Resposta celular imune-inflamatória e de células caliciformes no intestino delgado de bezerros búfalos naturalmente infectados por Toxocara vitulorum

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Afonso Lomonaco: a visão de um viajante europeu sobre o Brasil do final do século XIX

O presente artigo trata das visões deixadas a respeito do Brasil pelo viajante italiano Affonso Lomonaco em seu livro Al Brazile. Mostro, que,como seu roteiro de viagem restringiuse somente aos locais aonde a ferrovia chegava, seus relatos a respeito da sociedade brasileira ficaram circunscritos ao que viu nos ambientes urbanos. Também pelo fato de ser europeu de origem citadina, suas impressões aparecem profundamente marcadas por valores burgueses e racistas.

Interações entre diferentes espécies de Candida na candidose experimental em modelos de invertebrados e vertebrados

Pós-graduação em Biopatologia Bucal - ICT

Variação sazonal no recrutamento de Phragmatopoma caudata (Polychaeta, Sabellariidae) na costa sudeste do Brasil: biometria e validação de metodologia para categorização de classes etárias

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Detecção e localização de danos em materiais compósitos aplicado em aeronaves utilizando redes neurais artificiais

Pós-graduação em Engenharia Mecânica - FEIS

EFFECT OF Bifidobacterium animalis ON MICE INFECTED WITH Strongyloides venezuelensis

The administration of viable Bifidobacterium animalis was tested to induce resistance against Strongyloides venezuelensis infection in mice. Effects on parasite burden, worm length, egg output, and intestinal mucosal histology were evaluated. The oral administration of B. animalis, strain 04450B, starting 14 days before the inoculation of nematode larvae significantly decreased the worm burden and egg output. In probiotic treated animals, the percent reduction of adult worms in the intestine was of 33% and the reduction of egg production was of 21%, compared with those of the control group. The duodenum villous height and villous/crypt ratio were significantly higher in probiotic-treated mice, indicating that this group could be experiencing less intestinal damage. The present findings revealed that the administration of B. animalis for the amelioration of host response to nematode infections is biologically plausible and could have some potential for impacting public health. Meanwhile, further study is needed to delineate the nature and identity of the factor(s) involved in these beneficial effects.

Immunological and parasitological parameters in Schistosoma mansoni-infected mice treated with crude extract from the leaves of Mentha x piperita L.

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Vilas ferroviárias em Bauru: a essência de uma cidade

A pesquisa propõe-se a listar, relacionar e analisar a partir de documentos, manuscritos e relatos orais, de que forma se constituíram os meios e modos de habitação das vilas ferroviárias em Bauru até meados do século XX. Como a ferrovia trouxe consigo uma infra-estrutura necessária ao seu funcionamento, busca-se estabelecer as relações entre a chegada da ferrovia e a cidade de Bauru, e de que forma essa estrutura interferiu na lógica urbanizadora. Assim, pretende-se resgatar a memória da cidade de Bauru relacionando-a a chegada da ferrovia, através do período que compreende os primeiros cinqüenta anos do século vinte abrangendo a chegada dos três ramais ferroviários que serviram à cidade, sua ascensão (fase na qual encontram-se a maioria dos edifícios estudados) e o seu declínio. Para ser implantada em uma cidade, a ferrovia precisava ter uma infra-estrutura básica, necessária ao seu funcionamento, como os armazéns, as estações, as oficinas, os pátios, inclusive as moradias construídas para os funcionários. Esse conjunto é denominado “complexo ferroviário”. Durante o presente trabalho, tem por objetivo aprofundar-se nos estudos das residências construídas pelas companhias ferroviárias. Segundo Eva Blay, vila é o conjunto de casas construídas no interior de um terreno. Mas será que todas as vilas construídas pela mesma Companhia ferroviária possuem o mesmo padrão arquitetônico? Ou o mesmo padrão de loteamento? Como era a arquitetura das casas nas vilas? Através de pesquisas, procuramos responder a esses e outros questionamentos. Como estão hoje as vilas? Quem são seus moradores?Aconteceram alterações na arquitetura das vilas?

Atividade imunomoduladora de parasporina de Bacillus thuringiensis sobre linfócitos e monócitos humanos

Bacillus thuringiensis is an environmental bacteria that produces a group of crystallizable proteins (Cry) that are toxic for several insects and worms species. Recently, it was described a novel class of Cry proteins called parasporins (PS) that showed cytotoxic effects on animal and human tumor cells. Six types of PS have been described so far, PS1 to PS6, and their cytotoxic activity has been studied. However, the direct effect on tumor cells has been the current research focus, while the immunomodulatory role of the PS has not been studied yet. Therefore, this study aimed to verify whether PS of TC 2.3.1R6 B. thuringiensis strain has immunostimulatory activity on human lymphocytes and monocytes. We have evaluated the protein toxicity against human cells, the lymphoproliferative activity and the effects on peripheral blood monocytes. The PS-PK showed no toxic or stimulating activity on lymphocyte proliferation. However, it inhibited the spontaneous production of IL-10 as well as ConA-induced and the production of IFN-γ. PS-PK decreased the release of hydrogen peroxide and increased the production of TNF- α by monocytes. PS-PK performed inhibitory production of hydrogen peroxide and TNF-α by monocytes, whereas PS-Tp showed stimulation of the production of hydrogen and TNF-α

Caracterização da resistência à ivermectina de um isolado de Haemonchus contortus em ovinos: se tiver subtitulo

