106 resultados para Genome Scan


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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Pós-graduação em Ciência da Informação - FFC

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The research presents as its central theme the study of the bibliographic record conversion process. The object of study is framed by an understanding of analogic bibliographic record conversion to the Bibliograhpic MARC21 format, based on a syntactic and semantic analysis of records described according to descriptive metadata structure standards and content standards. The objective of this research the objective is to develop a theoretical-conceptual model of syntactic and semantic of bibliographic records, from Linguistic studies of Saussure and Hjelmslev of manifestations of human language, which subsidizes the development of a computacional interpreter, focused to the conversion of bibliographic records to MARC21 Bibliographic Format, which can be confirmed both the semantic value of the informational resource represented as the reliability of the representation. Given the aforementioned objectives, the methodological trajectory of the research is based on the qualitative approach, of an exploratory, descriptive and experimental nature, and with recourse to the literature. Contributions on the theoretical plane can be envisaged regarding the development of questions inherent to the syntactic and semantic aspects of bibliographic records, and by involving, at the same time, interdisciplinarity between Information Science, Computer Science and Linguistics. Contributions to the practical field are identified by the fact the study covers the development of the Scan for MARC, a computational interpreter that can be adopted by any institution that wishes to use the conversion procedure for bibliographic record databases to the MARC21 Bibliographic Format from description and visualization schemes of bibliographic records (AACR2r and ISBD), an aspect of the research which is considered innovative.

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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The length of the post-partum anoestrous interval affects reproductive efficiency in many tropical beef cattle herds. In this study, results from genome-wide association studies (Experiment 1: GWAS) and gene expression (Experiment 2: microarray) were combined in a systems approach to reveal genetic markers, genes and pathways underlying the physiology of post-partum anoestrus in tropically adapted cattle. The microarray study measured the expression of 13,964 genes in the hypothalamus of Brahman cows. A total of 366 genes were differentially expressed (DE) in the post-partum period, when acyclic cows were compared to cows that had resumed ovarian cycles. Associated markers (P < 0.05) from a high density GWAS pointed to 2829 genes that were associated with post-partum anoestrous interval (PPAI) in two populations of beef cattle: Brahman and Tropical composite. Together the experiments provided evidence for 63 genes that are likely to influence the resumption of ovulation post-partum in tropically adapted beef cattle. Functional annotation analysis revealed that some of the 63 genes have known roles in hormonal activity, energy balance and neuronal synapse plasticity. Polymorphisms within candidate genes identified by this systems approach could have biological significance in post-partum anoestrus and help select Zebu (Bos indicus) influenced cattle with genetic potential for shorter post-partum anoestrus. Crown Copyright (C) 2014 Published by Elsevier B.V. All rights reserved.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Pós-graduação em Genética e Melhoramento Animal - FCAV

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Dendrophylliidae is one of the few monophyletic families within the Scleractinia that embraces zooxanthellate and azooxanthellate species represented by both solitary and colonial forms. Among the exclusively azooxanthellate genera, Dendrophyllia is reported worldwide from 1 to 1200 m deep. To date, although three complete mitochondrial (mt) genomes from representatives of the family are available, only that from Turbinaria peltata has been formally published. Here we describe the complete nucleotide sequence of the mt genome from Dendrophyllia arbuscula that is 19 069 bp in length and comprises two rDNAs, two tRNAs, and 13 protein-coding genes arranged in the canonical scleractinian mt gene order. No genes overlap, resulting in the presence of 18 intergenic spacers and one of the longest scleractinian mt genome sequenced to date.

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Pós-graduação em Genética e Melhoramento Animal - FCAV

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)