Luteal changes after treatment with sub-luteolytic doses of prostaglandin (cloprostenol sodium) in cattle

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

The effects of high doses of nandrolone decanoate and exercise on prostate microvasculature of adult and older rats

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Effects of different doses of sodium monensin on feeding behaviour, dry matter intake variation and selective consumption of feedlot Nellore cattle

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Absence of effects on the rat sperm quality after subacute exposure to low doses of fungicide prochloraz

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Características morfogênicas e estruturais da Brachiaria brizantha cv. Marandu submetida a diferentes doses de nitrogênio e alturas de resíduos

The objective of this study was to evaluate the rate of leaf appearance, leaf elongation rate, number of green leaves, length of blade and stem of Brachiaria brizantha cv. Marandu under different nitrogen levels and two residue heights. A randomized block design was used in a 4 x 2 factorial scheme, four doses of nitrogen (100, 200, 300 and 400 kg N ha(-1) year(-1)) and two residue heights (5 and 15 cm). There was significant interaction between residue height and nitrogen levels for leaf appearance rate of signal grass, which was influenced negatively and linearly by the residue heights being observed an average reduction of 28.20% from lower to higher residue. There was no interaction between the levels of nitrogen x residue height on the number of green leaves. The dosage that provided the highest stalk in the residue height of 5 cm was of 271.5 kg N ha(-1). An increase of 0.0745 cm tiller(-1) day(-1) for 1 kg of N ha(-1) applied to height of 15 cm of residue was observed. Nitrogen fertilization contributes positively to growth and development of rates of appearance and leaf extension. The management of pasture of Brachiaria brizantha cv. Marandu with 5 cm of residue and fertilization with 100 kg N ha(-1) provided better answer morphogenic traits.

Pharmacokinetics of flavanone glycosides after ingestion of single doses of fresh-squeezed orange juice versus commercially processed orange juice in healthy humans

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

The effect of non-antihypertensive doses of angiotensin converting enzyme inhibitor on myocardial necrosis and hypertrophy in young rats with renovascular hypertension

In renovascular hypertensive rats, low doses of angiotensin converting enzyme (ACE) inhibitors have been found to prevent myocardial hypertrophy independent of blood pressure level. This finding would suggest humoral rather than mechanical control of myocyte growth. The aim of this study was to examine the effect of nonantihypertensive doses of ACE inhibitor on myocardial hypertrophy and necrosis in hypertensive rats. Renovascular hypertension (RHT) was induced in four-week-old Wistar rats. Twenty-eight animals were treated for four weeks with three doses of ramipril (0.01, 0.1 or 1. 0 mg/kg/day, which are unable to lower blood pressure. Fourteen animals were not treated (RHT group). A sham operated, age/sex-matched group was used as control (n = 10). Myocardial histology was analysed in 3 microm thick sections of the ventricle stained with either haematoxylin-eosin, reticulin silver stain or Masson's trichrome. There was a significant correlation between systolic blood pressure and left ventricular to body weight ratio in both sets of animals: untreated plus controls and ramipril-treated rats. ACE inhibition prevented myocyte and perivascular necrosis and fibrosis in a dose-dependent manner. We conclude that myocardial hypertrophy in rats with renovascular hypertension is directly related to arterial pressure, and that this relationship is not affected by nonantihypertensive doses of ACE inhibitor. Myocardial necrosis/fibrosis and coronary artery damage induced by angiotensin II are prevented by ACE inhibitor in a dose-dependent manner, despite the presence of arterial hypertension.

Modulation of thyroid hormone receptors, TR alpha and TR beta, by using different doses of triiodothyronine (T3) at different times

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Hypocholesterolaemic effect of rat-administered oral doses of the isolated 7S globulins from cowpeas and adzuki beans

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Modulation of thyroid hormone receptors, TRα and TRβ, by using different doses of triiodothyronine (T3) at different times

Objective: To examine the effect of different doses of triiodothyronine (T3) on mRNA levels of thyroid hormone receptors, TRα and TRβ, at different times. Materials and methods: 3T3-L1 adipocytes were incubated with T3 (physiological dose: F; supraphysiological doses: SI or SII), or without T3 (control, C) for 0.5, 1, 6, or 24h. TRα and TRβ mRNA was detected using real-time polymerase chain reaction. Results: F increased TRβ mRNA levels at 0.5h. After 1h, TRα levels increased with F and SI and TRβ levels decreased with SII compared with C, F, and SI. After 6h, both genes were suppressed at all concentrations. In 24h, TRα and TRβ levels were similar to those of C group. Conclusions: T3 action with F began at 1h for TRα and at 0.5h for TRβ. These results suggest the importance of knowing the times and doses that activate T3 receptors in adipocytes.

