Estudo da correlação linear entre a dimensão da largura maxilar e as dimensões das larguras de outras grandezas, lineares, transversas da face, em portadores de fissura transforame incisivo unilateral, através da cefalometria radiográfica, em norma frontal

This research presents the results of a cephalometric radiography study, in frontal norm, that was used to measure the possible linear correlations between several linear dimensions of the face, in a sample of a 140 caucasian brazilians, with an average age of 20 years, who were distributed in 2 groups as follows: Control group - formed of 35 males and 35 females, with no apparent facial deformities and with dental oclusion, not necessarily, in Angle's Class I; Unilateral cleft lip and palate group - formed of 35 males and 35 females with surgical correction of the up in the first year and of the palate until the third year of life, without orthodontic treatment. ln each teleradiography, the following parameters were measured using a computer: - Lateral orbit width or external orbit width (LOe) - Medial orbit width or internal orbit width (LOI) - Zygomatic width or facial width (LZI) - Mastold width (LMa) - Maxilar width (LMx) - Nasal width (LNa) - Condilar width (LCo) - Antigonial width (LGa) The values obtained were treated statistically using quantitative analysis (arithmetic mean, standard deviation, standard mean error, Person's variation factor and Pearson factor linear correlation). Theirs significance was established by Student's t test. The Pearson factor linear correlations determined between transverse linear cephalometric width dimensions of face in frontal norm for individuals of both groups and sex, with an average age of 20 years, were: ...

Anticorpos naturais e infecção: anticorpos naturais na doença de Chagas e na paracoccidioidomicose

Using ELISA technique, natural antibodies against self and non self antigens were determined in 80 patients chronically intected by T. cruzi and 40 individuals suffering from a deep mycosis frequentely found in Latin Amarica (Paracoccidioidomycosis - PCM). Two forms of PCM were investigated: adult forms and juvenil type of disease. Eighty percent (80%) of the former group had significantly elevated anti-laminin antibody levels (M=4.7,SD±1.8) compared with healthy controls and different specificities of antibody were associated with anti-laminin in pathological sera. A notable binding to cytoskeletal proteins was observed, specially with band 3 and their peptides derivates, such as 62 kDa peptide. By means of Protein A chromatography we were able to show that natural anti-Gal antibodies may be bound by their Fab region to other immunoglobulins and/or to Protein A by alternative sites of binding. The finding of lgG anti-Gal antibodies in circulating immune complexes isolated from chagasic sera supported the first alternative. However, it is possible that some of lgG anti-Gal antibodies, belong to VH111 subgroup of immunoglobulins, that bind directly to Protein A. Among the 40 sera from PCM examined, the majority was considered as not exhibiting a signilicantly higher binding than normal sera to antigens tested. However thirty percent (30%) of the chronic patients had an increased levels of natural antibodies at least for one specificity such as actyn, myosin and Gala1,3Gal epitopes. ln juvenil type of PCM the mean value found for actyn was also increased 2,42 (range 1,0 to 5,3). Utilizing the polyethylene glicol precipitation the presence of circulating immune complexes was investigated in PCM sera. Specific antibodies for soluble antigens from P. brasiliensis and natural antibodies against myoglobin, myosin and Gala1,3 Gal epitopes were characterized

Estudo anátomo antropológico do processo mastóideo e suas relações musculares

Os processos mastóideos de 305 crânios humanos identificados foram estudados com a finalidade de melhor compreender suas características morfológicas básicas, bem como suas relações com outras formações ósseas da área mastóidea. Foram mensuradas, além das várias medidas gerais do crânio, a altura e a largura dos processos mastôideos, a distância bimastóidea e bi-supramastóidea. Foram estudados: a incidência e a forma do processo paramastóideo, do sulco do processo mastóideo e da rugosidade da superfície lateral do processo mastóideo. Todos os resultados ósseos foram submetidos à análise estatística, relacionando-os ao sexo, grupo étnico e forma do crânio. Objetivando um melhor entendimento das formações anatómicas que se relacionam com os processos mastóideos, foram dissecados, em vinte cabeças humanas (quarenta lados), os músculos estemocleidomastóideo, esplênio da cabeça, longo da cabeça e ventre posterior do digástrico. As inserções destes músculos foram mensuradas, tendo-se como referência o plano aurículo-orbital. As áreas de fixação no osso foram medidas através de um analisador de imagens. De maneira geral as características ósseas estudadas mostraram que existem diferenças estatísticas significantes nos grupos formados por sexo e forma do crânio. Os caracteres estudados para a determinação do sexo dos crânios mostraram-se estatisticamente confiáveis, indicando a possibilidade da utilização do processo mastóideo para a determinação do sexo de crânios humanos. As dissecções realizadas mostraram que há relação funcional entre os músculos e as formações ósseas da área mastóidea, principalmente entre o ventre posterior do músculo digástrico e o processo paramastóideo

