Hepatitis C virus and dental health workers: an update

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Notificações espontâneas de eventos adversos a medicamentos hospitalares: estudo piloto

Introduction: Post-marketing surveillance of drugs aims to detect problems related to safety, effectiveness and quality. The identification of adverse drug events (ADE) is made, mainly, by health professionals´ spontaneous reporting. This method allows risk communication in pharmacovigilance and contributes for market regulation. Objective: To estimate the prevalence of adverse drug reaction (ADR) and the suspicions of therapeutic failure (TF) reported by health professionals; to verify the active principle and type of drugs related to ADE, seriousness, causality, production mechanism and clinical manifestation of the events identified. METHODS: A cross-sectional study was performed in a teaching and public hospital which integrates the Sentinel Hospital Network, in 2008. ADR seriousness was classified according to intensity (mild, moderate, serious and lethal); drugs associated with ADE were categorized according to type (brand name drugs and non-brand name drugs); causality was imputed with Naranjo algorithm and the mechanism of occurrence was analyzed according to Rawlins e Thompson definitions (A or B). Results: There were 103 ADE reports in the period, of which 39 comprised TF and 64 ADR. Nurses reported the most ADE (53.4%). The majority of ADR were classified as type A (82.8%), mild (81.3%), possible (57.8%), according to causality assessment, and related to brand name drugs (20/35). Human immunoglobulin, docetaxel and paclitaxel were the drugs frequently associated with ADR. TF arising from no-brand name drugs (26/29), regarding, mainly, midazolam and ganciclovir. Conclusion: The results of the ADE report contribute for proposition of trigger tools for intensive monitoring of drug safety, as well as for the supplier qualification and for the improvement of quality products.

Medicamentos inadequados para idosos na estratégia da saúde da família

The ageing process can change the pharmacodynamics and pharmacokinetics parameters. Therefore, some medications are considered potentially inappropriate (PIM) for the elderly people, since they can increase the likelihood of occurrence of adverse drug events. The objectives are to estimate the frequency of use of PIM in the elderly people, with potentially hazardous drug interactions (PHDI) and to evaluate the impact of pharmaceutical intervention (PI) for the prescription of safer therapeutic alternatives. A cross-sectional study was performed in a Health Family Strategy (region of Araraquara, SP), between January and February/2012. The medical records of patients aged ≥60 years, that use at least one drug, were consulted for identification of PIM, according to the Beers criteria. The MPI identified were classified considering the Anatomical Therapeutic Chemical Classification System (ATC) and the essentiality of the drug (safety, effectiveness, quality and cost parameters) The inclusion criteria were met by 358 elderly, being that 93 of them (26%) had taken at least one PIM. Of the 114 different drugs prescribed for elderly, ten were classified as PIM, of which four of them act on the central nervous system, four on cardiovascular system and two on the digestive tract. Seven MPI are essential medicines, belonging to national list of essential drugs (RENAME-2010). Fourteen drug interactions were identified, of which two are PHDI (fluoxetine/amitriptyline and digoxin/hydrochlorothiazide).After the PI, there was no change in medical prescriptions of patients with PIM use or with DI. Medical prescriptions of elderly attended in the Health Family Strategy show pharmacotherapeutic safety problems, of which may be responsible for health hazardous for this age group. Although the intervention carried out by letter had been ineffective for the adherence of doctors in prescribing safe alternatives, wide dissemination of the lists that contain PIM and PHDI is need, as well as the inclusion of safer equivalents in RENAME, in order to contribute for rational use of drugs.

Identificação de bandas espectrais para detecção de cultura de cana-de-açúcar sadia e doente utilizando câmara hiperespectral embarcada em VANT

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Avaliação ambiental simplificada dos recursos hídricos na bacia hidrográfica do Ribeirão Preto, São Paulo

The objective of this study was to evaluate environmental impacts on the Ribeirão Preto basin in order to define the most degraded areas and their causes and to propose solutions and management strategies for them. An impacts indicator questionnaire was designed, that allowed us to establish a direct relationship between reactions achieved and environmental factors by attributing value to some impacting parameters obtained by simple visualization in the field. The questionnaire was applied at 22 points, based on the influence area of the sub-basin and variability in land use. It was determined that the main environmental impacts that affect the basin are in nature effluent wastewater released into water bodies, the disposal of waste and deforestation. These factors were mainly noticed near to Ribeirão Preto city (State of São Paulo), the most populated region. Such information provides subsidies necessary to environmental management in this basin to decreasing environmental degradation. Among the management strategies suggested, it is possible to highlight that related to the accomplishment of environmental legislation, recuperation of degraded areas and adequate treatment and disposal of effluents.

Impactos ambientais na bacia hidrográfica do Ribeirão Monjolo Grande, Ipeúna, SP

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Comunicação pública, transparência e políticas públicas: avaliação de informações em portais brasileiros de governo

An expansion of the professional field of Public Relations can be seen nowadays, influenced by factors such as the increasing use of information and communications technologies for the dissemination of information on public management and the potential creation of dialogue between government and citizens. Despite this trend, there is still a need for specific knowledge about normative aspects of public communication generated by governments on the internet and its role in the fulfillment of the right to information. This article offers a contribution to fulfill the gap of guidelines and standards for professional performance. It describes the results of empirical research which identified the potential contribution of government web portals of the main cities of São Paulo, in the southeastern Brazil, to the strengthening of citizenship, considered in its dimension of exercising the right to information about public policies, particularly those which have an impact on education. The depth and breadth of information were investigated according with twelve categories of evaluation: history; diagnoses; goals; goals; resources and current actions; planned resources and actions; efficiency; effectiveness; impact; cost-effectiveness; user satisfaction; and equity. The data found on the analyzed portals correspond to the average of 11% of which was considered, under the theoretical-methodological context of the research, as information necessary to comprise the full characterization of a public policy in relation to the categories of assessment. Opportunities to improve government web portals were detected, for which we suggest communication management strategies.

A importância de ações estratégicas de gestão de pessoas no manejo do estresse e de estressores ocupacionais

The introducing of new technologies at work contexts forces the contemporary organizations to search new structures and productive processes, as well as new management models, mainly personnel management. A strong pressure by positive results can favour health problems concerning to stress, which is caused by a highly competitive environment; studies reveals that stress is a present reality at organizations nowadays. The presence of stress on workers cause harm to organizations (due to absenteeism increasing, turnover, interpersonal conflicts, etc.) and individuals, whose life quality can be decreased. This text intends to highlight the importance of identifying stress presence on workers and eventual stressors at workplaces, with the objective of, through management strategies, propose interventions guided to promote occupational health and welfare. Identifying eventual stressors at workplaces becomes an essential task, because those signs predispose the stress presence on workers. Therefore, discovering them is a strategic way to preventing and managing of occupational stress. This text also proposes to show some personnel management strategies which can favour the prevention of occupational stressors, as well as interventions on them.

Ecologia química no controle biológico de fitófagos e respectivos predadores e parasitoides

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Fisiologia e bioquímica do tomateiro submetido à irrigação salina parcial do sistema radicular

Pós-graduação em Agronomia (Produção Vegetal) - FCAV

Análise organizacional de acidentes de trabalho no setor de distribuição de energia elétrica

Pós-graduação em Saúde Coletiva - FMB