109 resultados para 418


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O objetivo da autora aqui é discutir como se dá, no trabalho da romancista e contista escocesa Muriel Spark (1918-2006), a constituição das personagens femininas e a forma como estas veem a si mesmas e aos outros. A análise tem como base a coletânea composta de 41 contos publicada em 2001 sob o título de All the Stories of Muriel Spark (inédita no Brasil), cujas narrativas, em sua maioria, já haviam sido publicadas anteriormente em outras coletâneas ou em outros meios, como jornais e revistas. A autora também estuda nos contos o modo como os textos da escritora revelam sua visão peculiar do mundo e dos indivíduos, que foi se tornando mais amarga, embora mais compreensiva, com o passar do tempo. As narrativas curtas sparkianas se distinguem por refletir os diferentes contextos históricos vividos pela escritora: há contos que têm como ambiente a África, onde ela viveu nos anos 1930 e 1940, outros que se passam na Europa do pós-guerra e ainda os contos escritos mais recentemente. De passagem, a pesquisadora também analisa o engajamento político e ideológico de Muriel Spark, cuja vida conflituosa não a impediu de alcançar considerável sucesso de crítica e público nos países de língua inglesa. Sua obra-prima, o romance Primavera de Miss Jean Brodie (1961), foi adaptada para o cinema - o filme foi exibido no Brasil sob o título Primavera de uma Solteirona

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Objetivo : Descrever um novo sinal clínico associado à síndrome de negligência unilateral (SNU) em pacientes com acidente vascular cerebral isquêmico (AVCi). Método : Em 150 pacientes com acidente vascular cerebral isquêmico, foram realizadas tomografias de crânio e aplicada a National Institute of Health Stroke Scale. Aqueles pacientes com lesões vasculares à direita, hemiplegia esquerda e perna direita persistentemente cruzada sobre a esquerda, foram submetidos a testes específicos para SNU. Trinta pacientes também com lesões vasculares à direita, hemiplegia esquerda, porém sem evidências de permanecerem com as pernas cruzadas, foram submetidos aos mesmos testes clínicos. Resultados : Entre 150 pacientes com AVCi, 9 apresentaram lesão vascular cerebral à direita, hemiplegia esquerda e tendência em permanecer com a perna direita cruzada sobre a esquerda. Em 8 deles, testes específicos realizados nos primeiros dias de internação, confirmaram SNU à esquerda. Um paciente morreu antes que os testes pudessem ser aplicados. Dos 30 pacientes que não cruzaram as pernas, os testes foram normais em 20. Dez pacientes apresentaram alterações mínimas, insuficientes para o diagnóstico de SNU. Conclusão : A perna direita cruzada sobre a esquerda pode representar um novo sinal semiológico associado à hemiplegia esquerda e SNU à esquerda.

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Pós-graduação em Agronomia (Genética e Melhoramento de Plantas) - FCAV

