Cobalt(III) complexes with thiosemicarbazones as potential anti-Mycobacterium tuberculosis agents

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Revisão sistemática acerca das políticas de educação inclusiva para a formação de professores

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Síntese, caracterização e avaliação da citotoxicidade de complexos de Pd(II) contendo ligantes fosfínicos de N,S - quelantes

Pós-graduação em Química - IQ

O Programa Nacional de Alimentação Escolar (PNAE) no município de Pirapozinho (SP)

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Estudos estruturais por difração de raios X de fosfolipases A2 em presença de íons com importância funcional

Snakes from Bothrops genus are responsible for more than 90% of the ophidian accidents in Brazil. One of the main complications from this kind of accident is muscular necrosis, which is related to the action of phospholipases A2 and metalloproteases, two groups of enzymes found in the venom of these animals. Although this complication cannot be solved by serum therapy administration, a great number of studies have been performed with the attempt to know the pharmacological sites of these toxins aiming, in the future, the development of complementary treatments to serum therapy. This work proposes structural studies of bothropic phospholipases A2 (PLA2s) in the presence of ions relevant to their activity, using the X-ray crystallography technique. Recently, it was demonstrated ions, as manganese, calcium and others, interfere in the biological activity of the PLA2s. Particularly, Lys49-PLA2s in the presence of manganese ions have miotoxicity reduced. Asp49-PLA2s show catalytic activity dependent of calcium, although structural studies with a miotoxic Asp49-PLA2, BthTX-II, suggest a possible catalytic mechanism independent of calcium. Therefore, co-crystallization of BthTX-II in the presence of calcium ions and of PrTX-I in the presence of manganese ions were performed. Comparative structural studies among obtained results and others already published in the literature were performed aiming a better understanding of the structure-function relationship of these toxins. The BthTX-II with the presence of calcium do not show this ion in the loop of coordination of calcium, presence necessary to develop the catalyses. After comparison of this model with the native one, only one distortion was found, but no apparent relationship with the residues responsible for its activity. In the PrTX-I structure, regions candidates of manganese ions were also found... (Complete abstract click electronic access below)

Efeito da prática do futebol no desempenho em agilidade, velocidade e coordenação de meninos na categoria dentinho ou sub 11 (10 e 11 anos de idade)

In Brazil, the practice of Soccer is encouraged very early. It is common remark that parents enroll their sons into soccer schools, promoting the involvement of these children in formal practice. However, there are not many studies that assess the effects of this practice in the physical capacities of children. Thus, the question that guides this study is: children who practice soccer systematically present better development of physical, especially agility, coordination and speed? The objective of this study was to compare the performance in velocity tests, agility and coordination of boys of 10 and 11 years, category dentinho or Sub-11, practitioners of soccer in schools and non practicing. The study included male children, born in 1997 and 1998, formed two groups: group of practitioners of soccer and group of non practicing. To belong to the group of practitioners, the child was regularly engaged for at least 1 year, with 1 hour daily and 2 to 3 times per week. The participants of the group of non practicing were not involved in regular practice of soccer and were paired in weight and stature with participants of the group of practitioners of soccer. Each participant was individually assessed in neutral environment and without foreign interference. For the assessment of the agility, was utilized the (shuttle run) test. The race test 30 meters stopped was employed for the assessment of the speed. The test of fiddling between the cones was employed to measure the coordination. The time spent to perform 1 attempt to each test was used for the comparison between groups. These data were treated, initially, by descriptive statistics (mean and standard deviation) and, subsequently, were compared by means of Anova, for independent samples. The significance level was maintained at 5%. Through analysis of the results the conclusion is that the regular practice ...(Complete abstract click electronic access below)

Contribuições da TIC e da inclusão digital para alunos e professores das escolas participantes do Programa Acessa Escola

This study has its objective to analyze how the Technology of Information and Communication-TIC will be applied in the construction on new knowledge in the schools bounded to the program Acessa Escola.( School turned on) This program from São Paulo’s Government, developed by the Secretary of Education of the State , under the coordination of the Foundation to the Development of the Education-FDE, which has the work proposal to promote the digital inclusion to all the educational community. Making it possible the access of the Technology of Information and Communication to the users; Students, teachers, and school employees to have the exchange of information and knowledge. Therefore, there is the collaboration between teachers and student.For the development of this research, there will be semi-structured interviews with high school teacher from 3 different High Schools of Piracicaba-SP. These interviews will be done in a qualitative approach and will be submitted to the Ethic Committee from the University

A ginástica no ensino fundamental e médio na cidade de Rio Claro/SP: a perspectiva dos alunos

