192 resultados para Resíduos de medicamentos


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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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Polymorphism can cause quality deviations during the production of medicines and can influence their effectiveness. Therefore, an understanding of this phenomenon and its implications opens a wide field of possibilities to be explored in the pharmaceutical field, including the emergence of new paradigms and tools for the quality assurance of medicines. This paper presents an introduction to basic aspects of the polymorphism phenomenon and its implications for the production and control of medicines, with emphasis on drug polymorphs.

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Several factors have contributed to the increase the world production of urban solid waste, resulting in difficulties to the correct management and the final environmentally appropriate disposal, in addition to causing serious socio-economic, environmental, and public health troubles. The soil and groundwater contamination by leachate in waste disposal sites is almost always present, leveraging the emergence and/or adaptation of methodologies for environmental assessment of these areas. The geophysical methods, especially the electrical resistivity method, are fast, reliable and low-cost alternative for this purpose. This paper reports the methodology adopted for the temporal monitoring of the plume of contamination of controlled landfill in the municipality of Rio Claro (SP). Electrical resistivity data were obtained in 1999 and 2008, by the resistivity method, using the techniques of vertical electrical sounding and electrical profile. In both years, similar tests were carried out in the same locations within the disposal area. The results indicated that the plume of contamination has resistivity values less than or equal to 50 ohm.m and moves guided by 2 flows: the main, to the southeast, and the secondary, to the west. Relatively to the first series of tests in 1999, the plume of contamination was higher and deeper in 2008, contrary to what was expected for a landfill deactivated for at least 10 years.

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This article presents an analysis of the quality of advertisements for over-the-counter (OTC) drugs addressed to the medical profession, based on the new Anvisa resolution RDC 96 (17/12/2008). For this analysis, 16 volumes of the Brazilian Journal of Medicine (RBM) were collected, from August 2009 to December 2010. To investigate the quality of the adverts, we prepared a questionnaire divided into three parts. In total, 160 advertisements were found, of which 27 were related to drugs exempt from prescription, from 9 laboratories. It was observed that none of the advertisements complied fully with the new rules, as required by legislation (RDC 96/08), with violations ranging from identification of the advert to prohibitions of human figures and subjective messages. Therefore, it was concluded that there is a need to implement more effective monitoring, so as to improve the quality of the adverts, so they can be used as a reliable source of information and update by prescribers.

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Taking into account the current context about environmental concern, the main purposes of this research were to develop and apply indicators in order to evaluate waste residues management in airports. As a result, 17 indicators related to generation, storage, transportation, collection, and solid waste disposal were created. These were applied in Viracopos International Airport, in Campinas, São Paulo State, Brazil. The results obtained in the study had a 2.9 performance, in a scale from one to five, characterized as regular. Posteriorly, the main weaknesses in waste residues management were analyzed in such Airport, as well as good practices and solutions were identifed. The highlighted management strategies suggested were the adjustment of areas for waste storage, recycling, and residues composting.

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The disposal of solid waste can create environmental problems, in addition to the potential risk of instability even in planned geotechnical works, such as provisions in stacks or high ends of the landfill, because they represent mere adjustments in civil engineering works. The Leme city, SP, generates about 35 t/day of municipal waste, that are deposited in a landfill located in the Barro Preto neighborhood. This work conducted a geophysical survey, based on geotechnical instability evidence in area, for analysis of the conditioners that cause on the sides leachate resurgence landfill and its relationship to mass movements and ravines installation in cover soil, with consequent waste exposure. The results indicate horizons of low resistivity connected with resurgence points generated by the organic matter decomposition contained in the waste. Such horizons result in leachate concentration in some places, which, in turn, may lead to loss of cohesion of the materials constituting the residues mass. The results are areas with mass flow by rotational movements, which, together with the surface flow of rainwater, evolves into ravines and exposed residues, preferably at the resurgence point. The leachate flow on the surface affects areas beyond the limits at landfill with direct impact on local agriculture and risk to pedestrians using the highway bordered by the landfill beyond the soil and the local aquifer.

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A review and analysis of the literature on educative interventions (EI) for medicine users was carried out. For this purpose, databases were searched by employing descriptors related to pharmaceutical care, education and health, covering the period from 1997 to early 2011. A set of 21 articles related to EI with medicine users were selected, 18 (85.7%) of which referred to studies on basic health care. The EI most commonly reported in the articles were: talks, group discussions and educative material. The positive outcomes reported were: improvement in quality of life (better acceptance of the disease), economic advantages (reduction in number of medical consultations) and clinical improvement (risk reduction, prevention of complications).

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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Pós-graduação em Aquicultura - FCAV

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)