Defining suitable reference genes for RT-qPCR analysis on human sertoli cells after 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposure

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Treatment with tacrolimus enhances alveolar bone formation and decreases osteoclast number in the maxillae: A histomorphometric and ultrastructural study in rats

Recent studies have suggested that tacrolimus monotherapy is a beneficial therapeutic alternative for the normalization of cyclosporin- induced bone loss in animal models and humans. The mechanism accounting for this action is unclear at present. In the present study, we attempted to determine the effect of tacrolimus monotherapy on alveolar bone using histological, histomorphometrical and transmission electron microscopy (TEM).Groups of rats (n= 10 each) were treated with either tacrolimus (1mg/ kg/ day, s.c.) or drug vehicle for 60 days. Fragments containing maxillary molars were processed for light microscopy to investigate the alveolar bone volume, trabecular separation, number of osteoclasts and osteoblasts, and transmission electron microscopy to investigate their ultrastructural basic phenotype.Treatment with tacrolimus monotherapy during 60 days may induce increases in alveolar bone volume (BV/ TV,%; P < 0.05) and a non- significant decrease in trabecular separation (Tb. Sp, mm; P > 0.05), represented by a decrease in osteoclast number (N. Oc/ BS; P < 0.05) and maintenance of osteoblast number (N. Ob/ BS; P > 0.05). Osteoblasts were often observed as a continuous layer of active cells on the bone surface. Osteoclasts appeared to be detached from the resorbed bone surface, which was often filled by active osteoblasts and collagen- rich matrix. Moreover, osteoclasts in the treated group were frequently observed as inactive cells (without ruffled border, clear zone and detached from the bone surface).Within the limits of the present study, we conclude that tacrolimus leads to an increase in alveolar bone formation, which probably exerts action on osteoclasts. Tacrolimus could, therefore, play a crucial role in the control of both early osteoclast differentiations from precursors, as well as in functional activation.

Caracterização e mapeamento da cultura da cana-de-açúcar no município de Rio Claro (SP) por meio de técnicas de sensoriamento remoto e sistemas de informações geográficas

This paper discusses about the use of remote sensing image and processing digital images tools for mapping and assessing the effect on the biomass of the culture of sugar cane in the city of Rio Claro. We used satellite images from CBERS in the passages of 19/04/2009 and 23/09/08, which correspond respectively to the stages where the sugar cane appeared in growing and adult pre-harvest stage. In these images, we applied procedures of digital processing, as the application of the procedures for extending linear contrast, radiometric normalization, Normalized Vegetation Index (NDVI) and pixel by pixel classification by ISOSEG through of the software SPRING. As a result we obtained mapping of the distribution and development stages of the culture of sugar cane in the city of Rio Claro and the mapping of the existing biomass of this culture, showing that the method used to assess the relative effect on biomass in culture of sugar cane was efficient, and that images of low-medium resolution are not the most suitable for the mapping of this culture

Uma análise da tradução de vocábulos relacionados à violência e criminalidade presentes em três obras de Patrícia Melo

Pós-graduação em Estudos Linguísticos - IBILCE

Uma investigação de aspectos de normalização na autotradução An Invincible Memory

This paper aims at observing the particular case of an author’s and self-translator’s style concerning normalisation features present in the self-translation. Our study has its theoretical starting point based on Baker’s proposal (1993, 1995, 1996, 2000) and Scott’s investigation in order to carry out an analysis of the use of linguistic choices involving evidence of normalization. The results point out that, while participating as a self-translator, Ubaldo Ribeiro reveals individual, distinctive and preferred stylistic options which present less lexical variation; in contrast, in the situation of participating as an author, Ubaldo Ribeiro shows stylistic choices of higher lexical diversity. Observed normalisation features reveal conscious or subconscious use of fluency strategies, making the target text easier to read. Due to his renowned sound command of the target language, the results may also suggest the challenges during the translated text re-creation process faced as a self-translator could have been greater than the challenges during the previous original text creation process faced as an author

Tendências de normalização na tradução para o inglês da obra As Mulheres de Tijucopapa

The present essay aims at observing possible tendencies of normalization by the translator Irene Matthews in the translation to English from As mulheres de Tijucopapo, by Marilene Felinto. The methodology employed is that of corpus-based translation studies (proposed by BAKER, 1993, 1995, 1996, 2000; SCOTT’s study concerning normalization, 1998; and CAMARGO’s research studies, 2005, 2007), and that of corpus linguistics (BERBER SARDINHA’s studies, 2003, 2004). The investigation was carried out by means of a combination of semi-manual and computerized analyses using the computer software WordSmith Tools. Based on Scott (1998), we analyzed the translation of five words considered to be preferred by the author, as well as their co-text, in relation to three normalization features. The final results obtained in this study show that the translator Irene Matthews tends to use strategies that may be identified as features of normalization.