The Gymnastic as a manifestation of the Body Culture Movement should be part of the contents worked in scholar Physical Education, throughout the process of Basic teaching. However, according to studies conducted by researchers from academic Gymnastics school knowledge involving the gymnastics have been tentatively taught in school by numerous factors. For this, the objective of this research was to understand and analyze the opinion of students in middle and high school about gymnastics classes developed with the involvement of graduation scholarship holder and the coordination of the project Gymnastics Goes to School from the UNESP/Campus Rio Claro “Núcleos de Ensino”, in 2012. This research used a questionnaire with topics about the Gymnastic with options: Never Practiced, Like a Lot, Like, Am Indifferent, Dislike, Hate with a space for writing and drawing, relevant to the research objectives. The research was performed with 79 students in middle and high school. With data analysis, it was observed that the students identified themselves more with the Artistic Gymnastic, followed by Rhythmic and Acrobatic Gymnastic and, at last, the General Gymnastic, both through the questionnaire and trough the drawings, which goes against the results from the article published in 2010 by Pereira et al, entitled The students detest the contents gymnastic in physical education classes: motives and alternatives, where the students understand the gymnastics activities only as support, abdominal and stretching. Therefore, to have a real understanding of gymnastics in school, there is a need for teachers to explain and develop the contents gimmicks, so the students could understand the difference among Gymnastics activities and, at the same time, discovering the pleasures of this body practice

Financiamento e convênios na educação infantil: uma análise a partir de periódicos nacionais

This study is bound to the “Research and Studies in Educational Policies”, GREPPE (interinstitutional group) – Rio Claro Section, more accurately to the Research Project entitled Evaluating the scientific production about financing and agreements in childhood education, coordinate by Prof. Dr. Regiane Helena Bertagna, that has as main objective to survey of scientific production at the national level related to the theme of financing and agreements in childhood education in the period from 2000 to 2010. This research has as objective to analyze the financing of childhood education examinee issues of educational policies related to this aspect in this stage of the basic education in national journals. It is intended to ascertain the discussion held in the articles about childhood education financing highlighting the strategies used by the government to offer treatment to the childhood education by means of agreements, or even, by means of public-private partnerships. For the development of this research will be conducted a survey and data analysis from journals of the “Coordination of Improvement of Senior Staff” (CAPES) classified as A2 in the evaluation of 2008. The research will make a cutting between the years from 2000 to 2010; will be analyzed only the national journals online available and that adress the thematic studied

Análise retrospectiva e tendências do serviço de inspeção do estado de São Paulo

Pós-graduação em Medicina Veterinária - FCAV

Implementação de um sistema de aquisição de dados da técnica de judô Osotogari utilizando dummy na realização do uchikomi

Pós-graduação em Engenharia Mecânica - FEG

Complexos heterobilantanídicos luminescentes sob excitação UV e raios X

Pós-graduação em Química - IQ

Escolarização de alunos com altas habilidades/superdotação: um apoio virtual

According to current legislation, is part of the Target of Special Education, students with high abilities/giftedness (HA/G). However, it appears that there are few studies on efficiency and effectiveness of diverse pedagogical practice for students with these characteristics. With increasing globalization, are multiplied opportunities for transnational education programs and educational services, particularly through the Internet, increasing the need for information services and accreditation of institutions and educational programs. This study aims to: a) develop a website containing information on high abilities/giftedness; b) evaluate the design of teachers on applicability of the site; c) analyze the contributions posted on the site. Therefore, it was available to the participants of this research produced site. Consisted on the site, among other information, those relating to HA/G indicators. Was sent a questionnaire via the Internet, with nine closed questions and two open, to 2000 teachers, registered in the database Improvement Course in Educational Practices Inclusive conducted by UNESP, under the coordination of Prof. Dr. Vera Lucia Messias Fialho Capellini. Data were considering frequency responses. For the treatment we used the Google Docs. As result Program Observed how teachers are lacking this subject deserves further Top depth. Concerning the site he was Considered by the participants as a support tool to the teacher, Which helps to identify and recognition of Individuals with HA/G and contributes to information, training and practical pedagogical way. This, is expected to Contribute to the dissemination of this issue in society as well as the Possibility of Minimizing the myths about this population, since such myths exist due to the lack of information

Constrangimentos domésticos à política externa comercial dos Estados Unidos no governo Clinton (1993-2001)

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Grupo Ginástico UNESP: contribuições da Ginástica para Todos na formação de seus participantes

Gymnastics for all or General Gymnastics is a gymnastic body practice without competitive purposes, demonstrative character that combines the basics of gymnastics with different forms of body language. It is a pleasurable physical activity and inclusive, within the gymnastic possibilities offers great opportunities for participation of people, creativity, cooperation and human values experiences (AYOUB, 2003). Within this proposal is, in 2011, the Gymnastic Group UNESP, under the guidance and coordination of teachers Laurita Marconi Schiavon e Silvia Deustch as a project of university extension of the Department of Physical Education, Biosciences Institute of the São Paulo State University / Campus Rio Claro - SP. His working method and choreographic composition based on the proposal of the Gymnastic Group Unicamp, reference in this body practice in Brazil, and their course is in two parts: one for the exploration of all the resources that the teaching materials can provide and the other focused on social interaction of its participants. Therefore the research developed in this study aimed to verify contributions of the participation of members in Gymnastic Group Unesp vocational training thereof, and to verify the relationship and the approach of the members with Gym. The methodological approach adopted for this qualitative research is descriptive, and quantitative and qualitative data collected through questionnaires. The participants were 32 students from different courses at the University, and members of Gymnastic Unesp Group from 2011 to 2013, with the inclusion criteria: 1. minimum of one year of participation in Gymnastic Group Unesp; 2. Minimum of two performances of choreography in events with that group. Quantitative data are processed using descriptive statistics and qualitative analyzed by content analysis technique proposed by Laville and Dionne (1999). According to the results obtained over 41% of the participants had no...