Chin augmentation with conchal cartilage

Profile enhancement most frequently involves mentoplasty. For this purpose, the author performs conchal grafts to the chin. A total of 28 women aged 15 to 76 years (mean age, 38.11 ± 15.11 years) requested mentoplasty by itself or combined with rhinoplasty, rhytidoplasty, or submental lipoplasty. The conchal cartilage was harvested subperichondrally through a posterior 3-cm incision. The specimen measured 3 x 1 cm, which was sufficient to project the chin 2 to 3 mm. For 4 to 5 mm of projection, both cartilages were used. The graft was positioned under the periosteum and held with two 5-0 nylon sutures. In these cases, the conchal cartilage graft was a suitable option for chin augmentations up to 5 mm.

Nanotechnology-based drug delivery systems for the treatment of Alzheimer's disease

Alzheimer's disease is a neurological disorder that results in cognitive and behavioral impairment. Conventional treatment strategies, such as acetylcholinesterase inhibitor drugs, often fail due to their poor solubility, lower bioavailability, and ineffective ability to cross the blood-brain barrier. Nanotechnological treatment methods, which involve the design, characterization, production, and application of nanoscale drug delivery systems, have been employed to optimize therapeutics. These nanotechnologies include polymeric nanoparticles, solid lipid nanoparticles, nanostructured lipid carriers, microemulsion, nanoemulsion, and liquid crystals. Each of these are promising tools for the delivery of therapeutic devices to the brain via various routes of administration, particularly the intranasal route. The objective of this study is to present a systematic review of nanotechnology-based drug delivery systems for the treatment of Alzheimer's disease.

Case report: Cornelia de Lange Syndrome (CDLS)

The Cornélia of Lange´s syndrome is a genetic anomaly, described and published by Cornelia Catharina of Lange in 1933, however, their aspects were described previously by Winfried Robert Clemens Brechmann in 1916, that’s why it is also known as Brachmann of Lange’s syndrome. The most frequent clinical characteristics include typical face dismorfia, variable degree of mental delay, anomalies of the hands and feet, multiple malformations, retardation of the pre and postnatal physical development and microcephaly variable intellectual compromising. Some facial characteristics are peculiar and they are mixed with the inherited lines of their own family, the united brows, the long lashes, the small nose, the round face, the fine lips and lightly inverted. As oral manifestations they present micrognathia, dental crowding, periodontal disease, delayed dental eruption, enamel hypoplasia, erosion of the enamel and dentine caused by stomach acids of the gastroesophageal reflux and atresia of the dental arches. The purpose of this paper is to present a clinical report of a boy bearer of this syndrome assisted at CAOE - FOA - UNESP, emphasizing the importance of multiprofessional team for the diagnosis and treatment of this syndrome.

Uma gota de suor e o universo da Educação Física: um olhar semiótico para as práticas corporais

This essay raises problems around the possible relationships of Semiotics, understood as science that investigates the life of signs, with Physical Education. It emphasizes the Semiotics or the General Logic of Signs elaborated by Charles S. Peirce (1839-1914), and presents its fundamentals, applications and implications for research in the field of Physical Education. It concludes that Semiotics allows launching new epistemic looks at the analysis and intervention in Physical Education, in order to: comprehend all its manifestations as expressive, meaningful and communicative; review the existing dichotomies in Physical Education; claim for the enhancement of looking at the subjects, their conducts and living motion situations as producers of language, and, therefore, of communication with the world.

Características do aço API X70 utilizado em tubos de transporte de petróleo e gás

Having in mind that petroleum's history presents a huge growth, the exploration and production areas have been receiving lots of investments, in order to attend the increasing demand for gas and petroleum. Looking through that scenario, new technologies have been evolving in favor of discovering new natural petroleum deposits and act with effectiveness in truly deep waters without giving up the worldwide best operational security practices. The use of rigid pipes in marine installations have been rising quickly and, thanks to this reality, the many storage and pipe launching forms became study objects and are getting improved. The analysis of steel API X70 characteristics, proving that they are suitable for use in pipes developed to transport gas and petroleum is the theme of this presentation. A tensile test was conducted to determine the base metal's mechanical properties, draining's tension, traction's resistance, elasticity's modulus and maximum tension. An aspect that is concerning too is the metallographic analysis, in order to determine the studied iron's microstructure. Results of analyzes showed that the steel has high resistance, with good capacity for deformation and well defined yield point, concluding suitable for the application in question

Estudo do efeito Bauschinger em tubos de aço API 5l x70 aplicados no transporte de petróleo e gás

Despite the growing concern in seeking more sustainable energy sources, oil demand is likely to grow in coming years. To keep up with this growth, the oil industry has increasingly invested in innovation and efficiency. Knowing that, new technologies have been developed to explore deeper waters, without giving up the best practices in worldwide operational safety. The use of rigid pipelines in deepwater offshore facilities is increasing quickly and because of this, the ways of storing and launching pipe have been studied and perfected. In this paper the Bauschinger effect on API 5L X70 steel was analyzed proving that there was a reduction in yield strength when an effort was applied in a previous direction, then an effort was then applied in the opposite direction. To observe this phenomenon, the tensile test was conducted to determine the mechanical properties of the base metal, such as yield stress, tensile strength, elasticity and maximum tensile, so then compare it with the results obtained in the Bauschinger Effect Test. The analysis results showed that the steel had high resistance, with good plastic deformation capacity without failing, well-defined yield point, showing itself appropriate for the operation of oil and gas pipes