Efficacy of antibiotic therapy for peritoneal dialysis-associated peritonitis: a proportional meta-analysis

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Realismo e impressionismo em contos de Guy de Maupassant

Dans ce texte on a étudié, afin de comprendre et d'analyser les contes réalistes de Guy de Maupassant, comment Erich Auerbach, dans Mimesis (2009), parcourt les sentiers de la littérature occidentale pour dresser un tableau des traits communs qui existent entre les grandes oeuvres réalistes de l'Occident. L'auteur a réalisé des recherches et des commentaires sur les caractéristiques les plus récurrentes du réalisme littéraire dans les oeuvres d'écrivains tels que Homero, Shakespeare, Voltaire, Flaubert, parmi d'autres. Notre recherche vise, dans sa première étape, à présenter, à expliquer ou à identifier dans les contes de Guy de Maupassant, écrivain de la fin du XIXe siècle, les tendances réalistes discutées par ce théoricien et par d'autres au fil du temps, comme, par exemple, Roland Barthes, dans Crítica e verdade (2007), Bersani, dans Le réalisme et la peur du désir (1975) et Philippe Hamon, dans Un discours contraint (1973, p. 411-445). À partir de ces chercheurs, on essaie d'expliciter et d'affirmer le caractère réaliste d'un des maîtres du récit court - sûrement un représentant du réalisme parmi les grands écrivains de cet art - car dans Mimesis (2009) Zola est considéré par Auerbach comme le dernier des grands réalistes français. En plus, pour la deuxième partie de ce travail, on a l'intention de traiter l'émergence de l'impressionnisme artistique en France, et de présenter les concepts et les thèmes qui ont influencé ce mouvement et se présentent dans la construction des récits de Maupassant. Pour le faire, O impressionismo (1962) de Balzi, O impressionismo (1965) de Serullaz, Impressionniste et symboliste devant la presse (1959) de Jacques Lethève, Impressionismo (2010) de Lobstein e autres, mentionnés dans la bibliographie de cette recherche, ont ouvert la voie aux analyses... (Completo abstract click electronic access below)

Cultivo celular in vitro: importância para a pesquisa biomédica e dimensão da problemática de autenticação de linhagens celulares

Experimental models composed by human and animal cell lines are simplified and informative, allowing them to be widely used for biomedical research. Most laboratories that use in vitro cultivated cells maintain a variation of cell lines stored and cultivated. Therefore, misidentification and cross-contamination events can happen during cell lines handling. This problem can generate a repertoire of dubious results and papers, which may prejudice biomedical research. Recently it was created the International Cell Line Authentication Committee (ICLAC), which aims to spread knowledge about cross-contamination and misidentification of in vitro cell lines. Despite of the efforts spent trying to aware scientific community about the importance of the correct identification of cells, the number of papers based on misidentified cell lines it´s still worrying, compromising the reliability of out coming results and conclusions regarding them. The present study aims to analyze and discuss the main advantages and limitations of eukaryote in vitro cell lines use, characterizing the cell lines authentication problems. Therefore, compilation and critical analyses of literature data was realized, aiming to improve the understanding about this subject. Based on information about 445 cell lines with issues published by ICLAC it´s clear that contamination in human cell lines represented 89,2 % of mentioned problems. HeLa cell line was the responsible for most contamination, especially in 92 normal tissue cell lines, representing 44,6% of the contamination. These results reinforce the importance of periodic maintenance of cell lines cultures by labs and implementation of authentication methods as polymorphic STRs, besides obtaining cell lines from reliable sources and cell banks

Os projetos político-pedagógicos dos cursos de pedagogia e os temas ambientais: o caso das Universidades Federais brasileiras

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Educação em saúde em comunidades quilombolas

To appraise the oral health knowledge of parents and children from the quilombola communities located in the Ribeira Valley, Sao Paulo. Methods Preventive and educational activities in oral health were developed with children in the communities (Andre Lopes, Ivaporunduva, Pedro Cubas and Sapatu) including lectures, guidance on tooth brushing techniques, supervised mass brushing, detection of tooth biofilm and topical application of fluoride. Parents also participated in the activities. They were evaluated on the oral health of their children by means of a standard questionnaire. The water supply of the communities was also analyzed. Results The children participated enthusiastically and responsively in the preventive and educational activities. As to the questionnaires, 56% of parents stated that their children’s oral health was poor and 47.2% of them usually follow up on their children’s oral hygiene until they are approximately six years old, but this follow-up is not frequent. Conclusion We conclude that quilombola parents and children have very little knowledge about oral health. Therefore increased attention to oral health is required in these communities by means of frequent oral health education and promotion.

