Interdisciplinary approach to treat dyskeratosis congenita associated with severe aplastic anemia: A case report

This paper reports on a 4-year-old male who had dyskeratosis congenita and who acquired severe aplastic anemia. The patient developed hyperpigmentation of the face, neck and chest region, arms, shoulders and legs. In addition, he had dry skin, deformed fingernails and toenails, sparse hair and eyebrows and hyperkeratosis of the dorsum of the hands and feet. Laboratory and histological analysis revealed severe pancytopenia and dyserythropoiesis of red blood cells, hypocellularity of white blood cells and decreased megakaryocytes with dysplasia. The intraoral examination identified bleeding gums; petechiae of the palate, tongue and cheek mucosa; and an atrophic, smooth and shining dorsal surface of the tongue. There were deep carious lesions in the deciduous mandibular molars and maxillary anterior teeth; as well as mobility of mandibular left canine, which had bone loss. The treatment for oral lesions included diet changes, improved oral hygiene, and extraction of the deciduous teeth destroyed by caries.

Tratamento hepatoprotetor favorece a resposta leucocitária de ratos wistar intoxicados por CCL4

The aims of this investigation was to evaluate the effect of hepatoprotective treatments with a compound prepared by the association of N-Acetyl DL-Methionine (5%) + Choline chloride (2%) + Caffeine (1%) + Thiamine hydrochloride (1%) + Nicotinamida (0,5%)+ Pyridoxine hydrochloride (0.04%), administered through intramuscular (IM) route, at doses of 0.2, 0.6 and 1.0 mL/kg of BW, through the study of leukocytes responses in rats submitted to acute intoxication with CCl4. 147 females were randomized into 21 groups, performing five different treatments, which were evaluated seven animals in four periods: two, four, six and eight days after CCl4-induced intoxication. In this study, it was observed absolute eosinophilia and monocytosis in animals untreated and treated with the lowest dose of 0.2 mL. These responses were significantly better in animals treated with 0.6 and 1.0 mL/ kg BW. The untreated animals showed thrombocytopenia, when compared to treated animals. Absolute neutropenia and lymphocytosis was observed in all rats intoxicated with CCl4, there is no difference among treatments. The analysis of white blood cells demonstrated that the hepatoprotective treatments favored the leukocyte response, by act beneficially on the population of these cells, supporting the hypothesis that these events may reduce the deleterious effects in liver tissue after intoxication by CCl4.

Fungigação no controle do mofo branco e produtividade do feijoeiro em condições de cerrado brasileiro

The aim of this research was to evaluate the white mold severity (Sclerotinia sclerotiorum (Lib.) of Bary), bean production components and yield (Phaseolus vulgaris L.), variety Perola, according to the application of procimidone fungicide (Sialex 500), through fungigation (center pivot) and automotive sprayer (Uniport). The study was carried under field production commercial conditions, in Primavera do Leste - MT - Brazil. The experiment consisted of 5 treatments (with 4 repetitions of 4 ha each), all with two procimidone applications (1.2 kg ha-1 each application, same as, 0.6 kg a.i. per hectare) to the 42 and 52 days after seeding. The water depths of 5.5 and 11.0 mm were tested in the application through central pivot (this had your checked uniformity), providing volumes of 55.000 and 110.000 L ha-1, respectively, and the volumes of 120 and 200 L ha-1 in the automotive sprayer. The severity of disease was evaluated by the percentage of the area affected by plant damage using diagramatic grade scale of white mold severity, as described by Azevedo (1998). The values were used to calculate the area under the disease progress curve (AUDPC). They were also analyzed, the number of the fungus apothecia during the crop cycle and the residual sclerotias weight in harvest. On this occasion, it was also evaluated the crop yield parameters: number of plants per plot (final stand), pods per plant, grains per pod, medium weight of 200 grains and productivity of grains. The AUDPC values, apothecia to 42, 49 and 56 days after seeding, sclerotias in 2 soil kg and the crop productivity parameters were submitted to the variance analysis and Tukey Test at 0.05 of probability. This test was also applied in the comparison among the different fungicide application methods, independent of spray volumes in each one. The statistical processing was accomplished by STAT program. The results showed that weren't differences among application techniques studied in relation to productivity parameters, however, best white mold control, smaller apothecia number to 49 and 56 days after seeding and smaller weight of residual sclerotias in the harvest were obtained with the fungigation, independently of the spray volume used.