The production of sheep, both in Brazil and worldwide, has shown significant growth in the last years but still has some obstacles to its development, among them are the low indexes caused by parasites, with emphasis on haemoncose. Among the control methods used in the fight against worms are the anthelmintics, and one of the most active principles in this traditional treatment is ivermectin. While being the tool of choice in the treatment of parasitic diseases, improper use of the same led to the emergence of resistant isolates, not only to ivermectin, as several other active principles of antiparasitic drugs

Análise do conforto térmico da cidade de Mirandópolis/SP em seus espaços abertos

Mirandópolis/SP appeared in 1934 from the railroad “the Brazil Northwest”, that there it served one of the points of its stretch that had as main function to drain the agricultural production northwestern native of São Paulo of that time. The installation of the town happened absent of concerns with initial urbanístico planning, thus modifying its natural landscape and modifying characteristic ambient without compensatory measures aiming at a future expansion of the urban mesh. Fact this that still causes today consequences the quality of life of the people and also the observed thermal comfort later. Ahead of this, the present work had for objective to identify through measurements of temperature and relative humidity of the city of Mirandópolis/SP the differences that in the fabric urban they corroborate for a comfort situation or thermal discomfort to the outdoors in accordance with the Diagram Bioclimático de Olgyay the collection of data was made throughout the month of July of 2011 involving the attainment of information of Temperature and relative humidity of air and questionnaire applied to the passer-bys in the act of the measurements. Also approaching the different thermal dynamic of the zones of housing in relation to the Urban Cannyon that develops the commerce as predominant activity. This research sample that, although a city to be small, the quality of life of its inhabitants is not only guaranteed by the transport or that its thermal comfort reveals inside homogeneous of the urban perimeter, but that it has yes heterogeneidade in the scope of the urban climate in these spaces

Grãos em carbonatos marinhos cretácicos da Bacia Potiguar: formações Ponta do Mel e Jandaíra

This work aims to identify and photograph grains that compose important Cretaceous carbonate units of the Potiguar Basin, represented by the Ponta do Mel and Jandaíra formations (Albian-Campanian). Petrographic investigation of thin sections was essential. The samples studied come from wells and surface samples from the collection UNESPetro – UNESP, Rio Claro. In the Ponta do Mel Formation, the grains consist of ooids, oncoids, peloids and bioclasts. Regarding to the identified bioclasts, the solenoporacean red algae, mollusks (bivalves and gastropods), echinoids, foraminifera, ostracods and worms were the dominant elements. In the Jandaíra Formation, the grains are composed by ooids, peloids and bioclasts, which are represented by green algae, mollusks (bivalves and gastropods), benthic foraminifera miliolids, worms, echinoderms and ostracods. The grains found in the Ponta do Mel Formation are somewhat similar to those found in the Jandaíra Formation, with the exception of calcareous algae. The subsurface material from the Ponta do Mel Formation is derived from the upper part of the unit, representing marine high-energy carbonates, which also contains ooids and Trocholina. The samples of Jandaíra Formation, collected in outcrops, often contain green algae, mollusks and miliolids, and come from inner shelf and lagoon facies previously described

Conexão cultura: um projeto de revitalização e reestruturação da estação ferroviária de Guaratinguetá

This work presents an intervention at the Guaratinguetá Railway Station and its surroundings, including this area in the urban context, at this moment isolated of the activities and citizen attentions, offering new activities on this commercial area. The selected area finds itself in a state of neglect and forgetfulness from the urban relations. Located between the periphery of the commercial center and the Paraiba do Sul River, the correlation is tension between the advancement of shops, the railway line, and the natural barrier of the Paraiba River. On the context of these limits, the railroad and the river stand as barriers for the center expansion and the flows that connect the old part of the town with the new part, which is growing and is called “post-city river”. These barriers have relegating properties around them to isolation, despite being located in the center. The area choice and this intervention seeks to break this isolation and the barrier flow, linking areas of opposite sides to form a leak through the barrier of the railway line. The pedestrian flow is prioritized in the project, this flow will be attracted by the program offered and by the new created areas, increasing the space utilization by users and breaking the isolation of urban activities. And entering the area in the context of life of city residents. The attraction of these new flows will be through the implementation of a Cultural Center, supplying a lack of city by spaces that offer this type of activity. Its implementation aims to attract and modify the activities of these spaces and the surrounding areas, one side facing the commercial center, and another facing the river, linking this two sides at the same time that this link provides the expansion of distance traveled and known

Phytotherapy in the control of helminthiasis in production animals

Parasitic diseases constitute one of the main problems affecting livestock; however the use of chemical medicaments provides drug resistance residues in animal and environmental contamination. Changes in production concepts require that food must be produced in hygienic conditions, per healthy animals and that are not eliminating antibiotic residues, pesticides or other drugs. This scenario has favored organic production and the use of medicinal plants. For the control of endoparasites, several studies have published the benefits of Azadirachta indica A. Juss., Punica granatum Linn., Musa sp., Operculina hamiltonii G. DON., propolis, among others. However, despite the existence in- vitro studies that demonstrate the pharmacological properties of phytotherapics, there is still need for clinical trials to determine dosage and its effects in- vivo. Investigations of new bioactive natural substances can be of great value for the control of animal health and food safety, which is particularly important for organic production systems in which the use of chemical drugs is a limiting factor for certification.

Raia Divisória ou Raia Socioambiental?: uma redefinição baseada na análise da paisagem através do sistema GTP

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)