Keratocyst of the buccal mucosa: case report and immunohistochemical comparative study with sporadic intraosseous keratocystic odontogenic tumor

Objectives: Describe a new case of keratocyst of the buccal mucosa and compare its immunohistochemical features with 13 sporadic intraosseous keratocystic odontogenic tumors (KOT). Case Report and Study Design: A male complaining about an enlargement on the left buccal mucosa was referred to the Stomatology Clinic. Clinical examination revealed a solitary nodule posterior to the parotid papilla. An excisional biopsy was performed following clinical diagnosis of epidermoid cyst. Microscopically, the lesion was characterized by a lining of five cell layers, with columnar basal cells and a corrugated parakeratinized surface. Immunohistochemical reactions for PTCH-1, Smo, Shh, mTOR, bcl-2, Ck17, and Ck19 were performed. PTCH-1 was not expressed in the keratocyst of the buccal mucosa, but was observed in suprabasal layers of eight (61.5%) cases of sporadic intraosseous KOT. Shh, mTOR, bcl-2, Ck17, and Ck19 expression was observed in all the cases investigated. Conclusions: The morphology and immunoprofile of this lesion are similar to sporadic intraosseous KOT. © 2013 Elsevier Inc. All rights reserved.

Investigation of the state of virus carrier of newcastle disease in budgerigars (melopsittacus undulatus)

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Light microscope observations on the epididymis of paca (Agouti paca)

The features of paca epididymis, based on its appearance in light microscope, is described in this paper. The cellular population of the epithelial lining comprises principal cells, basal cells, apical cells, narrows cells, and hallo cells. The epididymis is divided in five distinct and continuous regions, Zone I, or initial segment, and zone II, are both localized into the head. Zone III comprises the distal head and all the body. Zones IV and V are restricted to the tail, in the proximal and distal cauda epididymis respectively. Each zone can be readily distinguished on the basis of morphological characteristics. The height of epididymal epithelium is greater in zone I. There is a progressive increase in the diameter of the tubular lumen through the different areas, with the maximum in the zone V. The presence of a high epithelium, and the virtual absence of sperm in zone I suggest fast transit of spermatozoa in this region. Zone V comprises the distal tail, has smaller epithelial lining, greater luminal diameter, shorter stereocilia than the other zones, and contains spermatozoa packed inside the lumen, that characterizes this zone as a place of sperm storage. The findings are compared with other reports in rodents and other domestic animals, to contribute to the understanding of epididymal morphophysiology. © 2013 Firenze University Press.

Detection of cytokeratins in ghost cells of calcifying cystic odontogenic tumor indicates an altered keratinization and hair follicle differentiation for their development

Calcifying cystic odontogenic tumors (CCOTs) are benign cystic lesions of odontogenic origin characterized by an ameloblastoma-like epithelium and the presence of a group of cells named ghost cells. The pattern of cytokeratin (Ck) expression on these lesions remains unclear and needs to be clarified. To this end, the expression of Ck6, Ck13, Ck14, Ck18, and Ck19 in the epithelium lining of 7 cases of CCOTs was evaluated by immunohistochemistry. For this, the epithelium lining was divided into 3 distinct regions: basal layer, suprabasal layer, and the compartment composed of ghost cells. In this study, 6 cases (85.7%) were classified as type 1 and 1 (14.3%) as type 4. All cases were negative for Ck13 and Ck18, despite the epithelial layer, as well as in the ghost cells. Ck6 was only positive in the ghost cells. Positivity for Ck14 and Ck19 was found in the basal and suprabasal layers, including the ghost cells. The results showing positivity for Ck14 and Ck19 in all of the analyzed cases reinforce CCOT as being of odontogenic origin, and the restricted expression of Ck6 in the ghost cells may be indicative that these cells suffer an altered differentiation into hair follicles in CCOTs. © 2013 Elsevier Inc. All rights reserved.

Análise histopatológica e ultraestrutural do esôfago distal de ratos com lesão cáustica submetidos à aplicação tópica de mitomicina C

Pós-graduação em Bases Gerais da Cirurgia - FMB

Estudo morfológico e histoquímico do tubo digestivo de eleuteroembriões e larvas de Leporinus obtusidens (Valenciennes, 1836)

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Substituição precoce do alimento vivo pelo alimento inerte na larvicultura de acará bandeira (Pterophyllum scalare)

Pós-graduação em Aquicultura - FCAV

Avaliação quantitativa de micronúcleos na citologia esfoliativa da mucosa bucal de pacientes dependentes químicos

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Avaliação da atividade oxidativa do Acidithiobacillus ferrooxidans sobre uma mistura composta de diferentes proporções dos sulfetos minerais pirita e calcopirita

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Indução de Acidithiobacillus ferrooxidans e seleção de linhagens mutantes para utilização na biohidrometalurgia

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Biossolubilização da calcopirita na presença dos íons cloreto e ácidos orgânicos

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Estudos físico-químicos e de lixiviação de calcopirita (CuFeS.IND.2) por Acidithiobacillus ferrooxidans

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Biolixiviação de minério de cobre da mina de Sossego, PA - Companhia Vale do Rio Doce

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Oxidação da calcopirita (CuFe S'IND.2') por Acidithiobacillus ferooxidans em presença de cisteína e de Acidithiobacillus thiooxidans

Pós-graduação em Biotecnologia - IQ

Eficiência de três cimentos de ionômero de vidro como dissipadores de cargas em bases de restaurações de resina composta: análise por meio da extensometria elétrica

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)