O estilo de João Ubaldo Ribeiro em Viva o Povo Brasileiros e An Invincible Memory

This paper aims at observing a particular case of an author’s and self-translator’s style in the pair of works Viva o Povo Brasileiro and An Invincible Memory. Our investigation has its theoretical starting point based on Corpus-Based Translation Studies (Baker, 1993, 1995, 1996, 2000; Camargo, 2005, 2007), and works on cultural domains (Nida, 1945; Aubert, 1981, 2006). The results showed that great part of cultural marks may be classified as the material, social, and ideological cultural domains, which reflects the context of the source text. It was also possible to observe that normalization features tends to reveal conscious or unconscious use of fluency strategies by the self-translator, making the translated text easier to read.

A tradução dos olhos em Clarice Lispector: uma investigação baseada em corpus

This investigation has as an objective to observe the translation of the word “eyes” and its collocates, in similar and (re)used fragments extracted from two books written by Clarice Lispector, A Descoberta do Mundo, translated by Giovanni Pontiero as Discovering the World and Uma Aprendizagem ou o Livro dos Prazeres, translated by Richard A. Mazzara and Lorri A. Parris as An Apprenticeship or The Book of Delights.Another objective is to identify aspects of normalization found in the respective translations of these fragments. The metodology is situated in the field of Corpus-based Translation Studies, (proposed by Baker, 1993, 1995, 1996, 1999, 2004; studies on normalization by de Scott, 1998); research and project by Camargo 2003a, 2003b, 2004, 2008), and in Corpus Linguistics (studies by Berber Sardinha, 2004); also, it is based on the author’s critical heritage (studies by Gotlib, 1993, 2009; Nunes, B., 1995; Sant‘Anna, 1997; Ruggero 2000; Sá, O., 2000; Franco Júnior, 2000; Ranzolin (1985), Varin, 2002; e Cherem, 2003). The results found in this research enabled to carry out a comparative study among the respective translators concerning tendencies to normalization and show Pontiero’s smaller tendency in relation to the couple of translators Richard A. Mazzara e Lorri A. Parris.

Avalição ecocardiográfica do ventrículo direito e da pressão arterial pulmonar em portadoresde hipertireoidismo

Pós-graduação em Fisiopatologia em Clínica Médica - FMB

Mudanças dento-esquelétics naturais e decorrentes do tratamento ortopédico da má oclusão de Classe II

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Despacho ótimo de potências ativa e reativa de sistema elétricos multi-áreas considerando restrições físicas, econômicas e ambientais =: Envronmentally constrained active-reactive optimal power flow-a compromising strategy for economic-emission dispatch and a multi-area paradigm

Pós-graduação em Engenharia Elétrica - FEIS

Determinação molecular da viabilidade do Mycobacterium leprae: uma comparação com outras abordagens metodológicas

Pós-graduação em Doenças Tropicais - FMB

Case study of children of referrals to health services: an individualizing design?

Nowadays education for all is recommended as an international action. However in Brazil one can observe homogeneous practices for a heterogeneous public. When the student has learning difficulties, there seems to be an attempt to normalization and pathologization by the means of referral, many times being indiscriminate, to health services. This case study aimed to analyze records of pedagogical strategies to meet the students educational needs before sending them to health services. Two records sent to a multidisciplinary team of a Regional Specialty Clinic (ARE) in a city of the state of São Paulo/Brazil, were used. The results reflect that the records of the educators do not show the pedagogical strategies used with the students and that the education system still seeks homogeneous classes, devaluating the diversity present in its context.

Análise do método suvrel na expressão diferencial a partir da matriz de contagens gerada com dados de RNA-SEQ

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Influência da adição do nióbio no comportamento mecânico e microestrutural do aço SAE 6150

Pós-graduação em Engenharia Mecânica - FEG