Concepção morfológica de fórceps, para intervenção no paciente em posição supina e o operador sentado

Ergonomics, the science of working rationalization, seeks the best relationship between man and his working tools. In Dentistry, ergonomics is present as for the professional working correctly seated, in functional comfort, intervening of supine position patient, by means of suitable equipment and instrument. Nowadays, dental equipment is justly rationalized; however, some instruments should take shape, in order to adapt those requirements. The hand tool design should permit a comfortable, non-slip and safe handling. Thus, anatomical details, the correct position of the operator for its use and specific characteristics of application should be taken into account. The instrument under analysis - forceps - was conceived according to these requirements along with a new alveolar tooth extraction technique, based on electromyographic and biomechanical studies. The morphology of the instrument, which makes possible a simple and natural kinetics of the operator, was obtained by changing the paradigm of the conventional cross-action instruments (whose grip is always on the arms of the tool), divesting the handle from the tool arm. This induced on anatomical conceiving of perpendicular handles to the extremity of the tool arm, resulting an efficient and effective instrument, according to indicated on its experimental phase

Avaliação dos ciclos de polimerização da resina acrílica para base de prótese total

In the present work it was studied the behavior of four water bath curing cycles of heat activated acrylic resin considered as long duration (I – 65ºC for 30 min;50ºC for 23h and 30min; and 100º C for 1h; II- 50ºC for 24h and the rapid cycle), compared to the known long time curing cycle (9 hours for 72ºC) and short curing cycle (1 h for 65ºC; 30 min to elevate at 100º C and 1:00 to 100º C). Analysis consisted of observations and verification of the residual monomer, weight alterations, dimensional, dimensional lineal, porosity and hardness to determine material performance. The results pointed out that residual monomer presented statistical significant differences in the factor storage and interaction among the factors cycle X storage for weight alteration; statistical significant differences for the factor storage for lineal dimensional alterations, without significant differences for hardness. Porosity was verified in minimum degree in the cycle III and in appreciable amount in the cycle IV

Estudo experimental do polietileno poroso de alta densidade (MEDPOR) fixado ao leito cirúrgico corticalizado e decorticalizado: análise histológica em cães

The aim of this study was to evaluate the influence of the bed in High Density Porous Polyethylene (Medpor) implants integration. Two different kind of beds -- corticalized and decorticalized -- were made in six dogs. The animals were killed thirty, sixty and ninety days after implantation. Blocks including implant and adjacent bone were harvested, submitted to histological procedures, stained in hematoxiline-eosine and analyzed in optic microscope. The results demonstrated an absence of infection and foreign body reaction associated with High Density Porous Polyethylene (Medpor) implants. Furthermore, bony and fibrovascular ingrowth could be observed into its pores. The best integration was noted in decorticalized group, in which occurred a greater bony and fibrovascular ingrowth in comparison to the corticalized group

Avaliação in vitro da resistência adesiva ao cisalhamento entre a dentina bovina, cimentos resinosos e materiais restauradores indiretos, tratados ou não com jato de óxido de alumínio, ácido fluorídrico e silano

The purpose of this study was to evaluate in vitro the shear bond strenght to bovine dentin, during 24h and 30 days with the following variables: resin cements Enforce and Panavia F; aesthetics restorative materials Art Glass, IPS Empress 2 and Targis, with surface treatment with microetching with aluminium oxide, fluoridric acid and silane. Two hundred eighty eight sound bovine teeth from 3 years old animals constituted the samples after inclusion on polyester resin box. lnstron model 430 Universal Testing Machine, a crosshead speed 0,5 mm/min and load cells of 500 Kg, was used for shear bond strenght testing (MPa). The results were statistically analysed by ANOVA The best result was obtained with /PS Empress 2, microetched with aluminium oxide, fluoridric acid and silane, cemented with Panavia F and stored in distilled water, 3f'C during 30 days

