115 resultados para Uso racional de antimicrobianos


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The use of electricity for obtaining light has been quite an issue currently discussed, either through new technologies that are emerging, the quest for greater efficiency, reduced waste and rational use. This work comprises a lighting design applied to a metallurgical based Brazilian Standard 5413 which mentions levels of luminance for interior and, in the case of this work, for a sandblasting booth. Ways to improve the workplace and luminosity presented before the project and also after its implementation are discussed. Technologies are chosen guided by technical calculations according to the illuminance values they want to reach for the environment studied. All pertinent design features are critically analyzed and discussed, and at the end proposals are presented, relating to each other in a comparative framework, so the best solution is applied in a practical way in the enclosure. Results are also presented concerning the maintenance of a bank of capacitors to correct the power factor for the metals studied company

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Pós-graduação em Microbiologia Agropecuária - FCAV

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Due to concerns about rational use of energy, several alternative technologies of power generation appeared, including the conversion of solar energy into electrical energy by photovoltaic panels. In low-income households, the refrigerator represents considerable impact on the electric bill, since it requires constant power given its use in food preservation. It is possible to reduce this share, with the use of an alternative energy source. This work presents a timed switching electronic system, which allows commercial equipment that is not affected by short interruptions in the power supply to use a photovoltaic panel as a source of alternative energy, which usually do not provide energy continuously. Switching is made automatically in case of low incidence of sunlight, and without any form of energy storage. Between each switching, there is a dead time without power supply, therefore preventing the use of synchronizers circuits between the photovoltaic panel and the public power grid. A circuit containing a 80C31 microcontroller is used to control the system’s switching. The photovoltaic panel’s voltage inverter is in H bridge configuration, and is also controlled by the microcontroller through Pulse Width Modulation, which makes use of preprogrammed tables to generate the control signals of the power transistors. Through the use of software simulations, the proposed system was tested, which is capable of supplying intermittent single-phase loads. The simulations indicates that the project developed in this paper can be assembled into a prototype and be tested under real operating conditions, as long as the scaling of components, the characteristics of the photovoltaic panel to be used, and the project involved load are taken into account

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Os Medicamentos Isentos de Prescrição (MIPs) são de venda livre que têm como propósito tratar sintomas e distúrbios menores, sendo responsáveis pela movimentação de bilhões de dólares a cada ano mundialmente. É permitida a veiculação de propagandas direta ao consumidor, não sendo obrigatória a apresentação da prescrição. A disponibilidade e o consumo de MIPs podem impactar a saúde, economia e a promoção do uso racional de medicamentos, portanto se faz necessário compreender o comportamento e as motivações dos consumidores pelos MIPs e a prática da automedicação. Para tanto, conduziu-se um estudo entre março e junho de 2014 por meio de entrevistas com perguntas abertas referentes a classes terapêuticas adquiridas para automedicação, frequência com que os consumidores compraram MIPs e se automedicaram, os problemas de saúde que os motivaram a se automedicarem e a comprarem MIPs e à prática da automedicação. Foram entrevistados 47 consumidores entre 18 e 70 anos residentes em Araraquara/SP. A indicação familiar é o fator de influência mais recorrente (14), seguida pela indicação do balconista da drogaria (11) e amigos (6). A classe de MIPs mais consumida pelos entrevistados é a de analgésicos, que está relacionada com a ocorrência de dores de cabeça e musculares, sendo que a compra de MIPs ocorre, no mínimo, uma vez por mês. As motivações para a compra são principalmente o preço (33) seguido da marca (30). A automedicação ocorre também para o alívio de dores e a maioria alegou saber o conceito da automedicação porém, ainda assim, afirmou administrar por conta própria medicamentos MIPs e/ou sujeitos a prescrições, sem orientação de um profissional de saúde.

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Over the years, water has become an increasingly valuable resource and scarce, this situation is attributed to factors such as population growth, poor distribution and increasing degradation of water resources as a result of indiscriminate human activities in the middle environment, making their dwindling availability and increasing its cost. I n this context , the use of rainwater for non-potable purposes begins to be stimulated in Brazil , as a measure to preserve this resource , while in countries such as Japan and Germany , this technique has already been used for a long time. The ability to capture rainwater reduces the demand for sanitation companies, also resulting in cost reduction with the water bill and the risk of flooding in the event of heavy rains. The stored water is used only for non-potable purposes, such as toilets, taps into the garden, for washing vehicles and clothing. This work was developed with the aim of presenting the importance of rational use of water, associated with viability constructive economic and consumption of the installation of rain water harvesting, and for that, considered four case studies. From this study, it was found that the implementation of this system has led to a reduction in costs of water and sewer consumption poses no hazard to the user and its installation does not require significant changes in building construction, however, in relation to the economy, should be made a detailed analysis in each case for investment to bring a suitable financial return within the lifetime of the system

