Concentração plasmática de diclofenaco sódico em cães, submetidos à fonoforese

The aim of this study was to evaluate the plasma concentration of diclofenac sodium (DS) in dogs submitted to diclofenaco phonophoresis and to evaluate if phonophoresis induces greater absorption of this drug in dogs. Five dogs were used in eight different groups at different times: One group received oral administration of 40mg of DS per dog and seven groups received topical application of emulgel DS. The topical application area was 20cm(2). A continuous ultrasound frequency of 1MHz and intensity of 0.4W cm(-2) was used. Blood collections were performed before the treatment (T0), and 1h (T1) and 4h (T2) after ultrasound application for all groups. DS concentrations in plasma were measured by high performance liquid choramatohraphy (HPLC). There was significant increase of DS plasma concentration only at T1 in the oral administration group. It was not possible to detect any concentration of DS in the plasma of dogs after topical application of DS, even after DS phonophoresis. The facilitation of transdermal penetration by ultrasound has not been verified under the protocol specified in this research.

Slow-fast systems on algebraic varieties bordering piecewise-smooth dynamical systems

This article extends results contained in Buzzi et al. (2006) [4], Llibre et al. (2007, 2008) [12,13] concerning the dynamics of non-smooth systems. In those papers a piecewise C-k discontinuous vector field Z on R-n is considered when the discontinuities are concentrated on a codimension one submanifold. In this paper our aim is to study the dynamics of a discontinuous system when its discontinuity set belongs to a general class of algebraic sets. In order to do this we first consider F :U -> R a polynomial function defined on the open subset U subset of R-n. The set F-1 (0) divides U into subdomains U-1, U-2,...,U-k, with border F-1(0). These subdomains provide a Whitney stratification on U. We consider Z(i) :U-i -> R-n smooth vector fields and we get Z = (Z(1),...., Z(k)) a discontinuous vector field with discontinuities in F-1(0). Our approach combines several techniques such as epsilon-regularization process, blowing-up method and singular perturbation theory. Recall that an approximation of a discontinuous vector field Z by a one parameter family of continuous vector fields is called an epsilon-regularization of Z (see Sotomayor and Teixeira, 1996 [18]; Llibre and Teixeira, 1997 [15]). Systems as discussed in this paper turn out to be relevant for problems in control theory (Minorsky, 1969 [16]), in systems with hysteresis (Seidman, 2006 [17]) and in mechanical systems with impacts (di Bernardo et al., 2008 [5]). (C) 2011 Elsevier Masson SAS. All rights reserved.

O lirismo em György Lukács

The paper aims to examine the treatment of lyrical in the aesthetics work of the young Lukacs. In The Soul and the Forms the author examines the poetry of Stefan George, finding on it formal elements that point out to the emergence of a new lyricism. This "significant form" allows the author to introduce an approach of the concept of modernity, in critical and phenomenological bias. Work that will be completed in The theory of Love, when the lyric trend will be exacerbated, contaminating and altering the settings of the other genera.

A Note on the Prior Distributions of Weibull Parameters for the Reliability Function

In Bayesian Inference it is often desirable to have a posterior density reflecting mainly the information from sample data. To achieve this purpose it is important to employ prior densities which add little information to the sample. We have in the literature many such prior densities, for example, Jeffreys (1967), Lindley (1956); (1961), Hartigan (1964), Bernardo (1979), Zellner (1984), Tibshirani (1989), etc. In the present article, we compare the posterior densities of the reliability function by using Jeffreys, the maximal data information (Zellner, 1984), Tibshirani's, and reference priors for the reliability function R(t) in a Weibull distribution.

Relacoes entre a concentracao espacial dos ramos industriais 'motrizes' e o desenvolvimento regional: o caso do Estado de Sao Paulo.

