334 resultados para vitamina A


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Pós-graduação em Zootecnia - FCAV

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Pós-graduação em Fisiopatologia em Clínica Médica - FMB

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Pós-graduação em Ciências Biológicas (Biologia Celular e Molecular) - IBRC

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Pós-graduação em Biologia Geral e Aplicada - IBB

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Pós-graduação em Fisiopatologia em Clínica Médica - FMB

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Pós-graduação em Zootecnia - FCAV

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)

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Pós-graduação em Ciência e Tecnologia Animal - FEIS

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Vitamin A is important to the proper development and functioning of the body, appearing in several metabolic functions. This experiment was conducted with aim evaluate to the vitamin A supplementation in diets for Goldfish Carassius auratus. The experimental was completely randomized with six treatments (0, 2.000, 4.000, 8.000, 16.000 and 32.000 IU of vitamin A kg(-1) diet) with four repetitions into 24 experimental cages, with capacity for 150 liters useful volume, made of mesh shading, installed inside a masonry circular tank with a capacity of 25 m(3) of water. 192 fish with an average initial weight of 6.66 +/- 0.57 g and initial length of 7.30 +/- 0.33 cm, feed at 8h, 11h, 14h and 17h at satiety were used. Evaluated the effects on productive performance and intensity of yellow-red coloring of the skin of the fish were. The Linear Response Plateau analysis of weight gain and length total, feed conversion and daily growth rate versus vitamin A requirement estimate showed 2,624, 2,385 and 2,358, 4,381 and 2,866 IU of vitamin A per kg diet, respectively. The data indicated that this vitamin has little or no influence on the intensity of the skin color of the Goldfish.

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The aim of this study was to verify if α-tocopherol, the main substance of Vitamin E and also the one with the major antioxidant propriety, could offer citoprotection to a stomach damaged by alcohol. There are many forms of α-tocopherol, two forms of them were evaluated; d-l-α-tocopherol, the synthetic form and d-α-tocopherol, the natural form of α-tocopherol. Three experiments were made, all of them having absolute ethanol as the lesion agent, but the period and the doses changed in each of them. In the first two experiments, each group of animals received a different form of α-tocopherol and in the third experiment, they’ve received α-tocopherol p.o. for the period of seven days before the lesion agent was administrated. Moreover, immunohistochemistry assays were made from the stomachs samples of the third experiment to verify possible mechanisms involving nitric oxide and 2-cyclooxygenase. Satisfactory results of citoprotection have been obtained when the two forms were administered in the period of one week at doses of 100 mg/kg for synthetic form and 150 mg/kg for natural type. Nevertheless, the two forms didn’t differ statistically in their effectiveness against ethanol. The immunohistochemistry assays showed an increase of the levels of NO and COX2 in relation with the negative control, although there was no correlation between this increase and the gastroprotective effect. In conclusion, α-tocopherol has gastroprotection effect in some doses, but apparently there is no such a thing like the better the dose, the better the effect; that citoprotection don’t have a relationship with NO neither with COX2; the natural and the synthetic form don’t differ in their gastroprotection effect. More studies must be done looking forward an effective dose and also to understand the mechanisms underlay the citoprotection of α-tocopherol in the stomach