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Teleost fish underwent whole-genome duplication around 450 Ma followed by diploidization and loss of 80-85% of the duplicated genes. To identify a deep signature of this teleost-specific whole-genome duplication (TSGD), we searched for duplicated genes that were systematically and uniquely retained in one or other of the superorders Ostariophysi and Acanthopterygii. TSGD paralogs comprised 17-21% of total gene content. Some 2.6% (510) of TSGD paralogs were present as pairs in the Ostariophysi genomes of Danio rerio (Cypriniformes) and Astyanax mexicanus (Characiformes) but not in species from four orders of Acanthopterygii (Gasterosteiformes, Gasterosteus aculeatus; Tetraodontiformes, Tetraodon nigroviridis; Perciformes, Oreochromis niloticus; and Beloniformes, Oryzias latipes) where a single copy was identified. Similarly, 1.3% (418) of total gene number represented cases where TSGD paralogs pairs were systematically retained in the Acanthopterygian but conserved as a single copy in Ostariophysi genomes. We confirmed the generality of these results by phylogenetic and synteny analysis of 40 randomly selected linage-specific paralogs (LSPs) from each superorder and completed with the transcriptomes of three additional Ostariophysi species (Ictalurus punctatus [Siluriformes], Sinocyclocheilus species [Cypriniformes], and Piaractus mesopotamicus [Characiformes]). No chromosome bias was detected in TSGD paralog retention. Gene ontology (GO) analysis revealed significant enrichment of GO terms relative to the human GO SLIM database for growth, Cell differentiation, and Embryo development in Ostariophysi and for Transport, Signal Transduction, and Vesicle mediated transport in Acanthopterygii. The observed patterns of paralog retention are consistent with different diploidization outcomes having contributed to the evolution/diversification of each superorder.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Considering that persistent organic pollutants (POPs) including synthetic substances belonging to differents organic functions, including organochlorine pesticides (OCPs), which are the most persistent and bioaccumulative, with high toxicity to humans and animals. Accordingly environmental and biological monitoring is necessary, in order to have greater control regarding the irresponsible use of these products. Though there are several analytical methodology reported in the literature to make determinations of this pesticide, they present some difficulties, requiring several steps to make the clean up of the sample. The proposed project aims to optimize a new analytical method that allows to perform the extraction of organochlorine pesticides in fish tissues, employing acetone as solvent assisted by ultrasound bath, making the method more quickly and not requiringfurther steps to purify the sample. Were analyzed the recoveries of pesticides in study in samples of tilapia average values: Heptachlor=84,7±9,8%; Aldrin=87,3±3,5%; Endosulfan=101,4±18,6%; DDE= 90,5± 3,3%, Endrin=102,2±13,8%., DDD=92,1±19,9%; DDT=90,8±6,8%. The real samples showed values granted for our legislation and low values of error

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Physics is in its development a major challenge to relate fields, this paper presents a proposal to relate classical fields of physics, ie the electric field, magnetic field and gravitational equations by time-dependent. The proposal begins with the work that determines the Cauchy-Riemann conditions for quaternions [1], and the determination of Laplace’s equation in four dimensions[3], it was possible to determine mathematical components important to make the couplings of classical fields discussed above.

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A shift of the photoluminescence (PL) emission was observed in ZnS prepared by microwave assisted solvothermal method with the increase of the time in microwave. In this work we reported a study of the optical behavior linking with the structural disorder according to XRD and FEG-TEM results. The reduction of intrinsic defects in the lattice is responsible for the decrease of electronic levels in the band gap changing the PL profile. This effect was confirmed by electronic structure calculations.

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The aim of this research is to analyze the extension of changes in technological strategies of a group of Brazilian pharmaceutical companies, which we believe were induced by transformations in the institutional environment during the 1990s. Major institutional changes, such as the enacting of laws that recognized drug patents rights and fostered generic drugs market, have strengthened the market insertion and competitive position of these companies, what would enable an increase in research and development efforts in Brazil. In addition to the literature on technology strategy and drug industry, this study was based on interviews with six Brazilian pharmaceutical companies, all of which were ranked among the top national companies in the industry and have been considered in previous studies particularly active in the process of changing technological strategies. This research confirmed a significant intensification of technology efforts carried out by Brazilian drug companies. Nevertheless, the R&D intensity is still far below the global pattern and innovative impacts are slight.

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The objective of this study was to assess if the positioning of the impression tray could cause plaster casts distortion during gypsum setting time. fifteen pairs of master models were cast with alginate impression material and immediately poured with gypsum. impressions were allowed to set with the tray in the not inverted position (group a) or in the inverted position (group b). the plaster models were digitized using a laser scanner (3shape r-700, 3shape a/s). tooth size measurements and distances were obtained using o3d software (widialabs, brasil) measurement tools. data were analyzed by paired t test and linear regression with 5% significance. most measurements of both groups were similar, except for the lower intermolar distance. it was not possible to corroborate the presence of distortions owing to the position of the impression tray during gypsum setting time.

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The orthodontic movement is a result of the system of forces application and it depends on the response of periodontal tissues to this system. The forces must have a magnitude considered ideal, to has maximum response of tissue without pain or root resorption, and keep the health of the periodontal ligament, during all the tooth movement. Therefore, it seems adequate by means of an available literature to estimate parameters of ideal force, for different types of movements; with intention of assisting the orthodontists in optimum control of the tooth movement and thus to diminish the possibility to generate deleterious effects.