Avaliação dos efeitos ambientais nas propriedades do compósito de poliamida 6,6/fibras de carbono

This graduation work done study of polyamide 6.6/composite carbon fibres, since its processing, characterization of the main properties. Besides the influence of temperature, UV radiation, salt spray and moisture on the mechanical and viscoelastic behavior. To achieve this goal, the first composite was processed from the heat compression molding using known variables of the process and using the empirical method to find the best value for other parameters. The method processing molding was chosen because it common in composites processing in order to evaluate the influence of crystallinity of the properties that influence the mechanical and viscoelastic behavior laminates. From the obtained laminate specimens were evaluated in weathering, such as: in hygrothermal chamber, UV, salt spray and thermal shock. In another step, the effect produced by these constraints were evaluated by optical microscopy, ultrasound, dynamic mechanical analysis and vibration tests. This project was conducted at the Department of Technology and Materials of UNESP in Guaratingueta, where all the equipment and techniques for the implementation of this project met available. After the tests proved the applicability of the composite polyamide 6.6/carbon fibers in aeronautical applications with resistance the main climatic influences

Effects of dipyrone, meloxicam, or the combination on hemostasis in conscious dogs

To compare the effects of dipyrone, meloxicam, and of the combination of these drugs on hemostasis in dogs. Prospective, blinded, randomized crossover study. Research laboratory at a veterinary teaching hospital. Six adult dogs. Animals received 4 intravenous treatments with 15-day washout intervals: control (physiological saline, 0.1 mL/kg), meloxicam (0.2 mg/kg), dipyrone (25 mg/kg), and dipyrone-meloxicam (25 and 0.2 mg/kg, respectively). A jugular catheter was placed for drug injection and for collecting samples for whole blood platelet aggregation (WBPA) and thromboelastometry assays at baseline, 1, 2, 3, 5, and 8 hours after treatment administration. The percent change from baseline of lag time and of the area under the curve (AUC) of impedance changes in response to collagen-induced platelet activation were recorded during WBPA. Thromboelastometry-derived parameters included clotting time, clot formation time, alpha-angle, and maximum clot firmness. The buccal mucosal bleeding time was evaluated by a blinded observer at baseline, 1, 3, and 5 hours after treatment injection. No significant changes in WBPA and thromboelastometry were recorded in the control treatment. Dipyrone significantly (P < 0.05) increased the lag time for 2 hours and decreased the AUC for 3 hours after injection. Meloxicam did not alter WBPA. Dipyrone-meloxicam significantly increased lag time for 2 hours and decreased the AUC for 5 hours after treatment injection. Experimental treatments did not differ from the control treatment for thromboelastometry and buccal mucosal bleeding time. While meloxicam does not alter hemostasis by the methods evaluated, dipyrone inhibits platelet aggregation for up to 3 hours. Meloxicam-dipyrone combination causes more prolonged inhibition of platelet function than dipyrone alone. Decreased platelet aggregation induced by dipyrone and dipyrone-meloxicam does not appear to impact the viscoelastic properties of the blood clot nor increase the risk of bleeding in dogs without preexisting hemostatic disorders.

Estudos teóricos e numéricos de escoamentos com escorregamento

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Análise dinâmica em vigas compostas com amortecimento utilizando o método dos elementos espectrais e elementos finitos

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Predição de vida em fadiga de compósitos estruturais baseado em análises dinâmico-mecânicas

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Rheological characterisation and effect of abiotic factors on the antimicrobial efficacy of chitosan-based hidrogels containing alpha-hydroxy acids

The aim of this study was to investigate the rheological properties and antibacterial efficacy of chitosan/ alpha-hydroxy acids (lactic acid and glycolic acid) and cellulose polymers, both in hydrogels, in order to produce a formulation with improved activity against Propionibacterium acnes and Staphylococcus aureus, which can potentially be used in the treatment of acne. The rheological characterisation of the hydrogels was examined using continuous shear and viscoelastic creep. The antibacterial activities of formulations were performed by the well diffusion and broth microdilution. The hydrogels formulated with only chitosan showed pseudoplastic behavior while the chitosan hydrogels with cellulose polymers presented viscoelastic properties. The antibacterial activity was proportional to AHA and chitosan concentration. It was enhanced at low pH values and with high molecular weight chitosan and did not change with the incorporation of two cellulose polymers. The antibacterial mechanism of chitosan has currently been hypothesized as being related to surface interference. The results show that chitosan - based hydrogels containing AHA and cellulose polymers are viscoelastic,indicating good applicability onto the skin, and they present bacterial activity under various experimental conditions.