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Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)

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Pós-graduação em Agronomia (Energia na Agricultura) - FCA

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As atividades dos estabelecimentos de abate de frangos são conhecidas por utilizarem grandes volumes de água durante seus processos, principalmente no processo de resfriamento das carcaças de frangos. Parte desse volume utilizado se faz necessário, em cumprimento à legislação que determina que cada tanque do sistema de pré-resfriadores contínuos por imersão deve ser completamente esvaziado, limpo e desinfetado no final de cada período de trabalho (oito horas). O objetivo deste estudo foi comparar a carga microbiana das águas do sistema de resfriamento e das carcaças de frango ao final de oito, dezesseis e vinte e quatro horas de trabalho do abatedouro, para possível redução do número de vezes do completo esvaziamento dos tanques do sistema de resfriamento. Foram avaliadas, por meio de métodos convencionais microbiológicos e físico-químicos, amostras da água de abastecimento (n=69), visando a evitar possível interferência nas contagens das águas do sistema de resfriamento, amostras de carcaças de frango antes (n=345) e após (n=345) sua passagem pelo sistema de resfriamento e amostras de águas do último estágio do sistema de resfriamento de carcaças (n=69). Os resultados obtidos demonstraram que não houve diferença significativa na carga microbiana das amostras entre as três jornadas de trabalho do estabelecimento, sugerindo que a redução é segura, diminuindo assim o volume de águas residuais e seu impacto no meio ambiente, bem como melhorando o uso racional do tempo de processamento.

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Pós-graduação em Ciência Florestal - FCA

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)

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The use of antimicrobial agents has facilitated the dissemination of multi-resistant microorganisms, compromising dental and medical treatment. The aim of this study was to evaluate the distribution of different opportunistic microbial species in patients who suffered head and neck trauma, under temporary maintenance in nosocomial environment, particularly intensive care units, on the occurrence of such microorganisms in the oral cavity of the patients. It was selected 38 patients subjected to head and neck traumas. After emergency surgical procedures, clinical samples of saliva, sub and supragingival biofilms and mucosal surfaces were collected at two different moments: just after stabilization of the patient and soon after patients’ release from medical units. The presence of opportunistic and superinfecting microorganisms was evaluated by culture on selective and non-selective media, and the presence of the family Enterobacteriaceae, as well as genera Enterococcus, Pseudomonas, and Staphylococcus was assessed by PCR. It was found that the use of antimicrobials, even for short periods of time was sufficient to facilitate colonization by microorganisms of the families Enterobacteriaceae and Pseudomonadaceae, as well as yeasts and enterococci. These results support the concept that medical and dental teams should make a periodically change of antimicrobials used in treatment protocols in hospital for head and neck trauma patients, in order to minimize dissemination of opportunistic or superinfecting microorganisms.

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The ageing process can change the pharmacodynamics and pharmacokinetics parameters. Therefore, some medications are considered potentially inappropriate (PIM) for the elderly people, since they can increase the likelihood of occurrence of adverse drug events. The objectives are to estimate the frequency of use of PIM in the elderly people, with potentially hazardous drug interactions (PHDI) and to evaluate the impact of pharmaceutical intervention (PI) for the prescription of safer therapeutic alternatives. A cross-sectional study was performed in a Health Family Strategy (region of Araraquara, SP), between January and February/2012. The medical records of patients aged ≥60 years, that use at least one drug, were consulted for identification of PIM, according to the Beers criteria. The MPI identified were classified considering the Anatomical Therapeutic Chemical Classification System (ATC) and the essentiality of the drug (safety, effectiveness, quality and cost parameters) The inclusion criteria were met by 358 elderly, being that 93 of them (26%) had taken at least one PIM. Of the 114 different drugs prescribed for elderly, ten were classified as PIM, of which four of them act on the central nervous system, four on cardiovascular system and two on the digestive tract. Seven MPI are essential medicines, belonging to national list of essential drugs (RENAME-2010). Fourteen drug interactions were identified, of which two are PHDI (fluoxetine/amitriptyline and digoxin/hydrochlorothiazide).After the PI, there was no change in medical prescriptions of patients with PIM use or with DI. Medical prescriptions of elderly attended in the Health Family Strategy show pharmacotherapeutic safety problems, of which may be responsible for health hazardous for this age group. Although the intervention carried out by letter had been ineffective for the adherence of doctors in prescribing safe alternatives, wide dissemination of the lists that contain PIM and PHDI is need, as well as the inclusion of safer equivalents in RENAME, in order to contribute for rational use of drugs.

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)