Valor nutritivo do capim Piatã adubado com diferentes doses de biofertilizante

The aim of this study was to verify the influence of different doses of biofertilizers made from waste produced by cattle and pigs at growing-finishing on nutritive value of Piatã grass. The experiment was carried out at green house using a split plot design with a completely randomized factorial. Plots were divided into eight treatments: four doses of two biofertilizers, and four different periods of subplots cut. Biofertilizers were applied at a single dose, after the cut to standardize the plots, using doses of Nitrogen of 0, 100, 200 and 300 kg ha-1 . The results showed no significant difference among types of biofertilizer and also, the biofertilizer x dose interaction was not significant, making possible to recommend both of biofertilizers, with no risk of plant injure. Contents of neutral detergent fiber, acid detergent fiber, cellulose, hemicellulose and lignin showed negative linear behavior as a function of increasing doses of nitrogen. Contents of crude protein and “in vitro” dry matter digestibility coefficients replied linearly and positively to nitrogen doses. It also observed the effect of cut periods, since plants that were cut in summer showed nutritive value superior to those plants that were cut in autumn.

Effect of nitrogen and application ways of a plant biostimulant on different wheat genotypes contrasting in stature

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Efeitos de geada no desenvolvimento do feijoeiro em sucessão a espécies vegetais e adubação nitrogenada

O objetivo deste trabalho foi verificar o efeito de geada no desenvolvimento do feijoeiro em experimentação de cultivo em sucessão a espécies de cobertura e adubação nitrogenada, em delineamento experimental de blocos ao acaso em esquema de parcelas subdivididas, com quatro repetições. As parcelas foram constituídas pelas espécies Sorghum bicolor tipo guinea, Canavalia brasiliensis, Sorghum bicolor, Crotalaria juncea, Pennisetum glaucum e uma testemunha mantida no limpo, enquanto as subparcelas por doses de nitrogênio em cobertura (0, 25, 50 e 75 kg ha-1 de N), utilizando-se como fonte a uréia. Menores danos e severidade da geada foram constatados em plantas de feijão cultivadas após as espécies Canavalia brasiliensis e Crotalaria juncea, devido à menor quantidade de massa seca residual em relação à das culturas de gramíneas. Produtividades superiores de grãos de feijoeiro após geada foram obtidas na sucessão com Crotalária juncea e C. brasiliensis e com a aplicação de doses entre 44,5 e 52,0 kg ha-1 de N, em cobertura.

Produtividade e classificação de brócolos para indústria em função da adubação nitrogenada e potássica e dos espaçamentos entre plantas

No município de Itatiba-SP, no período de março a julho de 2007, foi realizado um experimento com o objetivo de avaliar doses de nitrogênio e potássio e espaçamentos entre plantas na produtividade e classificação de brócolos para indústria. O experimento foi instalado sob delineamento de blocos ao acaso, com os tratamentos em esquema fatorial 5 x 4, e três repetições, sendo avaliadas as doses de nitrogênio-potássio: 105-105; 157,5-157,5; 210-210; 262,5-262,5 e 315-315 kg ha-1 de N e K2O e os espaçamentos entre plantas: 0,2; 0,3; 0,4 e 0,5 m. O espaçamento entre linhas foi de 0,8 m. Foram avaliados o teor foliar de nitrogênio (TN) e de potássio (TP), produtividade de inflorescência (PI), produtividade de floretes (PF), rendimento industrial (RI) e classificação dos floretes com base em seu comprimento: PF5 (<5 cm); PF57 (>5 e <7 cm); PF79 (>7 e <9 cm) e PF9 (>9 cm). Maiores espaçamentos entre plantas proporcionaram maior TN e menores PI e PF. As doses NK e os espaçamentos entre plantas não influenciaram significativamente o TP e o RI. As maiores produtividades de inflorescências (22,08 t ha-1) e de floretes (17,09 t ha-1) foram obtidas com 0,20 m entre plantas e 315 kg ha-1 de N e de K2O. Maior percentagem de floretes na classe PF5 foi obtida no menor espaçamento entre plantas. As doses NK e os espaçamentos entre plantas não influenciaram as percentagens de floretes nas classes PF79 e PF9.

Adubação com nitrogênio e potássio em mudas de goiabeira em viveiro comercial

The fertilization takes key role at the production of fruit seedlings in order to ensure a good development and early production. The aim of this study was to evaluate the effects of nitrogen and potassium on the growth of guava seedlings. Herbaceous stakes of guava, Paluma cultivar, were rooted in a mist room, in polyethylene bags containing substrate. The experiment was conducted in a commercial nursery, in randomized blocks and a factorial scheme 4x4, with four doses of nitrogen (0, 552, 828 and 1104 mg dm(-3)) and four doses of potassium (0, 726, 1,089 and 1,452 mg dm(-3)) in three replications and three plants for parcel. During the filling of the bags (1,5 dm(-3)), were added 100 mg dm(-3) of superphosphate, while fertilizers containing nitrogen and potassium were split into three times. After 120 days, the seedlings were evaluated. There was a significant effect of nitrogen in the variables height, stem diameter, number of leaves, SPAD index, dry weight of leaves, stems, total, Dickson quality index, and nitrogen accumulation. The fertilization with potassium did not influence the biometric parameters, SPAD index and Dickson quality index.