116 resultados para intensidade emocional
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Haloperidol is a dopamine receptor antagonist used to treat schizophrenia. When systemically administered in rodents, haloperidol induces catalepsy, a state of immobility very similar to that seen in Parkinson's disease. It is known that many of Parkinson's disease symptoms are dependent on the emotional state since patients are still able to respond to external triggers such as loud noise or visual signaling. Recent data highlighted the importance of glutamatergic neurotransmission in the inferior colliculus (IC) on the cataleptic state induced by haloperidol in rats. Given the importance of IC in the brain aversion system and its connections to motor pathways, and based on the clinical reports of the emotional influence on the motor aspect of Parkinson's disease, the objective of the present study was to evaluate the emotional aspect related to catalepsy induced by intraperitoneal administration of haloperidol. To this end, we analysed ultrasonic vocalizations (UVs) of 22 kHz (indicative of aversion) in rats during the tests of catalepsy, open field and contextual conditioned fear. Systemic administration of haloperidol affected the motor activity, inducing catalepsy and decreasing exploratory activity in the open field. There were no UVs of 22 kHz resulting from treatment with haloperidol in catalepsy or open field tests. In the contextual conditioned fear test, haloperidol increased freezing when administered before the test, but decreased freezing on test day when administered before training. In this same test, haloperidol decreased the UVs on the day it was administered (training or test). The catalepsy induced by systemic administration of haloperidol seems to have also affected the motor aspect of UVs. In this way, it was not possible to clarify the existence of an aversive emotional state associated haloperidol induced catalepsy
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Pós-graduação em Educação - FFC
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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This academic report presents results of the research developed between 2012 and 2015, and it had as main goal the development of new mapping possibilities of the central areas of the cities of Marília/SP, São Carlos/SP and São José do Rio Preto/SP. We developed this research using mostly the database from Cadastro Nacional de Endereços Para Fins Estatísticos (CNEFE), and after processing the information, it was added the typology established in the Cadastro Nacional de Atividades Econômicas (CNAE). This database, after the final treatment process, provided us information that made possible the production of thematic maps which are used to study central areas, allowing the analysis of spatial logics of companies, the identification of concentration and dispersion of economic activities, arrangement of specialized axis, expansion of the central area, reorganization of the city, among other process and phenomena
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The industry generally has sought materials with high mechanical resistance, low density, thermal stability and corrosion resistance. In the aerospace industry, for example, the use of aluminum alloys, such as Al 2024-T351 and Al 7075-T7351, have become essential. However, the use of these materials often do not resulted in a satisfactory performance of the component, since the presence of cracks can cause total rupture of the component, even with a tension below the yield stress of the material, unexpectedly. In this work, these aluminum alloys were analyzed and samples were modeled by the finite element method. Moreover, in the models were applied two different types of cracks, central and edge crack, a vertical force was applied to result in a tension 70% of the yield stress of the material analyzed. Through stress asymptotic distribution in the region near the crack tip were calculated the values of the stress intensity factors for each crack length, after the stress intensity factors characterized were compared graphically with the values of fracture toughness found in the available literature
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Pós-graduação em Ciências da Motricidade - IBRC
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Esta revisão avaliou a eficácia da utilização da vacina E. coli J5, na imunização de vacas e novilhas leiteiras no pós-parto, em relação à prevenção de novos casos de mastite clínica, redução na gravidade dos sinais clínicos dos animais acometidos pela enfermidade, assim como na contagem de células somáticas presentes no leite dos animais doentes. O experimento contou com a avaliação dos dados encontrados em seis trabalhos científicos, divididos em dois grupos, três com estudos em vacas e três com estudos em novilhas. A prevenção de casos de mastite clínica foi observada somente em vacas; no grupo das novilhas não houve diferença entre vacinados e não vacinados. Em relação à gravidade dos sinais clínicos dos animais acometidos com mastite, tanto no grupo das novilhas quanto no das vacas, a vacina mostrou-se eficaz, reduzindo custos com tratamentos, descarte de leite e de animais. Sobre a eficácia da vacina em reduzir contagem de células somáticas presentes no leite dos animais com mastite, a vacina não se mostrou eficaz em vacas e novilhas. Análise econômica indica que a vacina E. coli J5 é lucrativa para produtores de leite de grande, médio e pequeno porte, sendo recomendada tanto para vacas quanto para novilhas, por reduzir os custos de produção e facilitar o manejo das granjas leiteiras
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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Pós-graduação em Odontologia - FOA
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BACKGROUND AND OBJECTIVES: Vaginal birth delivery may result in acute and persistent perineal pain postpartum. This study evaluated the association between catastrophizing, a phenomenon of poor psychological adjustment to pain leading the individual to magnify the painful experience making it more intense, and the incidence and severity of perineal pain and its relationship to perineal trauma. METHOD: Cohort study conducted with pregnant women in labor. We used the pain catastrophizing scale during hospitalization and assessed the degree of perineal lesion and pain severity in the first 24 hours and after 8 weeks of delivery using a numerical pain scale. RESULTS: We evaluated 55 women, with acute pain reported by 69.1%, moderate/severe pain by 36.3%, and persistent pain by 14.5%. Catastrophizing mean score was 2.15 ± 1.24. Catastrophizing patients showed a 2.90 relative risk (RR) for perineal pain (95% CI: 1.08-7.75) and RR: 1.31 for developing persistent perineal pain (95% CI: 1.05-1.64). They also showed a RR: 2.2 for developing acute and severe perineal pain (95% CI: 1.11-4.33). CONCLUSIONS: The incidence of acute and persistent perineal pain after vaginal delivery is high. Catastrophizing pregnant women are at increased risk for developing acute and persistent perineal pain, as well as severe pain. Perineal trauma increased the risk of persistent perineal pain.
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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Bruxism is the harmful habit of clenching or grinding the teeth during the day and / or night, with unconscious pattern, with particular intensity and frequency, outside the functional movements of chewing and swallowing. It is accepted that bruxism is a response controlled by the neurotransmitters dopamine system associated with emotional component. The proposed of treatment of bruxism with acupuncture aims to stimulate sensory fibers of the peripheral nervous system leading to electrical transmission by neurons sufficient to produce changes in the central nervous system. As a consequence there is the release of substances (cortisol, endorphins, dopamine, noradrenaline and serotonin) that promote wellness and restoration of harmony, be it psychological, biological and / or behavioral.