Influência ao consumo crônico de álcool no fêmur de ratos machos e fêmeas

Considering that alcohol has been identified, in the literature, as an evident risk factor for osteoporosis development, inducing loss of bone mass, the aim of this study was to evaluate the effect of the alcohol on the femur of male and female rats. For this purpose, 35 male and 35 female rats, divided into seven groups of five animals per genera were included. The groups were: control group that received food and water as much as they wished; alcohol group in the concentrations of 10, 20 and 30% and the isocalorie: groups corresponding to the concentration of alcohol. After 8 weeks, the animals were sacrificed and evaluated regarding to the body weight and nutritional conditions. Unilateral femurs were removed and analyzed in relation to the length, width, and thickness of the bone cortical, trabeculae percentage and optical density. Data obtained were analyzed by ANOVA (Tukey; p<0.05). Regarding to the weight, loss of weight was observed in the animals of the group alcohol 20% among females and 30% among the males. In relation to the nutritional conditions, the females with the dosages of 10, 20 and 30% of alcohol swallowed a mean of 25, 39 and 53% of Kcall and the males 22, 36 and 45 Kcal Jday coming from the alcohol. Alcohol reduced the length of the femur only in the group MG6. Mesio-distal width was higher in the group FG6 although the antero-posterior width was not modified. The cortical thickness among males and females was not altered however the percentage of trabeculae bone was reduced among females alcohol 30% and among males with the three alcoholic concentrations. Optical density was reduced in the concentration of 30% among the males and females. Under the experimental conditions, it could be concluded that the effect of alcohol was more evident among the males and in the trabeculae bone, and that the alcoholic concentration of 30% was the most harmful for the bone tissue, ....

Efeitos dentoesqueléticos do tratamento da classe II utilizando o aparelho de Herbst associados à mecânica Straight-wire

This study compared the effect of the treatment protocol for correcting Class Il malocclusion using the Herbst appliance followed by full fixed Straigh-wire mechanics, in two populations, one Brazilian and one of North American origin As a untreated control sample the data from the University of Michigan Elementary and Secondary School Growth Study (UMGS) was used. Our sample was composed of 12 males and 12 females, with initial mean age of 12 years 7 months and final mean ages of 15 years and 3 months. The Michigan patients comprised 21 females and 7 males, with an initial mean age of 11 years and 9 months and final mean age of 14 years and 4 months. The control sample was paired in number, sex and age to the treated Michigan sample. ln both treated groups, lateral cephalometric radiographs were obtained before the Herbst appliance was cemented and at the end of the fixed appliance phase, The first comparison involved the Brazil group and the untreated controls, which demonstrated that the association of the Herbst appliance followed by fixed Straight-wire appliances provoked positive effects on the dentofacial complex, improving pre-existing maxillo-mandibular relationships, besides increasing dentoalveolar compensations which contributed to correct the malocclusion. The second comparison, involved the Brazl1ian and North-American patients treated with the same protocol. Although the pre-treatment comparison showed that the two groups were not similar in all aspects, they presented almost identical therapeutic modifications, which indicate that the effect of' treatment was very similar. These results point out that, in Class ll treatment, the combination of Herbst/Straight-wire mechanics produce consistent and systematic effects, correcting or minimizing possible skeletal imbalances

Avaliação da expressão de citoqueratinas na citologia esfoliativa da mucosa bucal de pacientes fumantes

The present study compared the expression of cytokeratins CK6, CK16 and CK19 and pan-cytokeratin (PAN) in oral mucosa cells between smokers and nonsmokers in order to determine the stage of cell differentiation and to consequently infer proliferative activity and expressions indicative of a potential for malignant differentiation. Thirty smokers and 30 non-smokers seen at the clinics of FOSJC-UNESP were screened. Smears were obtained from the left lateral border of the tongue with a cytobrush and slides were processed for immunohistochemistry using the antibodies reported Conventional microscopy was used for qualitative analysis. The results were analyzed statistically by the Z test, Fisher's exact test and comparison of two proportions (plus-4 confidence interval method). The expression of CK6 (p=0.002), CK16 (p=0.003), CK19 (p=0.0001) and PAN (p=0.008) was higher in oral mucosa smears from smokers compared to non- smokers. ln conclusion, increased epithelial proliferation is observed in the oral mucosa of smokers as demonstrated by the increased expression of CK6 and CKJ6, and these cells present alterations in epithelial maturation

Uso de extratos vegetais no controle in vitro do Colletotrichum gloeosporioides penz. Coletado em frutos de mamoeiro (Carica papaya L.)

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Estimating the average length of hospitalization due to pneumonia: a fuzzy approach

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Ecophysiology of seed germination in Digitaria insularis ((L.) Fedde)

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

Identificação de padrões da dengue em municípios paulistas entre os anos de 2003 a 2011

Pós-graduação em Biociências - FCLAS