Plantas que atraem aves e outros bichos

Pós-graduação em Ciências Biológicas (Zoologia) - IBB

Uso de áreas agrícolas por Mazama gouazoubira (Mammalia, Cervidae) no Estado de São Paulo

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Measurement of the inclusive 3-jet production differential cross section in proton-proton collisions at 7 TeV and determination of the strong coupling constant in the TeV range

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Automated peritoneal dialysis is associated with better survival rates compared to continuous ambulatory peritoneal dialysis: a propensity score matching analysis

The impact of peritoneal dialysis modality on patient survival and peritonitis rates is not fully understood, and no large-scale randomized clinical trial (RCT) is available. In the absence of a RCT, the use of an advanced matching procedure to reduce selection bias in large cohort studies may be the best approach. The aim of this study is to compare automated peritoneal dialysis (APD) and continuous ambulatory peritoneal dialysis (CAPD) according to peritonitis risk, technique failure and patient survival in a large nation-wide PD cohort. This is a prospective cohort study that included all incident PD patients with at least 90 days of PD recruited in the BRAZPD study. All patients who were treated exclusively with either APD or CAPD were matched for 15 different covariates using a propensity score calculated with the nearest neighbor method. Clinical outcomes analyzed were overall mortality, technique failure and time to first peritonitis. For all analysis we also adjusted the curves for the presence of competing risks with the Fine and Gray analysis. After the matching procedure, 2,890 patients were included in the analysis (1,445 in each group). Baseline characteristics were similar for all covariates including: age, diabetes, BMI, Center-experience, coronary artery disease, cancer, literacy, hypertension, race, previous HD, gender, pre-dialysis care, family income, peripheral artery disease and year of starting PD. Mortality rate was higher in CAPD patients (SHR1.44 CI95%1.21-1.71) compared to APD, but no difference was observed for technique failure (SHR0.83 CI95%0.69-1.02) nor for time till the first peritonitis episode (SHR0.96 CI95%0.93-1.11). In the first large PD cohort study with groups balanced for several covariates using propensity score matching, PD modality was not associated with differences in neither time to first peritonitis nor in technique failure. Nevertheless, patient survival was significantly better in APD patients.

Healing and expression of growth factors (TGF-β and PDGF) in canine radial ostectomy gap containing platelet-rich plasma

Objectives: To evaluate bone healing in an experimental radial ostectomy in dogs treated with autologous platelet-rich plasma (PRP), through histological, densitometric, radiographic studies, as well as expression of growth factors in the ostectomy gap. Methods: Twenty-one dogs were randomly divided into either a control or a PRP group. All underwent unilateral ostectomy of the radius to generate a gap of 2.0 mm, that was stabilized with external skeletal fixation. The ostectomy gap was either filled with PRP or left empty as a control. The radiographic and densitometric studies were performed after surgery, then at intervals until 60 days during the post-surgery period. Histological and immunohistochemical evaluations were performed at seven or 60 days post-surgery. Analyses were performed using a statistical analysis system, and the level of significance was set at p <0.05. Results: The median radiographic healing score in the PRP group increased significantly between day 0 and day 60. Furthermore, at 60 days, the median healing score and the proportion of healed ostectomies in the control group (score 1; 1/6 healed) and the PRP group (score 5; 4/5 healed) were significantly different. There were differences between groups in radiographic and densitometric values at days 45 and 60. The histological evaluation showed advanced bone healing at 60 days in the PRP group and signs of delayed union in the control group. Clinical relevance: Platelet-rich plasma can be used as an adjuvant therapy because it may promote better bone healing of a radial ostectomy treated with external skeletal fixation in dogs.

Storage media for avulsed teeth: a literature review

Dental avulsion is the most severe type of traumatic tooth injuries because it causes damageto several structures and results in the complete displacement of the tooth from its socketin the alveolar bone. The ideal situation is to replant an exarticulated tooth immediatelyafter avulsion because the extraoral time is a determinant factor for treatment successand for a good prognosis. However, it is not always possible. The success of replantationdepends on a number of factors that may contribute to accelerate or minimize theoccurrence of root resorption or ankylosis, among which is the type and characteristicsof the medium used for temporary storage during the time elapsed between avulsionand replantation. Maintaining the tooth in an adequate wet medium that can preserve,as longer as possible, the vitality of the periodontal ligament cells that remain on rootsurface is the key to success of replantation. Recent research has led to the developmentof storage media that produce conditions that closely resemble the original socketenvironment, with adequate osmolality (cell pressure), pH, nutritional metabolites andglucose, and thus create the best possible conditions for storage. Although these storagemedia can now be purchased in the form of retail products, the most common scenariois that such a product will not be readily available at the moment of the accident Thispaper reviews the literature on the different storage media that have been investigatedfor avulsed teeth based on full-length papers retrieved from PubMed/Medline, Lilacs, BBOand SciELO electronic databases using the key words storage medium , transportationmedium , avulsion , tooth avulsion , replantation , tooth replantation , milk and propolis .After application of inclusion and exclusion criteria, 39 papers were selected and criticallyreviewed with respect to the characteristics, efficacy and ease of access of the storagemedium. The review of the lite

Diversidade genética em populações de Candidatus Liberibacter asiaticus determinada por marcadores SSR

Pós-graduação em Agronomia (Genética e Melhoramento de Plantas) - FCAV

Avaliação da atividade antiviral dos compostos do esmalte de unha (acetato de etila e acetato de butila) no herpesvírus bovino tipo 5

Pós-graduação em Enfermagem - FMB