Optimizing optimum-path forest classification for huge datasets

Traditional pattern recognition techniques can not handle the classification of large datasets with both efficiency and effectiveness. In this context, the Optimum-Path Forest (OPF) classifier was recently introduced, trying to achieve high recognition rates and low computational cost. Although OPF was much faster than Support Vector Machines for training, it was slightly slower for classification. In this paper, we present the Efficient OPF (EOPF), which is an enhanced and faster version of the traditional OPF, and validate it for the automatic recognition of white matter and gray matter in magnetic resonance images of the human brain. © 2010 IEEE.

Notas sobre a nidificação de aves brasileiras raras e/ou pouco conhecidas

We describe the nests and nesting behaviour of six little-known birds from south-central Minas Gerais, Brazil: Red-and-white Crake Laterallus leucopyrrhus (closed/ovoid/base nest with shells of white eggs), White-throated Woodcreeper Xiphocolaptes albicollis (cavity/without-tunnel/simple/platform nest with two immaculate white eggs), Southern Bristle Tyrant Phylloscartes eximius (closed/globular/lateral nest), Sharp-tailed Tyrant Culicivora caudacuta (high cup/lateral nest with three cream-coloured eggs), White-rumped Monjita Xolmis velatus (low cup/base nest with two immaculate white eggs) and Hellmayr's Pipit Anthus hellmayri (low cup/base nest with three pale brown eggs spotted dark brown).

Primeiro relato de atividade patogênica de Hirsutella thompsonii (Fischer) sobre o ácaro-da-erinose-da-lichia Aceria litchii (Keifer)

The litchi erineum mite, Aceria litchii (Keifer) is found in all producing regions attacking leaves and flowers of litchi plants. The mite attack young leaves and causes the erinea on leaf surface, which later become brown galls with velvety appearance. Severe attacks can cause leaf drop and destruction of branches end directly production affecting. In 2009 year it was registered a heavy infestation of the pest on litchi plants (Litchi chinensis Sonn.) in the municipality of Casa Branca, São Paulo, Brazil (2127'O; 4702'S; 679 m altitude). In June, many galls caused by mite infestation showed a mycelium of white coloration and many eriophyid dead. The fungus was identified as Hirsutella thompsonii (Fischer). The results suggest that galls may facilitate the fungus development and its permanence on the plants. Thus, the possibility of mite biological control with H. thompsonii should be investigated.

Qualidade física de ovos armazenados em diferentes condições de embalagens sob temperatura ambiente

The objective was to evaluate the internal quality of white-shelled consume eggs, sanitized or not, stored under different packaging conditions at room temperature. It was used 300 eggs, distributed in a completely randomized experimental design in a 3×2×4+1 factorial arrangement, three packaging conditions (PVC film, partial vacuum, partial vacuum with oxygen gas absorber), storage period (7, 14, 21 and 28 days), sanitized or not, and control (fresh eggs), with four repetitions. At the end of each period the analysis were performed. Partial vacuum condition was able to maintained Haugh unit, and promoted the best results for yolk index. The weight maintenance was better when packaged under vacuum, with or without O2 sachets absorbers. Lower values of water activity were obtained in eggs packed in PVC film, and when the sanitation was performed. It can be concluded that the internal egg quality decreases with storage time sharper in the eggs packed in PVC film, because vacuum has preserved some features of them. With sanitation, the storage conditions of eggs in PVC film should be improved because its internal quality decrease was greatest.

Associação entre nível de atividade física e ocorrência de comorbidades de pacientes hipertensos em tratamento ambulatorial

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Fracionamento da proteína e estudo termoanalítico das leguminosas: grão de bico (Cicer arietinum), variedade Cíciero e tremoço branco (Lupinus albus L.)

Pós-graduação em Alimentos e Nutrição - FCFAR

Otimização para a obtençao de extrato aquoso de tremoço branco (Lupinus albus L.) adicionado de suco de pitanga

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Avaliação do fator de transformação do crescimento-beta 1, interleucina-10 e interferon-gama em cães machos, assintomáticos e sintomáticos, naturalmente infectados por Leishmania (Leishmania) chagasi

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Modelos para estimar as exigências de lisina digestível para poedeiras comerciais

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Reação de aveia branca, feijão, sorgo e trigo a Meloidogyne incognita, M. javanica e M. enterolobii

Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

Estudo da qualidade de vida de religiosas idosas

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

Aceria litchii (Keifer) em lichia: ocorrência sazonal, danos provocados e identificação de possíveis agentes de controle biológico

Pós-graduação em Agronomia - FEIS