This paper, having its conceptual basis in the Theory of Growth Poles, by F.Perroux, tests the effective existence of correlation between the spatial incidence and concentration of the 'propulsive' industrial groups and the industrial growth as a whole and the demographic increase. The selected case study was the state of Sao Paulo and data used was the 1970 census. As consequence of the techniques applied a industrial regionalization of the 'paulista' space was obtained, showing few areas of intense industrial concentration, especially of 'propulsive' groups, with multiple growth poles, and large areas with industrial rarefaction, with little or no poles.-after English summary

VSSI X̄ charts with sampling at fixed times

A standard X̄ chart for controlling the process mean takes samples of size n0 at specified, equally-spaced, fixed-time points. This article proposes a modification of the standard X chart that allows one to take additional samples, bigger than n0, between these fixed times. The additional samples are taken from the process when there is evidence that the process mean moved from target. Following the notation proposed by Reynolds (1996a) and Costa (1997) we shortly call the proposed X chart as VSSIFT X chart where VSSIFT means variable sample size and sampling intervals with fixed times. The X chart with the VSSIFT feature is easier to be administered than a standard VSSI X chart that is not constrained to sample at the specified fixed times. The performances of the charts in detecting process mean shifts are comparable. Copyright © 1998 by Marcel Dekker, Inc.

Gravity and the quantum: Are they reconcilable?

General relativity and quantum mechanics are not consistent with each other. This conflict stems from the very fundamental principles on which these theories are grounded. General relativity, on one hand, is based on the equivalence principle, whose strong version establishes the local equivalence between gravitation and inertia. Quantum mechanics, on the other hand, is fundamentally based on the uncertainty principle, which is essentially nonlocal. This difference precludes the existence of a quantum version of the strong equivalence principle, and consequently of a quantum version of general relativity. Furthermore, there are compelling experimental evidences that a quantum object in the presence of a gravitational field violates the weak equivalence principle. Now it so happens that, in addition to general relativity, gravitation has an alternative, though equivalent, description, given by teleparallel gravity, a gauge theory for the translation group. In this theory torsion, instead of curvature, is assumed to represent the gravitational field. These two descriptions lead to the same classical results, but are conceptually different. In general relativity, curvature geometrizes the interaction while torsion, in teleparallel gravity, acts as a force, similar to the Lorentz force of electrodynamics. Because of this peculiar property, teleparallel gravity describes the gravitational interaction without requiring any of the equivalence principle versions. The replacement of general relativity by teleparallel gravity may, in consequence, lead to a conceptual reconciliation of gravitation with quantum mechanics. © 2006 American Institute of Physics.

Jacobi script v sign-functions and discrete Fourier transforms

Properties of the Jacobi script v sign3-function and its derivatives under discrete Fourier transforms are investigated, and several interesting results are obtained. The role of modulo N equivalence classes in the theory of script v sign-functions is stressed. An important conjecture is studied. © 2006 American Institute of Physics.

Quantum entanglement and information: The effect of entropy revisited

In non-extensive statistical mechanics [14], it is a nonsense statement to say that the entropy of a system is extensive (or not), without mentioning a law of composition of its elements. In this theory quantum correlations might be perceived through quantum information process. This article, that is an extension of recent work [4], is a comparative study between the entropies of Von Neumann and of Tsallis, with some implementations of the effect of entropy in quantum entanglement, important as a process for transmission of quantum information. We consider two factorized (Fock number) states, which interact through a beam splitter bilinear Hamiltonian with two entries. This comparison showed us that the entropies of Tsallis and Von Neumann behave differently depending on the reflectance of the beam splitter. © 2011 Academic Publications.

Divergences of generalized quantum electrodynamics on the Lorenz gauge

In this paper we study the Generalized Quantum Electrodynamics (GQED4) on the Lorenz gauge condition and show that divergences are still present in the theory. © 2013 American Institute of Physics.

Construções de reticulados via extensões cíclicas de grau ímpar

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Duas formas da recepção das idéias de Lukács no Brasil: estética e ontologia

Pós-graduação em Ciências Sociais - FFC

O setor sucroenergético no Brasil: Estado, hegemonia e relações internacionais - o caso da UNICA no agribusiness internacional

Pós-graduação em Ciências Sociais - FFC

Festa do tropeiro de silveiras: uma abordagem folkcomunicacional

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Ler e escrever: mediação entre crianças pequenas

Pós-graduação em Educação Escolar - FCLAR