Elementos de transposição como fonte de novidades genéticas em nível transcricional: uma abordagem computacional e molecular

Pós-graduação em Genética - IBILCE

Effect of a polysaccharidic fraction of Agaricus blazei on colorectal carcinogenesis in rats with ulcerative colitis

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

4th Symposium of Immunology: Tumor Immunobiology

This Abstract book includes all Abstracts of presentations at the 4th Symposion of Immunology: Tumor Immunology, which occurred in the São Paulo State University - UNESP, Bioscience Institute, Botucatu, SP, Brazil, from May 20-22nd, 2011.

Uma introdução à filosofia das ciências da vida e da saúde

O interesse de estudantes, pesquisadores e profissionais das ciências da vida e da saúde pela Filosofia da Ciência e a dificuldade que eles enfrentam para obter fundamentos teóricos diretamente de obras filosóficas motivaram a produção desse livro. Para os autores, a Filosofia da Ciência contribui para a formação de pesquisadores à medida que os princípios básicos da pesquisa científica e de seu significado contribuem para a produção de novos conhecimentos. Eles afirmam que o método científico se constitui na ferramenta adequada para a construção de soluções eficazes para problemas que profissionais e pesquisadores encontrarão ao longo se suas atividades, já que os capacita a fazer análises, sínteses e críticas baseadas no raciocínio científico. Outra importante colaboração é fornecer uma perspectiva do processo histórico da ciência. Ao longo dos capítulos são abordados temas como a natureza do conhecimento científico e o modo de produção da ciência. Os autores ainda apresentam uma breve história do pensamento biológico, além de conceitos e métodos das teorias Geral dos Sistemas e da Auto-organização, fundamentais para a tipificação dos fenômenos biológicos e para uma concepção da natureza como resultante da interação dinâmica entre fatores biológicos, psicológicos e sociais. Eles também abordam a relação entre a atividade científica e a sociedade tecnológica atual, inclusive discutindo sobre a ética que deve reger esse relacionamento. A obra faz um foco ainda sobre a psicossomática, que analisa por diversos aspectos: expõe seus fundamentos teóricos, bases fisiológicas e hipóteses filosóficas em torno do problema mente-corpo desenvolvidas ao longo da história, além de avaliar os mecanismos fisiológicos próprios aos processos psicossomáticos e demonstrar de que modo a psicossomática poderia ser aplicada à saúde coletiva.

Prevalence and phenotypic characterization of Enterococcus spp. isolated from food in Brazil

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Montagem de um conjunto experimental destinado à verificação do princípio da incerteza de Heisenberg

In this paper we present the an experimental setup to check the Heisenberg uncertainty principle. The description of the experimental setup and of the theoretical foundations is aimed at promoting the familiarization of the students with the involved concepts.

Energy Management and Control for Islanded Microgrid Using Multi-Agents

This paper presents a multi-agent system for real-time operation of simulated microgrid using the Smart-Grid Test Bed at Washington State University. The multi-agent system (MAS) was developed in JADE (Java Agent DEvelopment Framework) which is a Foundation for Intelligent Physical Agents (FIPA) compliant open source multi-agent platform. The proposed operational strategy is mainly focused on using an appropriate energy management and control strategies to improve the operation of an islanded microgrid, formed by photovoltaic (PV) solar energy, batteries and resistive and rotating machines loads. The focus is on resource management and to avoid impact on loads from abrupt variations or interruption that changes the operating conditions. The management and control of the PV system is performed in JADE, while the microgrid model is simulated in RSCAD/RTDS (Real-Time Digital Simulator). Finally, the outcome of simulation studies demonstrated the feasibility of the proposed multi-agent approach for real-time operation of a microgrid.

Natural Products from Cyanobacteria with Antimicrobial and Antitumor Activity

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Ability of Salmonella spp. to Produce Biofilm Is Dependent on Temperature and Surface Material

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Performance and emissions of a gas turbine engine using ox tallow ethyl-ester blended with kerosene

The performance and emissions behavior of a Rover 1S/60 turboshaft engine when operated with several blends of aviation kerosene and ox tallow ethyl-ester are shown in this article. The tests were performed with a compressor shaft coupled to an hydraulic dynamometer where data of power and mass fuel flow were collected to determine the brake specific fuel consumption. A flue gas analyzer was positioned at the exhaust duct to collect oxygen, carbon dioxide, carbon monoxide and nitrous oxides. An increase in the specific fuel consumption was observed due to the lesser lower heating value of the most oxygenated blends. However, reductions of CO, CO2 and NO (x) have been observed and no-significant ill effects have occurred in the turbine operation.

