Efeitos de drogas antiplaquet��rias na doen��a periodontal

The association between platelets, angiogenesis and progression or repair of periodontal disease has been little explored and, consequently, the results are inconclusive. The pathogenic bacteria present in the periodontal pocket release endotoxins that affect the endothelial integrity and are able to induce the production of chemical mediators derived from plasma proteins and blood clotting while altering platelet function. There is great interest in the modulation of platelet activity in vascular disorders, especially cardiovascular diseases. For this reason, antiplatelet drugs, that are commonly used in the prevention of thromboembolic diseases, such as myocardial infarction, ischemic stroke and peripheral arterial disease, have been used. Aspirin is the only non-steroidal antiinflammatory agent with antiplatelet activity. In the periodontium, instead of only reduces levels of inflammatory cytokines, also significantly affects bleeding on probing, suggesting a dose-dependent modulation of periodontitis. In contrast, clopidogrel and ticlopidine are thienopyridine drugs with no known antiinflammatory action, suggesting that this benefit is related to an antiinflammatory effect indirectly correlated to their antiplatelet activity already established. In the literature there is limited information about the effect of these drugs on periodontium and periodontal disease development. Antiplatelet drugs hypothetically can change both the pathogenesis of periodontitis and subsequent periodontal tissue repair by blocking the secretion of chemical mediators which in general are important in modulating inflammation and tissue repair.

Poder soberano e biopol��tica no combate ��s drogas no Brasil

In the last two or three decades has become common the debate on the harmful effects produced by trade and use of illicit substances in Brazil. The "drug problem" as it became known worldwide in official and media discourses, has become, if not the only, at least the most important determinant of a series of social ills that affect both the rich countries (classified as consumers), and the poor countries (the producers and exporters of these "evil substances"). This situation that today is extremely pernicious, may be better understood through some elements of the story of its constitution. In this sense, we draw a succinct history of drug prohibition worldwide and we use the Foucauldian concept of biopower and the concept of ���death policy��� designed by Andr�� Saldanha Costa to comment briefly on the "drug problem" in Brazil. In this initial approach, we can affirm the importance of these two concepts for the understanding of the ���depoliticized life" of drug traffickers as well as the governmental policies, both legal and health focused on this issue.

Juventude, drogas e biopol��tica

In this article, we tackle the issue of youth and drugs as something linked to biopower and biopolitics, both concepts developed by Michael Foucault. Youth and drugs are taken and analyzed in situations involving the management of crime linked to the risks and deviations from the law, abuse and dependence. The youth; irreverent, courageous, healthy, idealistic, and that wanted to change the world for the better as we have seen in the past, is now strongly related to violence, dangerous activities, moral and social risks, drug addiction, criminality, and others negative images. To deal with these young people, tolerance and small punishments of yore are not enough anymore. The young people emerge as a segment of the population subject to various actions and programs. The drugs now are seen as matters of security and public health. There is a shifting and repositioning in the discourse about the young - from minor, drugged, and criminal to lawbreaker, user and drug addict. The change is subtle, but represents a modulation in the devices of social control. Beyond the consent of the young to get rid of drugs, there is a search for the creation of a wide area of monitoring of their behavior through the activation of community protection networks. The belief that the young are more impressionable and vulnerable, and that action on the cause of the problem or risk reduction are the most efficient ways of management, taking responsibility away from personal and family sphere and transferring it to the State, contributes to the increasing control of young people nowadays.

O adolescente, tr��fico de drogas e fun����o paterna

The involvement of adolescents as workers in the trafficking of illicit drugs has increased in recent decades in Brazil, and perhaps the world, making them also victims and perpetrators of violent acts related to this activity. Given the above, we conducted research ��� that now present some results in this article ��� on such subjects. Basically, we pretend to understand if they had, throughout its history, references to the authority that contributed to its entry in that class. The teens were chosen social stratum of low income and working on trafficking. We conducted interviews / conversations with these individuals and analyzed according to the perspective of psychoanalysis extramural. We conclude that, for them, such activity is a possible route in our society, to gain social recognition and feeling of belonging to the adult world and the society of consumers.

Express��o proteica das enzimas metabolizadoras de drogas no carcinoma de c��lulas escamosas de boca em pacientes jovens

P��s-gradua����o em Biopatologia Bucal - ICT

An��lise de teses internalistas subjacentes �� modelagem computacional da mente em uma perspectiva situada, incoporada e auto organizada

Funda����o de Amparo �� Pesquisa do Estado de S��o Paulo (FAPESP)

Inclus��o escolar de crian��as com necessidades educacionais especiais: levantamento bibliogr��fico de teses, disserta����es e trabalhos de conclus��o de curso no acervo online da UNESP

