can promote proliferative disorders in the gland, culminating with diffuse hyperplasia.

Perfil de fatores de virulência das Escherichia coli isoladas do útero de vacas holandesas após o parto e sua relação com a microbiota uterina

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Blog para o basquetebol: uma ferramenta no processo ensino-aprendizagem-treinamento dos sistemas táticos

Pós-graduação em Desenvolvimento Humano e Tecnologias - IBRC

O grupo como produtor de singularidades: o processo subjetivo como forjador de singularidades frente às pessoas que vivem com as DSTs

The personal experience respective is a description of an psychosocial intervention effectuated in the year of 2007 in an institution not government, in the city of Taubaté, with a group of women infected with the virus HIV. We will present in the short form our work, which happened through a therapeutic group, that had as device, the production of new process of subjectivizing with these women in the conduction of them condition of life after the infection with the virus HIV. To determine our actions use the theoretical assumptions of genealogy, of psychology and the theory of institutional operating group with emphasis on aspects of group discussion. During approximately twelve meetings with the denser group work topics such as social violence (inequality of rights, prejudice and stigma), treatment of the condition of serum positive when marked by ambivalence to treatment and the use of defense mechanisms: denial, projection and omnipotence, the weak and intense physical and mental suffering resulting from this process.We end our exhibition while presenting the discursive constructions and, consequently, the multiforms singular potentialities of the group that appeared with our psychosocial interventions.

Desamparo psíquico na contemporaneidade

This article has as a purpose to make a theoretical reflection on the experience of helplessness in the recent days. It starts from the Freud’s concept of helplessness, and compares it with analyses and reflections from contemporary authors on models of subjectivation which have risen at the present time. In the first experiences of life helplessness comes out as a result of an incompleteness of the organism, its need to perform exchanges with the world, and the extreme dependency on help from others. On the one hand, the contemporary culture highlights the individualism, which indicates good possibilities for granting desires. On the other hand, it makes bonds and relationships ephemeral and fragile. At the absence of a solid, safe and stable continent for affective and emotional experiences a feeling of helplessness appears. It activates primary defense mechanisms, contributing to the intensification of regressive forms of subjectivation and the decline of the symbolic sphere.