110 resultados para 624.059
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Statement of problem. Removable partial dentures are affected by fatigue because of the cyclic mechanism of the masticatory system ansi frequent insertion and removal. Titanium and its alloys have been used in the manufacture of denture frameworks; however, preventive agents with fluorides are thought to attack titanium alloy surfaces.Purpose. This study evaluated, compared, analyzed the corrosion-fatigue life of commercially pure titanium and Ti-6Al-4V alloy in different storage environments.Material and methods. For each metal, 33 dumbbell rods, 2.3 mm in diameter at the central segment, were cast in the Rematitan system. Corrosion-fatigue strength test was carried out through a universal testing machine with a load 30% lon er than the 0.2% offset yield strength and a combined influence of different: environments: in air at room temperature, with synthetic saliva, and with fluoride synthetic saliva. After failure, the number of cycles were recorded, and fracture surfaces were examined with on SEM.Results. ANOVA and Tukey's multiple comparison rest indicated that Ti-6Al-4V alloy achieved 21,269 cycles (SD = 8,355) against 19,157 cycles (SD = 3,624) for the commercially purr Ti. There were no significant differences between either metal in the corrosion-fatigue life for dry specimens, but when the solutions were present, the fatigue life was significantly reduced, probably because of the product-ion of corrosion pits caused by superficial reactions.
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Vitamin A is important to the proper development and functioning of the body, appearing in several metabolic functions. This experiment was conducted with aim evaluate to the vitamin A supplementation in diets for Goldfish Carassius auratus. The experimental was completely randomized with six treatments (0, 2.000, 4.000, 8.000, 16.000 and 32.000 IU of vitamin A kg(-1) diet) with four repetitions into 24 experimental cages, with capacity for 150 liters useful volume, made of mesh shading, installed inside a masonry circular tank with a capacity of 25 m(3) of water. 192 fish with an average initial weight of 6.66 +/- 0.57 g and initial length of 7.30 +/- 0.33 cm, feed at 8h, 11h, 14h and 17h at satiety were used. Evaluated the effects on productive performance and intensity of yellow-red coloring of the skin of the fish were. The Linear Response Plateau analysis of weight gain and length total, feed conversion and daily growth rate versus vitamin A requirement estimate showed 2,624, 2,385 and 2,358, 4,381 and 2,866 IU of vitamin A per kg diet, respectively. The data indicated that this vitamin has little or no influence on the intensity of the skin color of the Goldfish.
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O objetivo deste estudo foi avaliar o desempenho dos sistemas sensoriais e do controle postural de idosos diabéticos e investigar a relação entre as alterações destes sistemas e do controle postural desta população. Participaram deste estudo dez idosos diabéticos ativos (62±4,4 anos) (GDA), 10 diabéticos sedentários (65,5±7,4 anos) (GDS) e 10 idosos saudáveis ativos (63,2±4.5anos) (GCA) foram submetidos a avaliações sensoriais e de controle postural. As avaliações sensoriais foram compostas por avaliação somatossensorial (sensibilidade cutânea e sensibilidade ao movimento passivo). Para avaliar o controle postural foram analisadas medidas de oscilação corporal durante manutenção da postura ereta (em tandem stance e bipodal). Os resultados indicaram pior desempenho do GDS na avaliação do movimento passivo e de controle postural. Nas avaliações de controle postural, o GDS apresentou uma maior amplitude média de oscilação (AMO) (cm) nas condições de manutenção da postura ereta na posição tandem stance na direção médio-lateral. No teste de sensibilidade ao movimento passivo, o GDS precisou, em média, de um maior deslocamento angular para perceber o movimento das articulações do joelho e tornozelo. Estes resultados indicam, portanto, que as alterações estruturais e fisiológicas decorrentes do diabetes, resultam em piora do desempenho dos sistemas sensoriais e de controle postural. Além disso, a maior deterioração do sistema proprioceptivo em idosos diabéticos pode interferir negativamente no desempenho de controle postural dos mesmos. Desta forma, a atividade física minimiza a perda sensorial e ainda ajuda no controle postural dos diabéticos.
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Early detection assays play a key role in the successful treatment of most diseases. Redox capacitive biosensors were recently introduced as a potential electroanalytical assay platform for point-of-care applications but alternative surfaces (besides a mixed layer containing ferrocene and antibody receptive component) for recruiting important clinical biomarkers are still needed. Aiming to develop alternative receptive surfaces for this novel electrochemical biosensing platform, we synthesized a ferrocene redoxtagged peptide capable of self-assembly into metallic interfaces, a potentially useful biological surface functionalization for bedside diagnostic assays. As a proof of concept we used C-reactive protein (CRP), as a model biomarker, and compared the obtained results to those of previously reported capacitive assays. The redox-tagged peptide approach shows a limit of detection of 0.8 nmol L 1 (same as 94 ng mL 1 ) and a linear range (R2 ∼98%) with the logarithm of the concentration of the analyte comprising 0.5–10.0 nmol L 1 , within a clinical relevant range for CRP.
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)