Essa pesquisa teve como objetivo discutir e analisar a quest��o da inclus��o escolar tendo em vista explorar a produ����o acad��mica a respeito da tem��tica a fim de comparar as tend��ncias metodol��gicas de estudo e relatar as evolu����es hist��ricas ao longo desde a d��cada de 90. Para isso, o presente trabalho est�� estruturado em tr��s cap��tulos: o primeiro uma breve retrospectiva hist��rica cultural entre deficientes, escola e a sociedade; o segundo sobre a forma����o continuada e inicial do professor inclusivo e o terceiro descreve os resultados do levantamento bibliogr��fico realizado na base de dados online da UNESP, considerando trabalhos de conclus��o de curso, disserta����es e teses defendidas entre 1990 e 2013. Os dados coletados foram analisados qualitativamente, com alguns resultados quantitativos. Ap��s a coleta de dados, os trabalhos foram analisados com base nos seguintes crit��rios: objetivos, local da pesquisa, tipo de delineamento, instituto onde o trabalho foi apresentado, principais resultados, instrumentos e tipos de participantes (quando configurar uma pesquisa emp��rica). Pretendeu-se verificar, se existe uma tend��ncia na metodologia de trabalhos cient��ficos em rela����o a esse tema, de pesquisas mais de cunho bibliogr��fico ou emp��rico, dado a sua complexidade

Tr��fico de drogas il��citas nos Andes: a dimens��o regional da coopera����o e da seguran��a

P��s-gradua����o em Rela����es Internacionais (UNESP - UNICAMP - PUC-SP) - FFC

Curso de capacita����o para l��deres, volunt��rios, profissionais e gestores de comunidades terap��uticas: o conhecimento em rela����o ao ��lcool, crack e outras drogas

P��s-gradua����o em Sa��de Coletiva - FMB

Superdota����o e criatividade: an��lise de disserta����es e teses brasileiras

P��s-gradua����o em Educa����o para a Ci��ncia - FC

Tipologias de projetos de pesquisa de m��todos mistos: an��lise classificat��ria das teses de doutorado dos programas de p��s-gradua����o em geoci��ncias no Brasil

Coordena����o de Aperfei��oamento de Pessoal de N��vel Superior (CAPES)

O uso de drogas anticoagulantes e antiplaquet��rias orais em pacientes cir��rgicos ambulatoriais: revis��o de literatura

The oral anticoagulants (AOC) and platelet antiagregants are drugs used for the prevention of thromboembolic phenomena, such as pulmonary embolism in patients with atrial fribrilation heart valves, thrombosis and pulmonary embolism. For patients who are undergoing surgical procedures-dentistry were asked to discontinue the use of anticoagulants until the value of the INR remained = 2.0, that in order to avoid trans and hemorrhages in the postoperative period. However, the AOC can cause the formation of a clot, leading to obstruction of blood pathways. Thus, it became doubtful the medicine for surgery, in which local hemostatic measures would be sufficient to promote hemostasis. Thus, the objective of the review was to evaluate the risk of bleeding in patients AOC users that are subjected to surgical procedures, through a bibliographical survey carried out in relevant clinical studies published between 1990 and 2012, by the MedlinePubMed data. In this review of literature was concluded that the benefit of thromboembolism prevention overcomes the risk hemorrhage, therefore, it is recommended to keep the dose of anticoagulant therapy unchanged for patients undergoing oral surgery and implant dentistry, using appropriate INR levels with the assistance of local hemostatic. In addition, a refined surgical technique should be performed in these patients. With respect to the most invasive oral surgery, with a risk of bleeding, treatment may be necessary in conjunction with the medical staff.

Redes de aten����o �� sa��de para gestantes usu��rias de ��lcool e/ou outras drogas

P��s-gradua����o em Sa��de Coletiva - FMB

Trajet��rias negligenciadas: processos de resili��ncia em adolescentes com hist��rico de envolvimneto no tr��fico de drogas

Funda����o de Amparo �� Pesquisa do Estado de S��o Paulo (FAPESP)

A rela����o do beisebol e as drogas para aumento de desempenho esportivo

O beisebol que possui origens incertas apresenta um grande n��mero de f��s espalhados pelo mundo todo, especialmente em pa��ses como Jap��o e os Estados Unidos, na Am��rica do Sul, h�� a Venezuela e a Col��mbia que se destacam no cen��rio internacional pelo n��mero de atletas em ligas espalhadas pelo mundo. O Brasil apresenta tr��s jogadores atuando na liga americana de beisebol (MLB) atualmente, e no pa��s ainda falta a cria����o de uma liga forte para o desenvolvimento do esporte. As drogas para aumento de desempenho esportivo presente quase que maci��amente no beisebol, durante a era dos ester��ides, per��odo do final dos anos 80 at�� o come��o dos anos 2000, levou a mudan��as em sua pol��tica antidrogas, principalmente na liga americana de beisebol, em uma busca para tornar o esporte limpo. O horm��nio do crescimento e os ester��ides anab��licos androg��nicos foram as drogas mais consumidas pelos atletas durante a era dos ester��ides, no qual n��o havia testes antidoping, e foi justamente nesse per��odo que houve os maiores avan��os nos n��meros ofensivos do esporte, levantando suspeitas sobre as conquistas dos jogadores. Os efeitos adversos e os objetivos dos jogadores de beisebol no uso das drogas para aumento de desempenho esportivo ser��o abordados, assim como as rea����es dos f��s ao doping no esporte. A metodologia foi feita atrav��s da revis��o bibliogr��fica, no qual busquei na literatura existente, e tamb��m em websites, livros, revistas e document��rios esportivos, dados que fornecem informa����es sobre as drogas para aumento esportivo relacionadas ao beisebol, no per��odo de setembro de 2014 a setembro de 2015