Própolis bruta em dietas para tilápia-do-nilo e ação antimicrobiana frente à Aeromonas hydrophila

Pós-graduação em Zootecnia - FMVZ

Variáveis hematológicas, hormonais, bioquímicas séricas e fauna parasitária em quatro espécies de raias do gênero Potamotrygon Garman, 1877 (Myliobatiformes, Potamotrygonidae) de vida livre

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Diagnóstico molecular de hemoparasitas e frequência de anticorpos anti-Toxoplasma gondii e anti-Neospora caninum, em gatos peridomiciliados na cidade de São Luís, Maranhão

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Estudo do potencial genotóxico da Gutiferona A em diferentes células de camundongos in vitro

Pós-graduação em Biologia Geral e Aplicada - IBB

Variação da ecogenicidade difusa em parênquima hepático homogêneo relacionada aos achados bioquímicos e hematológicos em cães

The present study evaluated the liver with homogeneous parenchyma in dogs, with diffuse reduced echogenicity (G1), increased echogenicity (G2) and normal echogenicity (G3) by ultrasound examination associating the findings on animal profile, liver size and hematology and biochemistry results. Blood samples obtained by cephalic or jugular venipunture were submitted for hemogram and ALT, ALP, total proteins, albumin, globulin, urea and creatinine analysis. Among the 30 dogs in G1, 30 (100%) presented portal venous and gall bladder wall clarity, 23 (76.67%) presented normal liver size and edges, 15 (50%) were from 1 to 6 years old and 8 (26.67%) belonged to the lhasa apso breed. No predispositions were found according to gender, as well as no significant alterations in biochemical and hematological exams were observed in G1. The most prevalent disease found in this group was gastroenteritis (43.33%). Among the 30 dogs in G2, 27 (90%) presented hepatomegaly and rounded hepatic edges, 18 (60%) were over 9 years old, 16 (53.33%) were female and 9 (30%) belonged to the poodle breed. The laboratorial findings related to this group were increased ALT and ALP serum activity, decreased levels of total protein, albumin, globulin, erythrocytes and hematocrit, as well as leukocytosis with neutrophilia and a left shift, eosinopenia, lymphopenia and monocytosis. The most prevalent diseases found in this group were metabolic disorders (54%), such as diabetes mellitus and hyperadrenocorticism, and chronic hepatopathies (17%) due to prolonged and continuous use of corticoid and anticonvulsive drugs. Among the 30 dogs in the control group (G3), normal liver size and edges were presented in 22 (73.33%). In this group, no alterations were seen in laboratorial exams.

Pesque-solte: pesca repetitiva, variáveis hematológicas e parasitismo no peixe híbrido tambacu

The objective of this work was to evaluate the hematological and parasitological responses of tambacu (Colossoma macropomum x Piaractus mesopotamicus) subjected to catch-and-release stress and to different stocking densities in a catch-and-release system. Two hundred and ten fish with mean initial weight of 785.33±152.02 g and mean total length of 34.43±2.21 cm were maintained in ponds and divided into three groups: without fishing and low density (G1), with fishing and low density (G2), and with fishing and high density (G3). No significant differences were observed between the mean values for hemoglobin concentration, erythrocyte number, differential counting of leukocytes, and glucose. The fish from the G3 group showed higher parasite and thrombocyte numbers, and lower weight gain and hematocrit. The activity of catch-and-release, associated with high stocking density, can disrupt organic balance and animal performance, favoring parasitosis.

Variáveis hematológicas em tambaquis anestesiados com óleo de cravo e benzocaína

The objective of this work was to evaluate the anesthetic effect of clove oil and benzocaine on the hematology and osmotic fragility of erythrocytes in tambaqui (Colossoma macropomum). Thirty adult fish were evaluated in three treatments: a control, without anesthetic; anesthesia with clove oil at 50 mg L-1; and anesthesia with benzocaine at 100 mg L-1. Blood was collected for hemogram determination, and a test for the erithrocyte osmotic-fragility was applied. The utilized doses of clove oil and benzocaine are not appropriate for hematologic studies to establish reference values for tambaqui because they cause significant changes of the hematologic parameters, such as leukocytosis and iatrogenic hemolysis.

Treinamento individualizado aeróbio, resistido e concorrente: efeitos sobre os marcadores de estresse oxidativo em ratos Wistar

Pós-graduação em Ciências da Motricidade - IBRC

Síntese e avaliação farmacológica de novos compostos híbridos úteis para tratamento das complicaçôes da anemia falciforme

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Avaliação de sistemas lipidicos nanoestruturados utilizados como estratégia para melhorar as propriedades biofarmaceuticas do praziquantel no tratamento da esquistossomose

Pós-graduação em Nanotecnologia Farmacêutica - FCFAR

Avaliação de biomarcadores inflamatórios moleculares em pacientes com câncer de mama

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Avaliação de biomarcadores moleculares em mulheres com câncer de ovário

Pós-graduação em Ginecologia, Obstetrícia e Mastologia - FMB

Clinical, biochemical and haemathological effects in Rhamdia quelen exposed to cypermethrin

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Antimalarial activity of piperidine alkaloids from Senna spectabilis and semisynthetic derivatives

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Avaliação do potencial genotóxico e mutagênico do efluente de uma refinaria de petróleo e dos rios sob sua influência, por meio de bioensaios com Oreochromis niloticus (Perciformes, Cichlidae)

The petrochemical industry represents a sector of intense activity, in constant expansion and great economic importance for Brazil. In order to be used in various human activities petroleum needs to suffer a refinement process that, besides requiring large amounts of water, produces large amounts of wastes, which are discharged in hydric resources. Petroleum is a complex mixture mainly comprised by hydrocarbons, many of them are recognized as toxic chemicals, which are able to induce a considerable environmental pollution. Since water is an important resource for the maintenance of ecosystems and is also the final receiver of effluent discharges of the petroleum industry, there is an imminent need to monitor, constantly, the hydric resources that are influenced by this industrial activity, so that it can be ensured the environmental health. This study aimed, mainly, to analyze the quality of water samples derived from refinement process performed of the largest petroleum refinery in Brazil (REPLAN), in distinct steps of the industry treatment, and waters of rivers associated to its activity. Micronuclei and Nuclear Abnormalities tests were performed in erythrocytes of the fish species Oreochromis niloticus exposed to water samples derived from refinery use and to rivers under the influence of their effluents, in order to evaluate its possible toxic, genotoxic and mutagenic effects. The results obtained show that the treatment carried out by the refinery, during the evaluated periods, was effective, since the substances present in the water samples did not induce significant genotoxic and/or mutagenic alterations in the genetic material of the test organisms. On the other hand, when the substances present in the refinery effluent mix with the ones derived from other industrial activities developed upstream of this industry, the resultant compound, in some periods, presented genotoxic potencial, characterized by a rise of erythrocytic...