Allometric growth of non-carcass components in crossed lambs

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Bothropoides insularis venom cytotoxicity in renal tubular epithelia cells

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

THE RETINAL TARGETS OF CENTRIFUGAL NEURONS AND THE RETINAL NEURONS PROJECTING TO THE ACCESSORY OPTIC-SYSTEM

In birds, neurons of the isthmo-optic nucleus (ION), as well as ''ectopic'' neurons, send axons to the retina, where they synapse on cells in the inner nuclear layer (INL). Previous work has shown that centrifugal axons can be divided into two anatomically distinct types depending on their mode of termination: either ''convergent'' or ''divergent'' (Ramon y Cajal, 1889; Maturana and Frenk, 1965). We show that cytochrome-oxidase histochemistry specifically labels ''convergent'' centrifugal axons and target neurons which appear to be amacrine cells, as well as three ''types'' of ganglion cells: two types found in the INL (displaced ganglion cells) and one in the ganglion cell layer. Labeled target amacrine cells have distinct darkly labeled ''nests'' of boutons enveloping the somas, are associated with labeled centrifugal fibers, and are confined to central retina. Lesions of the isthmo-optic tract abolish the cytochrome-oxidase labeling in the centrifugal axons and in the target amacrine cells but not in the ganglion cells. Cytochromeoxidase-labeled ganglion cells in the INL are large; one type is oval and similar to the classical displaced ganglion cells of Dogiel, which have been reported to receive centrifugal input; the other type is rounder. Rhodamine beads injected into the accessory optic system results in retrograde label in both types of cells, showing that two distinct types of displaced ganglion cells project to the accessory optic system in chickens. The ganglion cells in the ganglion cell layer that label for cytochrome oxidase also project to the accessory optic system. These have proximal dendrites that ramify in the outer inner plexiform layer. Neither the target amacrine cells nor either of the displaced ganglion cells are immunoreactive for the inhibitory transmitter gamma aminobutyric acid. At least some of the target amacrine cells may, however, be cholinoceptive: we found that the antibody to the alpha-7 subunit of the nicotinic ACh receptor labels a population of cells in the INL that are similar in location, size, and the presence of labeled bouton-like structures to those we find labeled with cytochrome oxidase. This antibody also labels neurons in the ION proper but not ectopic cells. In conclusion, it appears that cytochrome oxidase may be a marker for ''convergent'' centrifugal axons and at least one of their target cells in the INL.

Produção de enzimas ligninolíticas, glioxal oxidase e proteases por fungos marinhos

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Mapeamento da ilha da Trindade, Atlântico Sul

The area chosen for this study is the island of Trinidade, which is located 1167 km off the Brazilian coast, in parallel Victory at 20 ° 30'S and 29 º 19'W, being the most easterly point of our continent. The isolation of oceanic island of Trinidade leaves no noticeable that she is part of a large submarine volcanic chain oriented east-west lineament known as Vitória- Trindade. Along with the island of Martin Vaz, who is Federal Territory is administered by the Navy of Brazil. Both correspond to Source alkaline volcanic islands. The area of the island of Trinidad has approximately 10 km2. Geologically consisting ankaratritic spills, spills tannbuschiticos, volcanic tuff spills analcite-ankaratrite, phonolite spills, spills nefelinite, pyroclastics, spills grazinite, tinguaitos, olivine-analcitito, calcarenite dunes and wind according to Almeida (1961). The island has its base on the ocean floor, at 5,800 m depth. It is the only place still recognizes preserved volcanic necks and plugs, as well as remnants of a volcano in Brazil. Magmatism occurred here a sodium alkali-silica subsaturated where his wrist was last 50,000 years according to Almeida (1961). It is a place with restricted access due to their distance from the coast, his contribution and hard to be an exclusive area of the Navy. On the island with peaks occur up to 620 meters high, and its rugged mountainous terrain and difficult access to very specific points, as the peak of Desire, peak Fazendinha, Monument and other points on the island. Because of its location far from the coast, its small infrastructure, difficulty of landing and restricted access by sea, the island of Trinidad offers no possibility of tourism, being a military outpost, and scientific basis of great importance, which conduct research in area of marine biology, oceanography, geology and others